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Posts by Shellie Fravel, PharmD

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Still ordering hydralazine? 🤔
Beyond case reports, this large cohort compares hydralazine vs ACEi/ARB to estimate real-world vasculitis risk, will this 📉 bias & clarify the answer
Read more 👇
pubmed.ncbi.nlm.nih....

#TenPostNephJC #NephJC
#NephSky #MedSky

1 day ago 6 8 1 1
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Evaluating Long-Term Outcomes Across eGFR Equations in Older Adults The current diagnostic threshold for chronic kidney disease (CKD; estimated glomerular filtration rate [GFR; eGFR] < 60 ml/min per 1.73 m2) may lead to overdiagnosis in older adults. Additionally, no ...

Evaluating Long-Term Outcomes Across eGFR Equations in Older Adults - Kidney International Reports www.kireports.org/article/S246...

1 week ago 1 0 0 0
Announcing the NephJC Editorial Internship — NephJC Are you a curious, motivated nephrology fellow or early‑career faculty member with a passion for science communication? NephJC is inviting a small group of talented individuals to join our Editorial I...

The #ISNWCN has high trial impact clinical trials to celebrate latest and more successful results in our nephro world

To celebrate the joy of getting together, and to #NephItForward, we officially opened up the #NephJC Editorial Internship application

www.nephjc.com/news/nephjc-...

3 weeks ago 5 4 1 0
 

This is figure 1, which shows plastic waste recycling and bio-upcycling strategies.

This is figure 1, which shows plastic waste recycling and bio-upcycling strategies.

A paper in Nature Sustainability presents an approach to upcycle plastic waste through microbial conversion into levodopa, a medicine for Parkinson’s disease. go.nature.com/4ryglvx 🧪

1 month ago 9 3 1 0
Time to Treatment Discontinuation among Apixaban Users and Time to Initiation of Oral Anticoagulation Among Matched Non-Users. Note: OAC – oral anticoagulant. Apixaban users (in red) had filled their first apixaban prescription within 30 days from their new diagnosis with atrial fibrillation. Continued use was present when a subsequent apixaban prescription was filled within no more than 7 days after the most recent supply was exhausted. If no refill occurred, 7 days were added to the most recent days’ supply. Apixaban use also ended when a prescription for a different OAC was filled. Non-users (in blue) of an oral anticoagulant within the same number of days from their new diagnosis with atrial fibrillation as their matched apixaban user were followed for any subsequent initiation of any oral anticoagulant.

Time to Treatment Discontinuation among Apixaban Users and Time to Initiation of Oral Anticoagulation Among Matched Non-Users. Note: OAC – oral anticoagulant. Apixaban users (in red) had filled their first apixaban prescription within 30 days from their new diagnosis with atrial fibrillation. Continued use was present when a subsequent apixaban prescription was filled within no more than 7 days after the most recent supply was exhausted. If no refill occurred, 7 days were added to the most recent days’ supply. Apixaban use also ended when a prescription for a different OAC was filled. Non-users (in blue) of an oral anticoagulant within the same number of days from their new diagnosis with atrial fibrillation as their matched apixaban user were followed for any subsequent initiation of any oral anticoagulant.

Effectiveness and Safety of Apixaban Initiation Following Newly-Diagnosed Atrial Fibrillation in Patients With Kidney Failure on Hemodialysis

bit.ly/44IMgkk

4 weeks ago 0 1 0 0
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CaseHippo One platform for interactive learning, engagement and collaborative knowledge

Still using Cockcroft-Gault for dosing decisions?

This new course examines its limitations and what clinicians need to know as practice shifts to race-free eGFR.

bit.ly/3PQuiYv

#KidneyHealth #Nephrology #ContinuingEducation

4 weeks ago 0 1 0 0
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2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinic... 2026 multisociety guideline for dyslipidemia — lipid management, cholesterol lowering, ASCVD risk reduction, and treatment pathways.

New dyslipidemia guidelines have finally arrived! So much is new & improved compared to prior US guidelines! A broader understanding of lipid risk/reatment (beyond cholesterol), improved thinking about younger adults & lifetime prevention, & so much more! #CardioSky

www.jacc.org/doi/10.1016/...

1 month ago 8 4 0 0
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Shellie Fravel joining from Iowa City. No COI, excited to learn a few things tonight! #nephjc

1 month ago 4 0 0 0
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New Podcast: Dr. McCausland summarizes the main findings from his study on "Effect of finerenone on eGFR slope across different levels of baseline albuminuria and eGFR: Insights from FINEARTS-HF" #ASNCJASN kidney.pub/CPOD0849

1 month ago 0 1 0 0
Original Article | MAR 11, 2026
Finerenone in Type 1 Diabetes and Chronic Kidney Disease (FINE-ONE)
Figure 1. Change in the Urinary Albumin-to-Creatinine Ratio.

Original Article | MAR 11, 2026 Finerenone in Type 1 Diabetes and Chronic Kidney Disease (FINE-ONE) Figure 1. Change in the Urinary Albumin-to-Creatinine Ratio.

In adults with type 1 diabetes and chronic kidney disease with albuminuria, the decrease in the urinary albumin-to-creatinine ratio was significantly greater with finerenone than with placebo. Full phase 3 FINE-ONE trial results: nej.md/4rTPAmu

#MedSky #EndoSky #Nephrology

1 month ago 9 10 1 0
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Use of auto BP devices is rec'd by guidelines but many still measure BP manually. In this preprint, we categorize BP device based on terminal digit (manual BP results in even # terminal digits). Manual BP ~6mmHg lower and associated with 1.16x stroke risk vs automated www.medrxiv.org/content/10.6...

