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Epigenetic Markers of Response to Psychotherapy in Obsessive-Compulsive Disorder Background Cognitive-behavioral therapy (CBT) is a widely used treatment for mental disorders, yet the biological mechanisms underlying its effects, and the factors contributing to response, remain po...

new #preprint: our epigenetic study on psychotherapy response in OCD is available on medRxiv - includes longitudinal analyses and integration with genetic data.

www.medrxiv.org/content/10.6...

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How libraries classified physics preprints before arXiv and set the stage for distinguishing insiders from outsiders - Nature Reviews Physics In a world with ever-growing scientific literature, meaningful classifications are vital to keep on top of the latest results. In this Comment, historian and sociologist Phillip Roth traces the histor...

I'm super thrilled that my Comment on the vital role that #libraries have played in the history of #preprint communication in #physics is now out with @natrevphys.nature.com 🥳🥳🥳 www.nature.com/articles/s42...
(message me if you can't access the article! It's not a preprint 😉)

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Action-specific ensembles of D1- and D2- MSNs control congruent actions.

Action-specific ensembles of D1- and D2- MSNs control congruent actions.

CRN Team Surmeier's new #preprint examines how the striatum encodes specific movements. Using imaging and optogenetics, the study shows that distinct neural ensembles can drive precise ongoing actions, providing insight into movement control and dysfunction.

🔗: bit.ly/4rVPdXJ

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That's what I just published! #preprint #quantumphysics #qag
Derived Galaxy rotation data, after prediction, eliminating the need for exotic particles, also known as dark matter. Lets go!! 🧑🏻‍🔬🧙‍♂️🪄💜🌎

figshare.com/articles/pre...

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Stay tuned: I’ll unpack the preprint in a thread 🧵 next week

#Durotaxis #Mechanobiology #CellMigration #Preprint

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Computer Science and Mathematics  -   Computer Science

Security and Risk Implications of Transformer-Based Large Language Models

Sergey Saburov *

Computer Science and Mathematics  -   Computer Science Security and Risk Implications of Transformer-Based Large Language Models Sergey Saburov *

A #preprint examines the security and risk implications of semantic ambiguity in #LLM systems.

It analyzes vulnerabilities like prompt injection, tool misuse, and expanded attack surfaces in agent-based and RAG architectures, highlighting gaps in existing security frameworks.

👉 buff.ly/oR4MR7P

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New #preprint alert! @bussigio.bsky.social contributed to a work led by Vojtech Mlysnky, Pavel Banas et al, where hydrogen bond fixes for #RNA force field (ghbfix19) were reformulated as more portable Lennard-Jones fixes doi.org/10.64898/202...

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(PDF) Quantifying Exposure of Pacific Salmon and Steelhead to Climate Change in the Fraser River basin PDF | Climate change can affect salmon and steelhead (Oncorhynchus spp.) throughout their anadromous life cycles, yet there have been no assessments of... | Find, read and cite all the research you ne...

Check this #preprint up! Fabulous work by @steph-peacock.bsky.social !!

Quantifying Exposure of #Pacific #Salmon and #Steelhead to #Climate Change in the #Fraser #River basin

www.researchgate.net/publication/...

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a man in a lab coat is wearing sunglasses and a wig ALT: a man in a lab coat is wearing sunglasses and a wig

The feeling of getting super excited because you’re about to finish — and soon preprint — a paper you’ve been working with @shanshuo.bsky.social on for 5 years… indescribable 🥳. #preprint 🌱 #PlantScience #autophagy ♻️ #immunity #proteostasis #ERCStG #theustunlab

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Classical enhancers couple cis-regulatory logic with transcriptional condensates and 3D genome architecture - preLights Inside super-enhancers, a few classical enhancers do the real work

Inside super-enhancers, a few classical enhancers do the real work 💪

Siddharth Singh covers a recent #preprint proposing a hierarchy inside super-enhancers; from the group of Biswajyoti Sahu #UofHelsinki #UofOslo

#preLight ⬇️👀
prelights.biologists.com/highlights/c...

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Excited to share our #preprint showing that #macrophages in the regenerating #zebrafish #heart are shaped by local cardiac-immune microniches, with a fibroblast-to-macrophage signal promoting regeneration over fibrotic repair www.biorxiv.org/content/10.6...
@idrm.ox.ac.uk @oxforddpag.bsky.social

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Mapping Cell Type Heterogeneity Across The Striatum.

Mapping Cell Type Heterogeneity Across The Striatum.

📣 Check out CRN Team Strick's new #preprint building a multi-omic atlas of medium spiny neurons in the macaque striatum. The team identifies two ventral striatum neuron subtypes and links specific cell types to genetic risk for #ParkinsonsDisease and psychiatric traits.

🔗: bit.ly/4lwGLMI

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Spring in full swing in Germany 🌱🌸
…and in our minds too—new ideas, fresh energy, exciting science ahead and soon a new #preprint from @theustunlab.bsky.social #SpringVibes #PlantScience #theustunlab

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Microscopy preprints: bioimage analysis - FocalPlane Microscopy preprints: bioimage analysis - News

Our latest #preprint list focusses on new research in bioimage analysis and data management.

Drop us a message if you have a suggestion for this list, or our lists on new tools and techniques in imaging or applications of microscopy in biology.
focalplane.biologists.com/2026/03/20/m...

