A very nice study showing that there is no obvious relationship between tubulin compaction/expansion state and its nucleotide state.
Indeed, there is no experimental data demonstrating that GTP-tubulin is expanded in the GTP-cap at microtubule growing ends.
1/3 Lab #Preprint alert…A cool study led by @MullickSan22454 in collab with @ms_chirps lab showing how tubulin glycylation regulates ciliary motors and MAPs in vitro. @biorxiv_biochem. #glycylation #tubulinPTMs #cilia #Intraflagellartransport. Read more biorxiv.org/content/10.648…
Thank you for reposting 😀🙌
Sending you virtual hugs ❤️ I recently moved and had to give away some books too. It's so hard to part with them.
New preprint out:
arxiv.org/pdf/2604.01057
Together with JF Joanny and Sudipta, we introduce a "new" kind of active phase separation inspired by experiments with motors and microtubules and based on transport of species along a polar "pump"!
@manuelthery.bsky.social @lblanchoin.bsky.social
🥳 Excited to share our #diatom work out in @pnas.org. In a great collaboration with @nic-poulsen.bsky.social and @ulrichschwarz.bsky.social we show that diatoms modulate the curvature of their paths by dynamic switching of their cell–substrate contact sites.
doi.org/10.1073/pnas.2506122123
Cordula Reuther, Paula Santos-Otte, Stefan Diez and colleagues find that microtubule lattice defects facilitate spastin-mediated severing.
journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
Thank you 🙌😃
🎉 Exciting news!
Our paper has been accepted and is now published in Wiley Advanced Science! 🚀
Congratulations @bucklingmt.bsky.social
Read it here: advanced.onlinelibrary.wiley.com/doi/epdf/10....
Happy to share that the study is now published in Advanced Science 🙌🥳 :
advanced.onlinelibrary.wiley.com/doi/10.1002/...
I want to thank my co-authors and my amazing PI @lauraschaedel.bsky.social for all the help, lovely discussions and encouragement😀
Cool study and some great images 😃😍 Congrats 👏
Thank you so much for finally putting this issue in words. It is really confusing to communicate and even discuss to those within the cytoskeletal field. This needs to happen 🙌🙌
🦁🦁
An intracellular meteor shower. EB3 comets tracking growing microtubule plus-ends in a cultured cell.
Our new preprint is live!🎉
Cytosolic factors govern vimentin network architecture and mechanics. Cytosolic components shape vimentin IF networks & mechanics - beyond minimal reconstitutions.
On bioRxiv now!
Congrats @dyuthisreekumar.bsky.social
www.biorxiv.org/content/10.6...
I loved Scott and Kip in Gamechanger. Happy Reading 🙌🙂
😍😍😍😍
Forgot about this too and my favorite fic updated last night 😭I need to know what happens 😭
Thank you A03 team for all your work🙌🙌
Exciting new preprint from @schaedellab.bsky.social 🔬🧫
Vimentin network architecture and mechanics is mediated by cytosolic regulation.
I can't help but marvel at the beautiful vimentin network images😍😍
I am so happy it's finally out😍😍❤️ Congratulations @dyuthisreekumar.bsky.social 👏🎉
Yes ! Orbital is one of the reads atop my TBR for the next year. So far I have heard only good things about the book. I picked up 'Dear Thief' by chance and wolfed it down in one sitting. So good. Words, such beautiful words ❤️
I am also hardcore Klunatic, so another favorite of mine from this year was the sequel "Somewhere beyond the Sea" by Tj Klune. So good. His new book also comes out in April 2026.
If you don't mind a bit of angst, betrayal, words so heart-wrenchingly perfect that they seem like poetry, you should read 'Dear Thief' by Samantha Harvey.
Paclitaxel induces NM2-dependent cellular contraction independent of microtubule acetylation in live cells
www.biorxiv.org/content/10.6...
Bored over the holidays? Give our new preprint on how #microtubule lattice alteration by taxols can regulate #RhoA #signalling via GEF-H1 a read!
Perhaps a new mechanism of action for taxol #chemotherapeutics during interphase.
www.biorxiv.org/content/10.6...
Happy holidays ✨🎄
PhD Position in Biophysics #ScienceJobs #AcademicSky
📢Internships on cellular nematics!
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
I like this movie, but a friend of mine likes to complain about the obvious stitching artifacts. I'll try harder next time, Michael. Vimentin (orange) and ER (blue) in an overnight acquisition.
😍😍😍
