The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of Gαi1/3 to reduce depressive-like behaviors in mice A mitochondrial protein indirectly supports antidepressant BDNF signaling in the brain.

A pathway that acts as an intrinsic antidepressive mechanism in the brain can become disrupted by chronic, mild stress, shows new work that casts light on the neurological and biochemical origins of #depression.

Learn more in #ScienceSignaling: https://scim.ag/4bRVNbG

We close out 2025 with a review by @ananya-p.bsky.social & @tingtingli1.bsky.social in @gutmicrobes.bsky.social discussing the influence of the #microbiota on #gdTcell compartments within the gut, since populations and function differ in the #epithelium and lamina propria. 1/n

The C‐terminal extension of calprotectin mediates zinc chelation and modulates Staphylococcus aureus biomass accumulation Calprotectin (CP) is an S100A8/S100A9 heterodimer that plays an important role in nutritional immunity at the host–microbe interface. CP combats Staphylococcus aureus growth by sequestration of zinc ...

My mentors @vubasicsciences.bsky.social encouraged the #CollaborativeScience behind this work from the Chazin and Skaar labs, with co-author Randy Perera. Excited to have published this work @proteinsociety.bsky.social studying #Calprotectin and #StaphAureus onlinelibrary.wiley.com/doi/full/10....

Worried about microplastics around you. We are excited about utilization of our low cost Raman microscopy tools in identifying microplastic pollution - from human body to California beaches to deep ocean.

Read the story here:
news.stanford.edu/stories/2025...

www.pnas.org/doi/10.1073/...

Grad school is fun! @elenae99.bsky.social the best cake baking buddy anyone could wish for