🚨 𝐀𝐈 𝐦𝐞𝐞𝐭𝐬 𝐓𝐁 𝐝𝐫𝐮𝐠 𝐝𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐲!

Imaging 𝐶. 𝑔𝑙𝑢𝑡𝑎𝑚𝑖𝑐𝑢𝑚 (a model for 𝑀. 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠) + deep learning reveals known, unseen, and novel antibiotic modes of action from images alone, a leap for TB drug discovery.

✍️ @awehenkel.bsky.social & coll.
📖 shorturl.at/9QPDy

#Tuberculosis #MicroSky

New toy in the lab ! a ‘Grid’ moment ☺️❄️🔬

Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO Journal Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev...

🎉 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐓𝐡𝐞 𝐄𝐌𝐁𝐎 𝐉𝐨𝐮𝐫𝐧𝐚𝐥!

After 8 months of revision, our work is now online: shorturl.at/WHmFq

We uncover a previously unrecognized way that 𝑀𝑦𝑐𝑜𝑏𝑎𝑐𝑡𝑒𝑟𝑖𝑢𝑚 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠 survives toxic metal stress during infection.
...

Exciting #postdoc opportunity in KL Ung's group!
Understanding the molecular mechanisms of cell wall remodeling in pathogens

Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM

Best thing is to come back from ⛰️vacation☀️ to find a manuscript has metamorphosed into a published paper, so..

🚀 Check out our paper on hormone import⏬ into plant cells in @natplants.nature.com 🌱👇

www.nature.com/articles/s41...

I'm thrilled to share that I’ve been selected for the #ATIP-Avenir 2025 Young Investigator Programme to support my new research group at @ipbstoulouse.bsky.social for the next 5 years! 🧑‍🔬🔬🦠🤩

FEBS Press Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate prec...

Glad to share J.Couston's @juliecouston.bsky.social
work published at The FEBS Letters @febsletters.bsky.social and done at @irim-life.bsky.social
.
doi.org/10.1002/1873...

🚨My new team at @ipbstoulouse.bsky.social in France currently have an open, fully-funded PhD position 🧑‍🔬👩‍🔬to study membrane proteins & transporters of therapeutic interest using cryo-EM & biophysics.🧊🔬🦠

#StructuralBiology #MicroSky

Please share 🤝
For more details 👇

Happy to share our latest work on the fascinating PIN-FORMED herbicide transporter 🌿🌻
We hope this research will provide a foundation for the rational design of next-generation, eco-friendly herbicides and the precision breeding of herbicide-resistant crops.
#MakeOurPlanetGreatAgain🌍

Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters - Nature Plants PIN transporters are key players in distributing phenoxyacetic acid herbicides. Mutagenesis and cryo-EM structures elucidate substrate specificity and transport mechanisms, paving the way for improved...

Finally out…
„Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters“ www.nature.com/articles/s41.... A collaboration between my group and @bjornppedersen.bsky.social led by the magic duo @lukas-schulz.bsky.social and @unglam.bsky.social

#CryoSPARC v4.7 is out! 🚀 
Featuring a new automatic Micrograph Junk Detector that labels and rejects contaminants, new tools for curating subsets of particles, performance and stability fixes, and more!
Full changelog: cryosparc.com/updates

#cryoEM

Shout-out to @pierredupuy.bsky.social and colleagues!
Excited to share our latest study, where we uncovered a previously unknown bacterial defense system in M. #tuberculosis: effluxosomes — dynamic membrane clusters that coordinate resistance to multiple toxic metals.
shorturl.at/Ek0HD
#MicroSky

I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of @neytsjohan.bsky.social 💊

"A coronavirus assembly inhibitor that targets the viral membrane protein"

www.nature.com/articles/s41...

A huge congrats to everyone involved! 🎉

After four years of postdoc, it was with mixed feelings that I said goodbye to Denmark. A sincere thank you to everyone @bjornppedersen.bsky.social lab, to friends and colleagues @molbiolau.bsky.social I was fortunate to meet during these years. 🥂☘️

Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️

Postdoctoral position in biophysical and structural characterization of auxin transport, Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University

Interested in structural biology, membrane proteins, biophysics and working onto understand hormone transport in plants?☘️🔬👩‍🔬🧪
We are recruiting a postdoc:
- Deadline 20. Dec 2024.
- 2(+2) year position.
- Details and application link: tinyurl.com/y7vnewen
- PM for questions
Please repost 💚

A postdoctoral position is available in our team to study the type VI secretion system.
Biochemistry, X-ray cryst and some cryoEM with @fronzeslab.bsky.social team
Reposts appreciated 😊

We made the cover of TiBS😁.👇

All thanks to Rune Kidmose and his amazing artwork.💚

In it, our review on PIN structures (also great illustrations there by Kien Lam Ung btw🤩)

www.cell.com/trends/bioch...