33rd episode of The Brain Podcast:
Models matter: human-specific roles of POU3F2 and Wnt Signalling in neurodevelopment”
@typlab.bsky.social
I loved being a cohost on this one! Lovely guests and such a great discussion!
open.spotify.com/episode/1sfN...
Congratulations to Dr. Zach Augur, who successfully defended his PhD thesis on Friday!! Zach had an amazing defense which highlighted his incredible productivity in the lab, culminating in 3 first-author publications throughout his thesis work!
Our study “Genetic and proteomic analysis identifies BAG3 as an amyloid‑responsive regulator of neuronal proteostasis" was published in Acta Neuropathologica this week! Congratulations to lead author Zach Augur, who will be defending his thesis later this week!!
link.springer.com/epdf/10.1007...
New TYP lab publication from co-authors
Zach Augur and @garrettfogo.bsky.social
on deciphering the function of Optineurin in iPSC-derived Neurons and Astrocytes! This will be the first of 3 first-author publications from Zach's PhD thesis! link.springer.com/article/10.1...
Huge congrats to @zacharyrmurphy.bsky.social selected as a 2025 Fujifilm Fellow at @harvard.edu 🎉
The Fujifilm Fellowship Program fully funds PhD students doing groundbreaking work in the life sciences!!
New TYP lab publication led by PhD student @alexlish.bsky.social out today in @cp-cellreports.bsky.social! We present a reproducible neuron-astrocyte-microglia tri-culture model to better reproduce intercellular interactions in Alzheimer's disease. Read more here: www.cell.com/cell-reports...
Huge congrats to our Master’s student Emma Karp for receiving the GBM Master Prize from the Society for Biochemistry and Molecular Biology! 🏆🧬
Emma earned it for her work in Biomedical Neurosciences at TUM! 🎓🧠
🔗 gbm-online.de/de/studium-k...
We are proud to celebrate Tracy as the recipient of the Harvard Medical School Clifford Barger Excellence in Mentoring Award! 🎉 Her guidance, encouragement, and dedication mean so much to all of us. Congratulations on this well-deserved honor!
Excited to be back @umasschan.bsky.social for the Boston interactive glial group meeting! So many great talks!
New TYP lab paper out today in @cp-neuron.bsky.social led by PhD student @alexlish.bsky.social! We took a deep dive into the mechanisms underlying CLU in AD using innovative iPSC, mouse, and human data approaches. Be sure to give it a read!
www.cell.com/neuron/abstr...
Congratulations our newly-minted PhD candidate Olivia Pembridge on passing her PQE with flying colors today! Olivia will be using a wide array of iPSC and organoid models to study mechanisms of neurodevelopment!
Truly grateful for the opportunity to share my work at the CSHL Brain Barriers meeting! It’s been amazing to hear about all the exciting and innovative research happening across the community 🧠🚪🩸 #cshlbbb
Congratulations to TYP lab Postdoctoral Research Fellow @heuerwego.bsky.social on being awarded a @brightfocus.bsky.social Alzheimer's Disease Research Fellowship! Sarah is using iPSCs to determine the cellular impacts of ABCA7 mutations in Alzheimer's disease!
Proud of our amazing postdoc @kelliannealexa1.bsky.social who gave a fantastic talk today on her work with neuronal hyperexcitability and modeling blood-brain-barrier dysfunction in Alzheimer's disease today as part of the BWH Neuroscience Seminar Series!
Congrats @alexlish.bsky.social! You should be super proud of the work you’ve accomplished! Can’t wait to see what you do next!
Congrats @zacharyrmurphy.bsky.social!!!
New TYP lab publication out today in Glia, led by talented previous PhD student Hyo Lee! Our first big analysis of induced Astrocytes from 44 individuals in the ROSMAP cohort.
You can find it here: onlinelibrary.wiley.com/doi/10.1002/...
Happy #FluorescenceFriday and inaugural bluesky post- some beautiful microglia-neuron-astrocyte co-cultures from TYP lab postdoc @heuerwego.bsky.social!
The elf has arrived at the TYP lab in style—complete with a sleigh and hippo-reindeer! 🎅🛷 #ElfInTheLab #LabLife #ElvesBehavingBadly
Back in Houston pt. 2!! This time, I had the pleasure to present a poster on Ultra-Rapid ddPCR with my co-first author Emilia Bianchini at SNO 2024. A very fun weekend! #ddPCR #SNO2024
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Now that half of SciTwitter is here…
Come be my colleague!
The Dept of Cell Biology @EmoryUniversity is recruiting a developmental cell biologist.
🔬Do you study mechanisms of development using cell biological (and other) approaches? Join us!🔬
TY for RT!
jobs.sciencecareers.org/job/664684/t...
scientific illustration
📔 New review in Neuropharmacology, "Strategies to dissect microglia-synaptic interactions during aging and in #Alzheimer's disease" by Sarah Heuer, Erik Bloss & Gareth Howell:
🧪🤝🖥️ 🧬 ⑂ #jaxresearch #ScientificResearchPublishing
#alzsky #Neuroscience
doi.org/10.1016/j.ne...
What happens in our brains to bring about such decline and why does it vary so much between individuals? JAX's Erik Bloss, Gareth Howell & Sarah Heuer examined the effects of aging in mouse neurons & synapses, with findings in a new Aging Cell paper #Neuroscience 🧪🤝🖥️ 🧬:
www.jax.org/news-and-ins...
PhD student: "please don't be excited yet, these are just preliminary results, I still need to repeat the experiment multiple times"
PI:
Fluorescence Friday! Ipsc derived endothelial cells (green/ red- tight junction proteins, blue-nucleus) #Bloodbrainbarrier #ipsc #stem #neuroscience
