Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !

I have now read this piece and it is very good.

Massive respect for @merenbey.bsky.social and Iva for their persistence and documenting this torturous process.

Highly recommended reading for anyone who cares about reproducibility in science.

I'm a data scientist @ourworldindata.org and I need help from a botanist or someone local to Kyoto, Japan! 🌸

We present one of the world’s longest climate records: 1,200 years of peak cherry blossom dates in Kyoto.

The researcher who maintained it, Prof. Yasuyuki Aono, sadly passed away last year.

They oversaw a very important social media influence operation for the Kremlin, got caught, fled. And now they're not just back, they're guests at Donald & Melania Trump's Easter Egg Roll at the White House.

I2BC is recruiting group leaders in several disciplines.

Don’t miss the chance to launch your team at Paris-Saclay.

Information : www.i2bc.paris-saclay.fr/wp-content/u...

Applications and enquiries : call2026@i2bc.paris-saclay.fr

Deadline: April 22, 2026

The Garden of Earthly Delights (detail), by Hieronymus Bosch, 1480-1505, 📸 by @alexbrandon

Want to annotate a bacterial genome with structures?

@oschwengers.bsky.social bakta and @gbouras13.bsky.social phold got together, and the result is Baktfold: protein annotation across the microbial tree of life using structures

www.biorxiv.org/content/10.6...

#phagesky #microsky #microbiomesky

Latest from the lab!
Between clinical S. aureus, most gene transfer mechanisms are blocked, yet lateral transduction remains highly efficient.
Restriction modification-defective strains act as gateways for horizontal gene transfer, enabling DNA flow across populations. rdcu.be/fbNQK

Found this to be informative video, that puts things into perspective. Via Max Fisher on Instagram www.instagram.com/reel/DWrsUcU...

Post-translational modifications of GlmR integrate metabolic and stress signals to maintain cell envelope homeostasis in Bacillus subtilis Author summary Bacteria must integrate feedback from multiple metabolic processes and environmental cues to efficiently allocate carbon to produce essential building blocks such as nucleotides, amino ...

🫵 Post-translational modifications of GlmR integrate metabolic and stress signals to maintain cell envelope homeostasis in Bacillus subtilis:

👇👇👇

dx.plos.org/10.1371/jour...

@cdiAMP #subtiwiki

Please Repost 🔄

Global Staphylococcus research community is heading to the Canadian Rockies!

Join the 20th International Symposium on Staphylococci and Staphylococcal Infections
📅 September 20–24, 2026

📍 Banff Centre for Arts and Creativity, Banff, Canada

#ISSSI2026
#Staphylococcus

Mucosal vaccination in mice provides protection from diverse respiratory threats Traditional vaccines target specific pathogens, limiting their scope against diverse respiratory threats. We describe an intranasal liposomal formulation combining toll-like receptor (TLR) 4 and 7/8 l...

Here's the source article

Mucosal vaccination in mice provides protection from diverse respiratory threats

www.science.org/doi/10.1126/...

@atanas-g-atanasov.bsky.social
@princess-vimentin.bsky.social
@tmigratorius.bsky.social
@htina.bsky.social
@dricks.bsky.social
@vet-ingenting.bsky.social

Research Fellow (Postdoctoral) at University of Birmingham Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.

Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com

www.jobs.ac.uk/job/DQY475/r...

95 new Fellows join the European Academy of Microbiology 🔬

The newly elected Fellows represent a wide range of expertise across microbiology and related disciplines , spanning institutions across Europe and beyond.

Read the full announcement📄https://buff.ly/CdRK14U

#MicroSky people, have you ever grown a Staph aureus biofilm that forms a crispy or hard exterior crust (not in urine)? My MBio student Izabela has, and we are not finding much literature on this.

IT IS TIME

The man looked up from his beach chair.

"Really?" He said. "I've only just retired."

Death held up a timer. A single grain was about to fall. And then... It didn't.

CURIOUS

Vetinari shrugged.

