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Posts by Drug Discovery Unit, University of Dundee

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Inside the University of Dundee’s long‑term fight against Chagas disease - Scottish Funding Council World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. Manu De Rycker shares what his team are doing to combat this disease.

ICYMI yesterday...

Here is @mdr-ddu.bsky.social's blog post on the importance of continuing the fight against #ChagasDisease

#drugdiscovery #GlobalHealth

www.sfc.ac.uk/inside-the-u...

6 days ago 1 0 0 0
An image of intracellular parasites that have been labelled so they are visible.

An image of intracellular parasites that have been labelled so they are visible.

Because in diseases like Chagas, leaving even a single parasite behind isn’t an option.

At DDU, we developed a washout assay to determine if compounds can achieve complete parasite clearance.

#DrugDiscovery #NTD #ChagasDisease #GlobalHealth #ScientificInnovation #NeglectedDiseases #Research

1 week ago 3 2 0 0
One conversation. One shared goal.
 
From a conference in Bolivia to a global collaboration, teams at DDU, the University of Washington, and DNDi are working together to develop new treatments for Chagas disease.

One conversation. One shared goal. From a conference in Bolivia to a global collaboration, teams at DDU, the University of Washington, and DNDi are working together to develop new treatments for Chagas disease.

By bringing together expertise from DDU, @uofwa.uw.edu, & @dndi.org, we’re working to turn scientific potential into real progress against #ChagasDisease.
Tackling #neglecteddiseases takes more than innovation—it takes #collaboration.
#DrugDiscovery #GlobalHealth #WorldChagasday

1 week ago 4 2 0 0
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Inside the University of Dundee’s long‑term fight against Chagas disease - Scottish Funding Council World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. Manu De Rycker shares what his team are doing to combat this disease.

World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. In our latest blog, Manu De Rycker from the @dundee.ac.uk shares what his team are doing to combat this disease.

#ChagasDisease

www.sfc.ac.uk/inside-the-u...

1 week ago 6 5 0 0
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Observed on April 14, World Chagas Disease Day shines a light on a often “silent” but impactful neglected tropical disease: Chagas disease.

Today is a reminder of the importance of addressing neglected diseases and support affected communities.

#WorldChagasDiseaseDay #ChagasDisease

1 week ago 0 1 0 0
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Eliminating vertical transmission of HIV, hepatitis B, syphilis, and Chagas disease - Unitaid

On World Chagas Disease Day, Unitaid highlights the importance of screening for Chagas disease. Too often, people are diagnosed late or not at all. Through SafeStart+, we are integrating screening into antenatal care.

Learn more: https://ow.ly/9Tsa50YI5lH

1 week ago 2 1 0 1
Graphic showing a seated woman with her head down, alongside text reading: “For too long, women have been blamed as a source of Chagas disease.” An icon of the insect vector appears beside her. A red banner at the bottom reads: “It’s time to shift the story.”

Graphic showing a seated woman with her head down, alongside text reading: “For too long, women have been blamed as a source of Chagas disease.” An icon of the insect vector appears beside her. A red banner at the bottom reads: “It’s time to shift the story.”

Today is World #ChagasDisease Day.

For too long, women have been stigmatized for a disease they didn't choose.

Most were infected the same way as everyone else by insect transmission, contaminated food, or other routes.

It's time to replace stigma with support. 🧡

Learn more 👉 bit.ly/4cIYv4I

1 week ago 60 20 0 1
A card announcing the call for papers stating 'Special Issue: The Integrative Biology of Reproduction Guest Editors: Etya Amsalem, Tony D. Williams and Kathryn Wilsterman. Submission deadline: 30 June 2026' with the Journal of Experimental Biology logo and the logo for the Special Issue containing an egg cell surrounded by eight sperm cells. The eighth sperm, on the top right, is penetrating the egg.

A card announcing the call for papers stating 'Special Issue: The Integrative Biology of Reproduction Guest Editors: Etya Amsalem, Tony D. Williams and Kathryn Wilsterman. Submission deadline: 30 June 2026' with the Journal of Experimental Biology logo and the logo for the Special Issue containing an egg cell surrounded by eight sperm cells. The eighth sperm, on the top right, is penetrating the egg.