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A #preprint examines public agent ecosystems as a new NLP object, where LMs don’t just generate text but also act, coordinate, and leave public traces.

It frames them as language infrastructure and introduces GATE+AERO as analytical lenses.

👉 www.preprints.org/manuscript/2...

#Academicsky #Edusky

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Cellular morphology emerges from polygenic, distributed transcriptional variation #preprint 🧬🖥️🧪

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#ms2lda #pesticide #preprint #github #proudpi #compmetabolomics #metabolomics #massspectrometry #nontargetscreening #bioinformatics | Justin J.J. van der Hooft Great effort by Jonas Dietrich who exploited the new functionalities of #MS2LDA 2.0 and designed a strategy to derive 50 curated spectral patterns from a large set of #pesticide-related reference mass...

#ProudPI in #CompMetabolomics
#nontargetedscreening #NTS #massspectrometry #metabolomics #preprint 😎
www.linkedin.com/posts/jjjvan...

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Structural analysis of VPS13C and CtVPS13α in complex with CaM.

Structural analysis of VPS13C and CtVPS13α in complex with CaM.

CRN Team De Camilli’s new #preprint reveals the near-atomic cryo-EM structure of VPS13C, a lipid transfer protein linked to #Parkinsons 🧬

The study identifies a lipid-transfer-nonpermissive conformation and calmodulin as a regulatory partner.

🔗 bit.ly/4u5KMvJ

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spotLights Ep 18: Anubhav on junctional heterogeneity & epithelial morphospace #science #biology
spotLights Ep 18: Anubhav on junctional heterogeneity & epithelial morphospace #science #biology YouTube video by The Company of Biologists

New spotLights Short!

This episode features #preLighter Anubhav Prakash (@prakash-patterns.bsky.social), who shares some thoughts on his #preprint about junctional heterogeneity & epithelial morphospace. #DevBio

Big story, covered in under 2 minutes 👇
www.youtube.com/shorts/GjyRQ...

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New #preprint: "A mechanical bifurcation constrains the evolution of cell sheet folding in the family Volvocaceae"

arxiv.org/abs/2603.15171

The next chapter in the #Volvox saga: work done by Valens Tribet during his internship in my group.

@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

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Research infra (RI) tends to be nationally run and built on commercial solutions. #Preprint services are heavily based in US and hosted by commercial services- CloudFlare, Google, Amazon are hosting all of those. #RDAPlenary2026 #OpenScience #DefendResearch #academicsky Too many eggs in one basket

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The spiny mouse nigrostriatal pathway degenerates following exposure to 6-OHDA or recombinant mouse αSyn PFFs.

The spiny mouse nigrostriatal pathway degenerates following exposure to 6-OHDA or recombinant mouse αSyn PFFs.

CRN Team Gradinaru’s new #preprint introduces the spiny mouse (Acomys dimidiatus) as a model of #Parkinsons. α-synuclein PFFs triggered widespread pS129-positive pathology and pronounced nigrostriatal degeneration, with marked dopaminergic changes

🔗 : bit.ly/4qS4oR8

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Original post on mastodon.online

Anecdotal information seems to suggest that the cost of posting a #preprint is less than 0.25% of the cost of a typical APC. In other words, publishing in a typical peer reviewed journal is some 400 times more expensive than posting a preprint. Does pre-publication peer review really improve […]

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This is just racketeering, #preprint and be done with it already…

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#RecursiveSystems #ComplexSystems #PhilosophyOfScience #FormalLogic #SystemsTheory #Emergence #SignalInteraction #FormalNotation #RecursiveDynamics #SymbolicSystems #MultiAgentSystems #TheoreticalFramework #Preprint #IndependentResearch #TRISIGIL

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🏆 #PreprintOfTheWeek on #ScienceOpen "Europe's Problem Child : The Turkish Path to Europeanisation"

Congrats from the Editors of ScienceOpen Preprints to the author Andreas Savva.

Discover the full #preprint and join the discussion.
🔗Link in the first comment.
#Turkey #EU

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This will soon be online as #preprint. Collaboratively, our first attempt to understand #tumor #response upon #oncolytic #virus #TVEC #therapy in #melanoma by a brilliant student in our lab

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Also at #preprinthub1, Soham De from the University of Oxford will present a #preprint from Dr. Samuel G. Katzs' lab about the efficacy of nanobody MET CAR-T cells in solid tumours.

www.biorxiv.org/content/10.6...

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Rearrangement of amphipathic helices enables lipid uptake at ATG2A N-terminus.

Rearrangement of amphipathic helices enables lipid uptake at ATG2A N-terminus.

📢 New #preprint from CRN Team Hurley!

The team uncovers the mechanism of ATG2A-mediated lipid transport 🧬

Structural modeling and simulations show that N-terminal helices gate lipid transfer, and a designed mutant transfers lipids three times faster in vitro.

🔗 bit.ly/4rHuWpr

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The global relationship between flowering plant and pollinator diversity…and what they don’t tell you about posting preprints! Last week I posted a preprint on the platform Research Square of a new manuscript entitled “The global relationship between flowering plant and pollinator diversity holds true across scales, …

Last week I posted a #preprint entitled “The global relationship between flowering plant and #pollinator diversity holds true across scales, latitude, and human influence”.

I was not prepared for what happened after it went live on 2nd March! Read more here:

jeffollerton.co.uk/2026/03/12/t...

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