"I've only just discovered drinks with little umbrellas. I'll let it fall in a bit" 1/17

Join my campaign to properly fund medical research in Australia 🔬
www.moniqueryan.com.au/medical_rese...

Mapping the yeast atructural interactome with AlphaFold3: an open call for collaboration We are excited to announce the early-stage release of our S. cerevisiae  structural interactome mapping project. Using AlphaFold3 (AF3), w...

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations.
www.evocellnet.com/2026/03/mapp...

Salt supplementation-induced metabolic reprogramming in Streptomyces coelicolor | mSystems Precise control of cellular metabolism is critical to ensure directing cellular resources toward metabolic pathways required for the environment. Many Streptomyces species activate production of secon...

Salt supplementation-induced metabolic reprogramming in Streptomyces coelicolor

#mSystems from @nmouncey.bsky.social

journals.asm.org/doi/10.1128/...

‘Complete joke’: Efforts to reduce funding wait times ends with longer blowout A long campaign to improve Australia’s sclerotic research bureaucracy has culminated in an extraordinary blowout to grant approval times, leaving scientists despondent.

“A complete joke”

After the starting gun fires, Australian researchers have to wait 2–3 years before even starting the race.

Really clear article explaining the impossibly long new time-frames for Australian Research Council grants.

By @liammannix.bsky.social

Predicting protein-protein interactions (PPIs) at proteome scale can take months with co-folding models due to the massive all-vs-all comparisons required.

We are excited to announce FlashPPI, a contrastive learning framework that predicts proteome wide physical interfaces in minutes. 1/🧵

New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

Research Fellow at University of St Andrews Searching for an academic job? Explore this Research Fellow opening on jobs.ac.uk! Click to view more details and browse other academic jobs.

🚨 We’re hiring – MRC-funded Postdoc (3 yrs)

Research Fellow to investigate how mobile genetic elements interact in Staphylococcus aureus and shape gene transfer and pathogenicity.

University of St Andrews
Closes 31 March 2026

www.jobs.ac.uk/job/DQR250/r...

Enquiries: afh22@st-andrews.ac.uk

Radiohead Tells Trump’s Homeland Security to ‘Go F— Yourselves’ After Song Used in ICE Video Radiohead has told DHS and ICE to 'go f--- yourselves' after their song 'Let Down' was used in a video blaming immigrants for violence..

Radiohead has issued a joint band statement decrying the use of the group’s song “Let Down” in a pro-ICE video, telling the U.S.’s Department of Homeland Security to “go fuck yourselves” for misappropriating the track.

Protease-Controlled Prophage Activation in Staphylococcus aureus: New Mechanisms Driving Antimicrobial Resistance and Virulence at University of St Andrews on FindAPhD.com PhD Project - Protease-Controlled Prophage Activation in Staphylococcus aureus: New Mechanisms Driving Antimicrobial Resistance and Virulence at University of St Andrews, listed on FindAPhD.com

📢 Funded PhD in molecular microbiology & phage biology

How do bacterial stress responses control prophage activation and horizontal gene transfer?

Join us at St Andrews to dissect Clp protease–mediated regulation in Staphylococcus aureus.

Apply:
www.findaphd.com/phds/project...

Screenshot of LinkedIn post from ARC saying that DP27 EOI outcomes will be released on RMS on the 26th Feb 2026.

The ARC have said (on LinkedIn) they will release outcomes for Discovery Projects Expressions of Interest (2027) tomorrow👇

Role of staphylococcal EzrA as a molecular organizer of cell division www.biorxiv.org/content/10.64898/2026.02...

Something very different and cool for my lab. Sequencing a 4.4mb TB genome using the Artic-style PCR amplicon method with >5128 primers in two reactions 🤯

Enables culture-free WGS for TB!

journals.asm.org/doi/10.1128/...

Fuck sake.

Basic research on Listeria bacteria leads to unique cancer therapy After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the b...

phys.org/news/2026-02...