Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets Nature Communications - Dysregulation of the T cell compartment is a driving factor in the development of Type 1 diabetes (T1D). Here, the authors present a single-cell gene expression analysis of...

Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩‍🔬 rdcu.be/eXEH6
T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social

Excited to be invited by the #CzechYoungImmunologists to talk about my personal journey in science and my challenges as a PI next week. Looking forward to inspiring discussions with the NextGen of immunologists.
@efis-immunology.bsky.social #immunology

Enjoying the #IUIS2025! Lots of networking and inspiring discussions. Thanks for the excellent organization @iuis-online.bsky.social

Gluten‐Free Diet Induces Small‐Scale Changes Across Multiple T‐Cell Subsets in NOD Mice A gluten-free diet prevents Type I diabetes in NOD mice. We characterized T cells from prediabetic mice on gluten-free or standard diets using flow cytometry and single-cell transcriptomics. A gluten...

Happy to share our study showing the effect of gluten-free diet on T cells in NOD mice! We knew that gluten-free diet prevents diabetes. Now we know that it promotes Treg function and modulates phenotype of NKT cells. @eurjimmunol.bsky.social onlinelibrary.wiley.com/doi/full/10....

Safeguarding the future of biomedical science in the United States NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...

Safeguarding the future of biomedical science in the United States - out in Cell

www.cell.com/cell/fulltex...

Happy to share our newest preprint on #tcells in type 1 #diabetes 👩‍🔬. Thanks to all collaborators and participants! Surprisingly, T cells in T1D including #Tregs were biased towards naive phenotypes: www.biorxiv.org/content/10.1...

Chaos erupts in US science as Trump’s team declares freeze on federal grants The freeze’s effect on research is still unclear, but scientists fear ‘incalculable’ damage.

“It will be much easier to destroy the world’s greatest scientific ecosystem than it will be to try to rebuild it”

Scientists are worried about the long-term effects of the Trump administration’s actions

https://go.nature.com/3PUKeGc