We are calling for Reviews, Commentaries or research papers for our upcoming Special Issue: The Integrative Biology of Reproduction, covering the entire reproductive process, from mate selection, mating and egg-laying or pregnancy through to parental care

bit.ly/3ZT42hY

2 weeks ago 5 5 0 0
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The Best Weapon Yet Against Sleeping Sickness

Some good news: the most effective drug ever found against sleeping sickness (curative in one oral dose!) is being rolled out:

1 month ago 75 21 0 3
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Microsoft Forms

We're hosting a virtual town hall on 24 Mar, 3-4pm, where our CEO, Professor Sir Ian Chapman, will outline UKRI's upcoming five-year strategy & new mission.

He'll be joined by an executive panel and a Q&A will follow.

Registration closes 23 Mar, 5pm.

Register here⬇️

1 month ago 9 19 0 0
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Drug Discovery Unit Tour and Networking BioDundee is delighted to kick of the year of celebrations for #DDUat20 with Networking and a guided tour of the Drug Discovery Unit.

Want to see what we do up close?
Sign up for the tour and networking event with us and #biodundee. See the link for details and tickets!

#DDUat20

www.eventbrite.co.uk/e/drug-disco...

2 months ago 2 3 0 0

🧪 Throughout the day, we will be posting some of the work that we have accomplished for NTDs in those 20 years. Find out more about our portfolio!

🙏 We thank the many partners we work with, especially those committed to developing new treatments for NTDs.
@dndi.org @wellcometrust.bsky.social

2 months ago 2 0 0 0
DDU at 20 | Founders Sir Michael Ferguson & Alan Fairlamb on Past, Present and Future
DDU at 20 | Founders Sir Michael Ferguson & Alan Fairlamb on Past, Present and Future YouTube video by Drug Discovery Unit Dundee

This is the reason the DDU was established – to support the translation of drug targets into therapeutics. Listen to our founders, Sir Mike Ferguson and Prof. Alan Fairlamb talk about that journey here

www.youtube.com/watch?v=_Skb...

2 months ago 1 0 1 0
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Neglected tropical diseases -- GLOBAL Neglected tropical diseases (NTDs) are a diverse group of 20 conditions that are mainly prevalent in tropical areas, where they mostly affect impoverished communities and disproportionately affect wo...

Today is World Neglected Tropical Diseases Day.
The Neglected Tropical Diseases (NTDs) are a group of diseases that affect >1 billion people worldwide (~1 in 8 people). Despite this number, treatments and diagnostics are often unsafe and unsuitable, if they even exist.

www.who.int/health-topic...

2 months ago 3 2 1 0

🤝 Catering partner sought for Dundee pilot: Nourish Scotland is looking for an experienced hospitality business or organisation for #PublicDiner trial.

🗣️ The project offers a subsidy of £240,000 to local businesses and organisations, plus research and partnership support.
1/2

2 months ago 4 5 1 0
DDU at 20 | Founders Sir Michael Ferguson & Alan Fairlamb on Past, Present and Future
DDU at 20 | Founders Sir Michael Ferguson & Alan Fairlamb on Past, Present and Future YouTube video by Drug Discovery Unit Dundee

As part of our #20thBirthday celebrations, we hear from our cofounders Sir Mike Ferguson and Alan Fairlamb

#ScienceNeverStops

www.youtube.com/watch?v=_Skb...

2 months ago 4 1 0 1
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Hello world! I am excited to announce my lab is open at the University of Utah in the Department of Biochemistry. We are looking for scientists at all levels interested in studying host-virus interactions in both bacteria and animals. Come join us in beautiful Utah! (photo is 10 steps from lab)

2 months ago 74 31 6 0
Video

It's our Birthday!!

2 months ago 4 4 0 0

Science is pretty!

Seems like a great time to find out about the incredible impact that #HenriettaLacks had on modern science!

5 months ago 3 0 0 0
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Target product profile and discovery and development path for novel cryptococcal disease treatments Cryptococcus neoformans and Cryptococcus gattii are World Health Organization critical and medium priority pathogens, respectively. These mainly impac…

Hot off the press: our Target Product Profile to support the development of new medicines to treat #cryptococcal disease:

www.sciencedirect.com/science/arti...

