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Posts by The Banfield Lab

Congratulations @wshuai.bsky.social and co-authors!

We’re excited to introduce MODIFI, our new scalable method for detecting DNA modifications in PacBio metagenomic data and estimating ECE-host linkage.
Check out the preprint: www.biorxiv.org/content/10.6...

3 weeks ago 30 14 1 0

🌀 We solved the structure for T. denticola periplasmic flagella!

I'm very happy to finally showcase this work. A huge collaborative effort between myself, @bindusmitapaul.bsky.social, @debnathghosal.bsky.social, Jack Kim, @banfieldlab.bsky.social, Eric Reynolds and the Chris Fenno lab.

🦠 Enjoy!

2 months ago 19 9 1 1
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Today in Nature Communications, a team of IGI researchers from The Banfield Lab and Pam Ronald's labs uncover a new way to reduce methane emissions from rice by influencing the activity of rice paddy soil #microbes. Read more: https://ow.ly/45j150Y3WsI

2 months ago 15 7 1 0

🚨 New pre-print alert!
Jumbo circular extrachromosomal elements of methane-oxidizing archaea with variably extensive metabolic and defense gene repertoires

www.biorxiv.org/content/10.6...

2 months ago 14 7 0 0

Excited to share our discovery of archaeal circular, jumbo extrachromosomal elements (up to ~535 kb genomes). One related, 409-kb genome is integrated in CH4-eating Methanoperedens, representing the largest integrative element in Archaea so far! Curious about what they are doing? See the paper

2 months ago 18 12 1 1
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A new preprint from The Banfield Lab looks at mobile genetic elements with single-cell precision. Read here: https://ow.ly/hFBX50Y0nQA

#microbiology

3 months ago 10 3 1 0
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A new preprint on expanding the genetic code, from IGI's Jill Banfield, Peter Penev, and collaborators across the country: https://ow.ly/HiYO50XVNXR

3 months ago 14 4 0 0
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Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics Mobile genetic elements (MGEs), including plasmids and viruses, drive microbial evolution and ecosystem dynamics, yet their distribution, host range, and functions remain poorly understood, especially...

New preprint out: Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics
www.biorxiv.org/content/10.6...

@mingyan-igi.bsky.social

3 months ago 33 11 0 0
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Postdoc - Microbiome - Innovative Genomics Institute University of California, Berkeley is hiring. Apply now!

🚨 Our Lab is HIRING! If you are interested in characterizing model microbiomes using genome-resolved methods, statistical/metabolic modeling, and/or machine learning please submit an application here: aprecruit.berkeley.edu/JPF05234

#postdoc #sciencejobs #biology #microbiome

3 months ago 12 9 1 0
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Troubleshooting common errors in assemblies of long-read metagenomes - Nature Biotechnology Long-read sequence assemblies from metagenomes contain frequent errors.

Troubleshooting common errors in assemblies of long-read metagenomes - @merenbey.bsky.social @banfieldlab.bsky.social go.nature.com/44P7nSm

3 months ago 43 20 0 2
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✨New preprint!

🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al!
Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬

🔗👇

4 months ago 98 47 1 8
illustration of petri dishes growing microbes

illustration of petri dishes growing microbes

Out today in Science Magazine — First author Veronika Kivenson and PIs Jill Banfield (The Banfield Lab) and Alanna Schepartz team up to reveal a new genetic code in #archaea, with implications for #methane and #climate, and #bioengineering! Learn more: https://ow.ly/Kuem50Xurh0

4 months ago 15 6 0 0
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Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses - Nature Communications Borgs are large extrachromosomal elements of anaerobic methane-oxidizing archaea. Here, via in silico protein structure prediction of ~10,000 Borg proteins, the authors reveal that Borgs share numerou...

Out now in Nature Communications: Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses

www.nature.com/articles/s41...

@luisvalentin.bsky.social @lingdong-shi.bsky.social @martianmicrobe.bsky.social @mschoelmerich.bsky.social

4 months ago 70 28 0 3
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An archaeal genetic code with all TAG codons as pyrrolysine Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...

New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...

4 months ago 59 33 1 3

Incredible science coming out from our lab. Congrats @kivenson.bsky.social 🎉

5 months ago 13 5 0 0

Fresh from the press! Congrats @diamondlab.bsky.social

5 months ago 4 0 0 0

We tried to contact researchers at Sichuan Agricultural University who may have deposited this data (PRJNA601687) with no reply. Please let us know if you have any information.

6 months ago 1 0 0 0

Newest preprint from the group on megaplasmids in E. coli led by @assemblerag.bsky.social. In addition to our findings in metagenomic datasets, we identified an RNA-seq project from a giant panda gut sample with evidence of megaplasmids. We would like to include the data creators in our study.

6 months ago 9 3 1 0
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The 2025 Banfield Retreat was fantastic 🦠 so many talented scientists in one place is a sure way to come up with some great ideas!
@banfieldlab.bsky.social

11 months ago 4 2 0 0
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🚨 Fresh from the press! We created and analyzed over 100 in vitro cyanobacterial consortia using well-characterized model cyanobacterial hosts to better understand how cyanobacteria recruit and interact with their microbiomes.

Check it out: doi.org/10.1093/isme...

9 months ago 45 24 3 4
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Overturning circulation structures the microbial functional seascape of the South Pacific Global overturning circulation partitions the deep ocean into regions, each with different physicochemical characteristics, but the extent to which these water masses represent distinct ecosystems rem...

manuscript here! www.science.org/doi/10.1126/...

9 months ago 3 2 0 0
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Many of you gave me so much encouragement when I posted here earlier about my 10 year long passion project to make a microbial map of the ocean. Pinch me because I can't believe I get to update you that today that research was published in the journal SCIENCE! @science.org

9 months ago 18 10 4 1
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Structure of an archaeal ribosome reveals a divergent active site and hibernation factor - Nature Microbiology Sequence and structural analyses reveal a divergent peptidyl transferase centre and a hibernation factor in archaea.

Out now:

Structure of an archaeal ribosome reveals a divergent active site and hibernation factor

@jhdcate.bsky.social @banfieldlab.bsky.social @diptinayak.bsky.social & co

#microsky

www.nature.com/articles/s41...

9 months ago 49 18 1 0
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Tiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome Editing Tiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome Editing - Innovative Genomics Institute (IGI)

In a recent paper, IGI's @jenniferdoudna.bsky.social @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more in this Q&A with Steve: ow.ly/6Szs50VGElf

8 months ago 9 4 0 0

Most plasmids described in E. coli are small compared to the megaplasmids we identified here! Check out the preprint if you want to learn about these mysterious large elements and their potential functions 🧬. I’m very grateful to have had the opportunity to work on this in @banfieldlab.bsky.social

6 months ago 34 19 2 1

Excited to share new research led by our very own @lingdong-shi.bsky.social showing that many archaeal 23S rRNAs are circularized in active ribosomes. Check out the preprint below.

11 months ago 31 14 0 0

Genomes from long-read metagenomic assemblies contain rampant errors, highlighting the pressing need for stricter evaluation methods in long-read assembly algorithms. Read more in our paper with the Eren group. @floriantrigodet.bsky.social @merenbey.bsky.social

11 months ago 42 16 0 2