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Posts by @KingOfPathogens

My kids have measles, I can't afford gas, and I'm going to be dead within 2 years now that the CDC cancelled funding for the mRNA treatment that might have save my life. But at least now we have Secretary of War who is a Pulp Fiction fan.

2 days ago 806 117 9 3
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Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy @jci.org
www.jci.org/articles/vie...

3 days ago 10 2 0 0
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Biologists Confirm Not Much Evolution Happened Today STANFORD, CA—Calling it a “pretty slow one” as far as natural selection and genetic drift were concerned, biologists from Stanford University confirmed Tuesday that not much evolution happened today. ...

Except in GCs

theonion.com/biologists-c...

4 days ago 17 6 1 0
Home

events.nyas.org/autoimmune1

5 days ago 0 0 0 0
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@biorxivpreprint.bsky.social The role of integrins in T cell-mediated resistance to Cryptosporidium parvum
www.biorxiv.org/content/10.6... @i3h-upenn.bsky.social @kingofpathogens.bsky.social

5 days ago 5 2 1 0

For those interested in T cell trafficking to the gut - maybe LPAM is not so dominant during enteric infection...
www.biorxiv.org/content/10.6...

5 days ago 1 2 0 0
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This crew....

2 weeks ago 2 0 0 0
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Statistically significant chuckles: who is using humour at scientific conferences? Abstract. We’ve all been there: 11.47, swamped by a long stretch of dense scientific talks at a conference. Six slides into a hyper-technical presentation,

Statistically significant chuckles: who is using humour at scientific conferences? url: royalsocietypublishing.org/rspb/article...

2 weeks ago 0 0 0 0
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Pharmacological reduction of neutrophil infiltration reduces Clostridioides difficile infection severity | mBio Clostridioides difficile remains a leading cause of antibiotic-associated diarrhea worldwide and a major healthcare burden. While antibiotics are commonly used to treat CDI, high antibiotic resistance...

Happy to share this study from the lab led by Orlaith Keenan published in mBio!

Working with an outstanding collaborative team, Orlaith demonstrated that maintaining the right balance of neutrophils is key to limiting severe disease during C. difficile infection. journals.asm.org/doi/10.1128/...

3 weeks ago 6 4 0 0
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Here We Go Sherman Bell GIF ALT: Here We Go Sherman Bell GIF

Watch Director Bhattacharya's performance at CPAC really got to me.

I chose to share some of my observations with him.

Hold on...

1/11

3 weeks ago 322 129 6 21

Ending the war between the US and Iran will be hard, experts say, due to the difficulty of negotiating with a weak, erratic head of state.

3 weeks ago 1021 144 27 7
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A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species Nature Microbiology, Published online: 26 March 2026; doi:10.1038/s41564-026-02311-9Urban-adapted mammals host a wide spectrum of zoonotic viruses, some posing high risks of human infection. These species may act as unmonitored reservoirs for viruses of public health concern.

Out Now! A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species #MicroSky

3 weeks ago 11 6 0 0
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Vaccine Engagement Day 2026 has arrived! 🎉

Let’s come together to #CelebrateVaccines by sharing information and enhancing public awareness about vaccines!🌟

Discover how you can participate: vist.ly/4v2vi

3 weeks ago 8 7 0 1
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Anthony Fauci Delivers Robert R. Marshak Keynote at Penn Vet’s 2026 Institute for Infectious and Zoonotic Diseases Symposium Penn Vet's IIZD brought in experts in infectious disease research for its 2026 symposium and Anthony Fauci, MD, was the keynote speaker.

Awe inspiring talk last week as Fauci reflects on 40 years of the AIDS pandemic. @aai.org www.vet.upenn.edu/anthony-fauc...

4 weeks ago 22 8 0 0
FDA approval of ICOTYDE™ (icotrokinra) ushers in new era for first-line systemic treatment of plaque psoriasis with a targeted oral peptide Johnson & Johnson introduces the first and only IL-23R targeted oral peptide that delivers complete skin clearance and favorable safety profile in a once-daily pill ICOTYDE offers an innovative new option for patients with moderate-to-severe plaque psoriasis to address patients cycling on topical therapies in need of systemic treatment

FDA approval of ICOTYDE™ (icotrokinra) ushers in new era for first-line systemic treatment of plaque psoriasis with a targeted oral peptide

Anti-IL-23R peptide now in oral form! Very successful against psoriasis.

1 month ago 11 5 1 0
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Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist - Nature A fusion protein designed to comprise IL-2 and a helminth-derived TGFβ mimic activates IL-2 and TGFβ signalling pathways in IL-2 receptor-expressing T cells and induces stable antigen-specif...