#cryptococcus, #drugdiscovery, #meningitis

@ddu-dundee.bsky.social, @gsk.bsky.social, @dndi.org and many others 🧪

5 months ago 6 4 0 0
Drug Discovery Unit - Dr Manu De Rycker recognised with global honour Dr Manu De Rycker has been named as the newest winner of the WH Pierce Global Impact in Microbiology Prize.

Good morning sky-friends! We have exciting news today!
Our head of biology Dr @mdr-ddu.bsky.social has been awarded the WH Pierce Global Impact in Microbiology Prize by @amiposts.bsky.social as part of their International Horizon Awards

drugdiscovery.dundee.ac.uk/news/dr-manu...

5 months ago 4 2 0 1
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‘Kissing bug’ disease should be treated as endemic in US, scientists say People in at least eight states have been infected with Chagas, new report says, amid low awareness of disease

#Chagas disease remains very neglected, and not only in the US, in spite of an estimated 8 million people being infected with T. cruzi. We, and our collaborators, aim to develop new medicines, but this is becoming increasingly challenging due to lack of funding.

www.theguardian.com/us-news/2025...

7 months ago 2 3 1 0

A reluctance?

7 months ago 1 0 1 0

Good morning Bluesky!
We have reached the end of our UNLEASH meeting and are all preparing to head home.
We are full of enthusiasm and renewed purpose, and we look forward to keeping you all updated on our work!

Tell us - what do you want to know about us?

#SciComm #RNA #Splicing

7 months ago 3 2 0 0
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Good morning Sky-Friends!
Our own @biochemtrix.bsky.social (and occasional poster!) is in Germany at the #Unleash consortium meeting. They are joining us here in the sky @unleash-as.bsky.social so follow along to find out about #AlternativeSplicing!

7 months ago 6 0 1 1

Great opportunity to join our multi-partner collaboration to develop much needed new #antifungal drugs!

#jobs, #drugdiscovery, #Cryptococcus, #Candida

@mrccmm.bsky.social @ddu-dundee.bsky.social @labwyllie.bsky.social @glaxosmithkline.bsky.social

7 months ago 3 2 0 0
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£17.9m research grant to discover new treatments for fungal diseases A team of leading infectious disease scientists from academia and industry have been awarded £17.9 million to identify new drugs to treat fungal infections

Delighted to announce a £17.9 million award from @wellcometrust.bsky.social for the development of new antifungal treatments to a consortium of @ddu-dundee.bsky.social, @labwyllie.bsky.social, @mrccmm.bsky.social and GSK.

#Cryptococcus #Candida #drugdiscovery #antifungal 🧪

tinyurl.com/wywtkpsx

9 months ago 7 3 1 1
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Structure–activity relationships of 1,5-dihydro-2H-benzo[b][1,4]diazepine-2,4(3H)-diones as inhibitors of Trypanosoma cruzi Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi), is responsible for a large health burden with around 6–8 million people infected globally. The current dru...

Great to have a latest #Chagas disease drug discovery paper published in @rsc.org MedChem: pubs.rsc.org/en/content/a...

This work highlights how we decide to progress or terminate series, and hopefully provides some useful approaches and lessons.

@ddu-dundee.bsky.social 🧪 #NTD #drugdiscovery

9 months ago 7 3 1 0
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Wither: The Many Triumphs and Long Fall of Nuclear Physicist Harriet Brooks. Reading the life of Harriet Brooks is like watching the gradual, inevitable unfolding of a horror movie. There's that same idyllic, promising beginning that suddenly gives way as the heroine puts her...

Nuclear physics pioneer Harriet Brooks was born OTD 149 years ago. The discoverer of Nuclear Recoil, the transmutation of elements through radioactivity, and nuclear series, her productive career was brought short by marriage. Here is her story

tinyurl.com/mvcd3ape

#WomenInSTEM #Physics #HistSci 🧪

9 months ago 33 12 0 1
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Principal Scientist - Computational Chemistry (m/f/d)

Opportunity for computational chemist at Syngenta (Stein Switzerland) #CompChem #cheminformatics #ML #AI #agrochem #ChemJobs #chemsky 🧪
jobs.syngenta.com/job/principa...

9 months ago 4 3 0 0