New from our lab @crick.ac.uk, in collaboration with the Enchev and Bukau labs.
By studying a protein that is difficult to fold, we discover fascinating new mechanisms by which the ribosome supports protein biogenesis.
www.biorxiv.org/content/10.1...

#microsky #plasmidsky #phagesky #phage

Thank you for having us onboard!

Great time in Lund to kick off the hands-on phage biology course organized by Vasili @hauryliuk.bsky.social and his team! Fantastic course and a strong line-up of lecturers throughout the week 🧬🧑🏼‍🏫🍿

Promoting ribosomal incorporation of backbone-modifying nonproteinogenic amino acids into nascent peptides by ATP-binding cassette family-F proteins and EF-P url:academic.oup.com/nar/article/53/10/gkaf44...

Prokaryotic ABCF proteins in overcoming ribosomal stalling: mechanisms, evolution, and perspective for applications in Bio-manufacturing Abstract. ABCF proteins (ABCFs) are key components of prokaryotic translation systems, resolving ribosomal stalling. These ATPases contain two ATPase domai

academic.oup.com/bbb/advance-...

Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web.
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...

Diverse phage defence systems define West African South American pandemic Vibrio cholerae Our understanding of the factors underlying the evolutionary success of different lineages of pandemic Vibrio cholerae remains incomplete. Interestingly, two unique genetic signatures define the West ...

Exciting times! Our latest preprint is now live 🤩!
After nearly 16 yrs of running my lab, I truly believe this is one of the most significant contributions we've made. It offers fresh hypotheses about how pandemic Vibrio cholerae spreads globally. Let’s dive in!🧵..1/n
www.biorxiv.org/content/10.1...

Slippery slope

We are scouting for a PhD student in antiphage immunity. Starting spring 2025 at University of Tartu, Estonia, secondments at Lund. Please contact me with i) CV and ii) max 2-page cover letter (why you, why this topic and why our team) at vasili.hauryliuk@ut.ee. RT appreciated!

Ok, let us see if this thing works.

Check out our new paper:

Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in P aeruginosa

This was a wonderful collaboration with Karen Maxwell and Eric Deziel's labs 🇨🇦

doi.org/10.1101/2023...

Hello world!