One for the parasitologists AND cytokine engineers - creative use of a worm TGF to modulate the immune system. www.nature.com/articles/s41...
@cytokinesociety.bsky.social @aai.org @bes-parasitesgroup.bsky.social

1 month ago 2 0 0 0
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“But, as you see, it's a beautiful day, the Strait of Hormuz is open and people are having a wonderful time.”

1 month ago 15820 3588 204 174
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The US slashed research for cancer, Alzheimer’s, mental health — and nearly everything else Revealed in one chart.

Good story from Vox on falling numbers of new and competitive renewal R01 grants.

[Gift Link]

www.vox.com/future-perfe...

1/5

1 month ago 121 65 4 7

Pretti Pretti Pretti Good

Curb your enthusiasm for any change from Trump. While he plays Palestinian Chicken with Bibi—and black swan-eating RFK Jr. gets a pants tent for Cheryl Hines—he's shown Alex Pretti and Rene Good less respect in death than Larry showed Ida Funkhouser.

by Maureen Dowd

1 month ago 295 21 8 3
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Huge shoutout to AAI Public Policy Fellow Tulika Singh, PhD, MPH, for representing the scientific community at PPFP Capitol Hill Day and advocating for increased NIH funding and evidence-based policy. When scientists engage with Congress, we build a stronger future for public health.
#AAIadvocacy

1 month ago 6 2 0 0
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Today was my first outreach session of #BSW26, visiting Broughton C of E Primary school with two new ‘Lovely Lungs’ activities.

This year the theme for science week is CURIOSITY.

KS1 made bubble art lungs
KS2 made inflating lungs

“I LOVE science week” - favourite quote of the day.

1 month ago 8 3 0 0

You put your Vinay in, take your Vinay out, you put your Vinay in and you shake the FDA about.
You do the HokeyVinay and you turn around and that’s what it’s all about.

1 month ago 3 1 0 0
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Exclusive | FDA’s Controversial Vaccines Chief Will Leave the Agency Dr. Vinay Prasad will depart in April, after a year leading the division that approves vaccines and biotech drugs.

Vinay Prasad is leaving FDA (again). www.wsj.com/health/healt...

1 month ago 41 7 3 1
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JCI Insight - CD9 regulates macrophage-mediated remodeling of adipose tissue in obesity

Excited to share new work from our lab in @insight.jci.org 🎉

We find that #CD9 is a key regulator of adipose tissue lipid-associated macrophages #LAMs in obesity. Deleting CD9 improves metabolism in obese mice.

Credit to first author Julia Chini and team!

Read now:
insight.jci.org/articles/vie...

1 month ago 9 2 1 0

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"Our results call for careful reinterpretation of prior studies attributing CNS phenotypes to RORγ-expressing immune cells based on RORγ–Cre–driven genetic models."
#immunology #neuroimmunology

1 month ago 2 2 0 0
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🚨Job alert - please share🚨

Senior Research Fellow (Programme Manager, Neuroimmunology), Trinity College Dublin (TCD), Ireland.
my.corehr.com/pls/trrecrui...
Are you an experienced researcher keen for a unique challenge? Want to help set up and lead a new neuroimmunology research team/lab in TCD...

1 month ago 3 4 1 0
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A $10 million gift establishes the King Center for Lynch Syndrome at the Abramson Cancer Center—the first named center of its kind worldwide. Lynch syndrome affects ~1 in 279 people. The new center will expand lifelong care, research, and education. Learn more: https://bit.ly/4laMCar

1 month ago 1 1 0 0
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The cribriform plate: A dynamic central nervous system immune hub. Review from Collin J. Laaker, Zsuzsanna Fabry and colleagues: rupress.org/jem/article/...

📘 In our #Lymphatics collection: rupress.org/jem/collecti...

1 month ago 5 1 0 0
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Penn Vet Scientists Earn National Honors for Breakthrough Research in Virology and Cancer Innovation Penn Vet's Louise Moncla, PhD, receives Ann Palmenberg Junior Investigator Award; Timour Baslan, PhD, named 2026 Damon Runyon–Rachleff Innovation Award recipient

www.vet.upenn.edu/penn-vet-sci...

1 month ago 8 2 0 0
Dear Director Bhattachaya: I saw your post on "X" with your image doctored with face tattoos to match Mike Tyson with a photo of NIH Director Bhattacharya with tattoos over his eye.

Dear Director Bhattachaya: I saw your post on "X" with your image doctored with face tattoos to match Mike Tyson with a photo of NIH Director Bhattacharya with tattoos over his eye.

Starting my day with an email to Director Bhattacharya (again)...

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2 months ago 47 8 6 1