1 month ago 5 3 0 0

This is topic 1b not a 1B graded suggestion, because the data I'm seeing that this is a make believe problem. Further damning of iron by ESA pushers.

#ShowMeTheEvidence
#NephJC

1 month ago 1 2 0 0

Sliding in a little late! Shellie Fravel, pharmacist joining from iowa city. No COI. #nephjc

1 month ago 2 0 0 0
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2026 KDIGO Anemia Management Guidelines — NephJC This week, we will discuss 2026 KDIGO anemia management in patients with kidney disease

#NephSky #MedSky
🩸Blood is thicker than water 🌊
Thankfully we thinned out the 2026 KDIGO Anemia Guidelines for you to peruse.
Come discuss what's new.
Tuesday 2/24/26 at 9pm EST on Bluesky!
Summary by @jeyakumarmeyyappan.bsky.social
www.nephjc.com/news/kdigo-anemia

1 month ago 14 9 0 0
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KDIGO 2026 Anemia in CKD: The Visual Abstract — NephJC Anemia remains a central challenge in chronic kidney disease, influencing quality of life, cardiovascular risk, and clinical outcomes. The updated KDIGO 2026 guideline provides practical recommendatio...

Hey #MedSky #NephSky
KDIGO has updated their guidance on anemia in kidney disease for the first time in a decade! Let's discuss 2/24/26 at 9pm EST
Check out the VA by @shelliefravel.bsky.social
www.nephjc.com/news/2026/2/23/kdigo-2026-anemia-in-ckd

2 months ago 11 8 0 0
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GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD Opportunistic computed tomography (CT)-based screening is the practice of exploiting incidental imaging data for prevention, risk profiling, or presymptomatic detection of relevant disease unrelated…

GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD

bit.ly/3XsLlQY #OpenAccess

2 months ago 0 2 0 0

Shellie Fravel, pharmacist joining from Iowa City, no COI #nephjc

2 months ago 8 0 1 0
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Smartwatch and Hypertension Notification This cross-sectional study assesses the potential impact of a smartwatch hypertension notification feature for US adults who have not been diagnosed with hypertension.

Excited to share our research letter published today in JAMA on the new Apple Watch Hypertension Notification Feature! jamanetwork.com/journals/jam...

1/n

2 months ago 13 8 1 2
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To INFINITI and Beyond: SGLT2 Inhibitors in Kidney Transplant Patients — NephJC This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.

Hey #NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant

2 months ago 9 9 0 1
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Why aren’t you prescribing fish oil to your dialysis patients? PISCES showed a striking cardiovascular benefit with fish oil in hemodialysis. Lovaza closely matches the trial’s ethyl-ester formulation, is FDA regulated, EHR friendly, and offers a practical, re…

PBFluids▶️PISCES showed a striking cardiovascular benefit with fish oil in hemodialysis. Lovaza closely matches the trial’s ethyl-ester formulation, is FDA regulated, EHR friendly, and offers a practical option while we wait for the exact formulation pbfluids.com/2026/01/why-...

2 months ago 11 2 0 1

Up next on #NephJC we will be unpacking SGLT2i in transplant recipients👇

journals.lww.com/cja...

2 months ago 9 4 0 0

Shellie Fravel, pharmacist signing on from Iowa City, no COI #nephjc

2 months ago 7 0 1 0
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🍌🥑Can pushing K⁺ to the high-normal range reduce ICD shocks and hospitalizations?

🎨 #Visualabstract by @jeyakumarmeyyappan.bsky.social

#NephJC chat on Jan 27, 9 pm EST

www.nephjc.com/news/2026/1/...

2 months ago 13 10 0 1
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POTCAST- K+ Pop and Arrhythmia Drop — NephJC This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.

Oh, the weather outside is frightful 🥶🥶
But #NephJC is so delightful,
and since you've no place to go #NephSky...
Come discuss POTCAST: potassium goals and cardiac arrhythmias 1/27/26 at 9pm EST on #Bluesky
Summary by @shelliefravel.bsky.social @salinesolut.bsky.social
www.nephjc.com/news/potcast

2 months ago 13 9 2 1
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Sodium-Glucose Cotransporter-2 Inhibitors #SGLT2i and #Cardiorenal Events in #Nonalbuminuric Kidney Disease

#VisualAbstract by Augusto Cesar S Santos Jr

www.kireports.org/article/S2468-0249(25)00...

@cwhuang0824

3 months ago 3 3 0 0
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Can measuring glomerular filtration finally be easy? Assessment of glomerular filtration rate (GFR) has progressed through a series of practical trade-offs between physiological accuracy and clinical feasibility. Direct measurement of GFR using exogenou...

Can measuring glomerular filtration finally be easy?
#nephsky #nephrology
www.kireports.org/article/S246...

3 months ago 8 2 0 1
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Top Stories in Nephrology 2025 — NephJC 2025 was rich in successful stories. Here are the top 10 that impressed our audience.

It's 2026!🎉
We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST.
Join us on TWITTER (it will always be Twitter to us).
Come on by #NephJC faithful for a lively discussion! You picked & we're count'em down.
www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025

3 months ago 14 13 1 3
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Did we (meaning "you" of course, because you voted) get them right? Is there something missing or is the order wrong? #NephJC #TopTenStories2025
Come discuss with an international cadre of nephrologists & other interested parties on 1/6/26 at 9 pm EST on #Twitter

3 months ago 5 7 0 0

The future of nephrology

4 months ago 2 3 0 0
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1/10

Last #NephJC we discussed dialysis frequency in AKI-D #TenPostNephJC

We sought to answer an age-old question: Is less is really more? Or less is just simply what it is….less?

pubmed.ncbi.nlm.nih.gov/41201895/

4 months ago 8 8 1 0