Posts by Lars-Anders Carlson
Our paper featured on TWIV with a nice analysis. @51min10secs
What will you do after that? I will probably join UPSC and study molecular mechanisms of flower development. If they take me.
So, OpenAI, whose entire business model relies on some overhyped dudebros using vast amounts of stolen data and stolen labour, is releasing a specialised GPT for the life sciences. And naming it, apparently without any sense of irony or self-awareness. Rosalind.
Happy Golgi Day
Thoughts?
#philosophy
I don’t know if you saw the MASSIVE news announced by @erc.europa.eu today: from now on, if you get a B at step 1 you are eligible to apply at N+3(!!!) years. Say you got a B in STG2026 step 1, you thought you could apply in STG2028, but no: only in STG2029! erc.europa.eu/news-events/...
I am so excited to share our new findings with you! We provide the structural evidence for a direct protein-to-DNA information pathway, showing how a bacterial enzyme 'reads' its own structure to 'write' DNA. www.science.org/doi/10.1126/...
Vaccine invented. Disease plummets. (Repeat)
Over the seven decades since the polio vaccine, we have seen this pattern again and again.
Vaccines have a great track record.
Note to self: do not get infected with VEEV.
A square graphic on a white background. At the top, there are two distinct, rough, painted-style brushstroke patches side-by-side: one in the blue and yellow of the European Union flag and one in the red, white, and blue of the United Kingdom's Union Jack. Below the flags, bold, dark blue text reads: "THE UK IS COMING BACK TO ERASMUS+." In the bottom right corner, there is a small, rectangular official European Union flag.
The United Kingdom is coming back to Erasmus+.
The European Union and the United Kingdom have enabled the UK's association to Erasmus+ in 2027.
More ↓
link.europa.eu/MHc9JP
Column chart of monthly reported human cases of H5N1 by world region from 1997 to 2026 where most cases cluster in Asia in the early 2000s, there is a very large spike in Africa around mid-2014, and a smaller spike in North America in early 2026. Data source: WHO, Global Influenza Programme (2026). License: CC BY.
📊 Track confirmed human cases of H5N1 “bird flu” since 1997—
Avian influenza A (H5N1), often referred to as “bird flu”, is a subtype of influenza virus that infects birds and mammals. In rare cases, humans can also be infected.
Now available - The Nanosoft 8-Pocket Autogrid Box - A #cryoem grid box with 8 pockets designed, shaped & sized for autogrids - Pockets are offset to make autogrid removal easier - Available in 6 colors & with a random, unique 5-digit serial number -> zurl.co/89dEH
Mother Nature is still the undisputed Queen of organic chemistry!
#Tick borne #encephalitis (TBE) is one of the most dangerous viral diseases spread in Europe. Researchers led by @lacarlson.bsky.social from 🇸🇪 @umeauniversitet.bsky.social have now discovered how the #virus replicates inside infected human cells, paving the way for future treatments. #TBE
1/ Excited to share our preprint! 🥳
Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine
www.biorxiv.org/content/10.6...
Blender Rendering of vitrified HA trimer with DM at the air-water interface
We identified the maltoside detergent DM as an effective and easy solution to address preferred orientation in cryo-EM. Helped me switch from graphene grids. Special congrats to Maria Rafiq! @landerlab.bsky.social @nanigrotjahn.bsky.social @wisemanlab.bsky.social #cryoEM doi.org/10.64898/202...
Hepatitis E virus replication is maintained in proliferative cells within the intestinal crypt www.science.org/doi/10.1126/...
Our colleague needs your help keeping a 1,200-year dataset alive!
If you have botanical expertise or are based near Arashiyama, Kyoto — DM her or email tuna@ourworldindata.org.
Y’all know I’ve been a serious skeptic regarding large language model technology in general and of its applications to education in particular.
I’m willing to admit where I’ve been mistaken though, and clearly I’ve been mistaken here. I pride myself as an instructor, but I can’t compete with this.
Wildlife trade drives animal-to-human pathogen transmission over 40 years
New in @science.org ‼️ In the most comprehensive study to date, we show that wildlife trade is driving animal-to-human zoonotic spillover at a planetary scale, with +1 spillover per host every 10 years. Live animal markets and illegal trade pose even greater risks. 🔓 www.science.org/doi/10.1126/...
Out now at PLoS Pathogens @plos.org. Nice collaboration with @danielhurdiss.bsky.social @utrechtvirology.bsky.social. Some beautiful glycoproteomics work by @tshamorkina.bsky.social mapping N- and O-glycan shield of coronaviruses infecting whales and dolphins 🐋🐬🐳.
journals.plos.org/plospathogen...
Earthset, courtesy of Artemis. Story by @katrinamillerphd.bsky.social Gift link: nyti.ms/4bVvp1R
Memory cells in the nose slow the #influenza #virus as soon as it enters the body. A study from the University of Gothenburg may help guide the development of better influenza #vaccines #research supported by Knut and Alice Wallenberg Foundation @angelettilab.bsky.social tinyurl.com/38cr3etp
Beautiful new review on how autophagy is hijacked by pathogens by Enoch & @tolgaboz.bsky.social
"𝘈𝘳𝘦 𝘵𝘩𝘦𝘳𝘦 𝘤𝘦𝘭𝘭 𝘵𝘺𝘱𝘦-𝘴𝘱𝘦𝘤𝘪𝘧𝘪𝘤 𝘰𝘳 𝘪𝘯𝘵𝘦𝘳𝘤𝘦𝘭𝘭𝘶𝘭𝘢𝘳 𝘤𝘰𝘮𝘮𝘶𝘯𝘪𝘤𝘢𝘵𝘪𝘰𝘯 𝘱𝘳𝘰𝘤𝘦𝘴𝘴𝘦𝘴 𝘮𝘦𝘥𝘪𝘢𝘵𝘦𝘥 𝘣𝘺 𝘢𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘥𝘶𝘳𝘪𝘯𝘨 𝘪𝘮𝘮𝘶𝘯𝘦 𝘳𝘦𝘴𝘱𝘰𝘯𝘴𝘦𝘴?"
Yes, there are - watch this space :-)
royalsocietypublishing.org/rsob/article...
Preprints thrive when embedded in an active scientific ecosystem 🎉
That's why we're excited to announce updated article-level commenting on @biorxiv-medrxiv.bsky.social, now powered by Hypothesis.
openrxiv.org/hypothesis-c...
#OpenScience #Preprints #bioRxiv #medRxiv
65 years after Peter Mitchell’s chemiosmotic theory, we report an association between ATP synthase and the electron transport chain. In the preprint led by @longzhou88.bsky.social, we describe a large supercomplex and show how the supramolecular organization contribute to oxidative phosphorylation 🧵
We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!
Ihre Forschung bildet die Grundlage für das nächste Jahrzehnt zellbiologischer Forschung und biomedizinischer Anwendungen. Herzlichen Glückwunsch zum #LeibnizPreis 2026, Julia Mahamid! 👏 (@embl.org)
Ihre Arbeit im Video: youtu.be/mtmAQxZ33y0?...
Misha, welcome to the virology club. :) Cool paper, I think we may need to JC it.