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Posts by Matthias D'hooghe

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Two weeks ago, Alexandre Bringuet – a Master student @chimieparistechpsl.bsky.social – joined our team for a five-month internship. He will study CO2 capture reactions for the construction of new azaheterocycles, supervised by our PhD student Fien Vanhecke. Welcome Alexandre! @synbioc.bsky.social

5 days ago 1 0 0 0
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Last week, our PhD student Maya Boone presented her work on the preparation of curcuminoid-lanthanide complexes at the 15th Inorganic and Bioinorganic Chemistry Conference in Lisbon πŸ™‚, @synbioc.bsky.social, @fbwugent.bsky.social

1 week ago 0 0 0 0
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Need Pemafibrate? Check out our new route to this PPARΞ± agonist, allowing for the efficient and low-cost preparation of enantiopure Pema at the multigram scale – developed by our PhD student Felien Morlion: dx.doi.org/10.1002/open.... @synbioc.bsky.social @fbwugent.bsky.social

3 weeks ago 0 0 0 0
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Curcumin-based benzothiazepane analogues exhibit selective anti-cancer activity in HCT-116 cells via precipitated particle formation and internalisation Despite extensive investigation into the anti-cancer activity of the natural polyphenol curcumin, its therapeutic application is restricted by its inh…

Our biology paper on curcumin-based benzothiazepane analogs with selective anticancer activity (Prof. Van Camp lab) is now published in Biomedicine & Pharmacotherapy: www.sciencedirect.com/science/arti... @synbioc.bsky.social @fbwugent.bsky.social @crighent.bsky.social @sciencedirect.bsky.social

4 months ago 2 0 0 0
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Our SynBioC PhD student Ulrike Ronse presenting our work related to HDAC6 inhibitor development at the MedChem 2025 meeting in Ghent (Dec. 15th) πŸ˜€ @synbioc.bsky.social @fbwugent.bsky.social @crighent.bsky.social

4 months ago 3 2 0 0
Innovating today for a sustainable tomorrow 
RRB2026 Conference from 1-3 June 2026 in Leuven, Belgium
Quotes from Prof Chris Stevens and Prof Pedro Fardim.

Innovating today for a sustainable tomorrow RRB2026 Conference from 1-3 June 2026 in Leuven, Belgium Quotes from Prof Chris Stevens and Prof Pedro Fardim.

#RRB2026 1-3 June in Leuven
Innovating Today for a Sustainable Tomorrow!
@chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social
Check our latest newsletter mailchi.mp/7e723ddba897...

5 months ago 4 3 0 1

New paper alert πŸ“’ Our review article on lanthanide nucleotide coordination polymers for sensing applications is published in Coordination Chemistry Reviews: doi.org/10.1016/j.cc... @synbioc.bsky.social @fbwugent.bsky.social @elsevierconnect.bsky.social

7 months ago 3 0 0 0
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Our former @synbioc.bsky.social postdoc Goran Poje presenting his research on harmine-curcuminoid hybrids at the EFMC-ASMC 2025 conference in Porto πŸ˜€ @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social

7 months ago 2 0 0 0
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Our @synbioc.bsky.social PhD student Kato Bredael presenting her research on monocyclic Ξ²-lactam antibacterials at the EFMC-ASMC 2025 conference in Porto πŸ˜€ @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social

7 months ago 2 0 0 0
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Our review paper on the synthesis and antibacterial properties of C4-functionalized Ξ²-lactams is published in @wiley.com: doi.org/10.1002/cmdc... @synbioc.bsky.social @fbwugent.bsky.social @chsteven.bsky.social

10 months ago 7 1 0 0
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Our PhD student Ulrike Ronse presenting a decade of work on HDAC6 in our group at the Medicinal Chemistry Frontiers conference 2025 in Chicago πŸ˜€ @synbioc.bsky.social @fbwugent.bsky.social

11 months ago 6 1 0 0
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Check out our new paper on 3-imino-Ξ²-lactam chemistry, published in J. Org. Chem.: pubs.acs.org/doi/full/10....
@pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social
@fbwugent.bsky.social

11 months ago 3 2 0 0
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#SynBioC Proud about our SynBioC team who participated at the Sofico Ghent Half Marathon last Sunday! We love: "Work hard, play hard" @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social

1 year ago 5 4 0 0
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Get to know our enthousiastic SynBioC research group @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social

1 year ago 4 3 0 0
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The varieties of VHL linker experience Or why meticulous experimental and computational characterization are integral to good PROTAC design

New post: I wrote about a recent PROTAC linker design study that drives home the thoroughness with which you have to experimentally and computationally investigate linker flexibility and properties. It's a great role model for practitioners in the field. medchemash.substack.com/p/the-variet...

1 year ago 2 1 0 0
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Sustainable chemistry: producing molecules more environmentally friendly Researchers from the University of Bern and the RIKEN research institute in Japan have made a significant advance in sustainable chemistry. They have succeeded in producing organic molecules through a...

Significant progress in sustainable chemistry: researchers from the #unibern and the RIKEN Institute have been able to produce organic #molecules using a chemical reaction based on the sustainable metals #sodium and #iron: mediarelations.unibe.ch/media_releas... @evaheviagroup.bsky.social

1 year ago 9 5 1 1
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New paper! Our work on cancer cell cytotoxic benzothiazepanes (part 3), in collaboration with the Rega Institute @kuleuven.bsky.social, is published in J. Heterocyclic Chem.: dx.doi.org/10.1002/jhet... @fbwugent.bsky.social @wiley.com #curcumin

1 year ago 3 0 0 0
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New Paper Alert! See our joint SynBioC – VIB-CMB work on #HDAC6 ubiquitin-binding domain inhibitors published in Eur. J. Med. Chem. doi.org/10.1016/j.ej... @elsevierconnect.bsky.social, with @rjharding.bsky.social, KU Leuven, @csbugent.bsky.social, K. Van Hecke. @fbwugent.bsky.social

1 year ago 2 0 0 0
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This #OrgLett cover by Guillermo Correa Otero demonstrates human error in mass spec report checking. Instead use CheckAMM!

Editorial by EIC Marisa Kozlowski introducing CheckAMM:
pubs.acs.org/doi/10.1021/...

What @christmann.bsky.social found checking AMM reports:
pubs.acs.org/doi/10.1021/...

1 year ago 1 2 0 0
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The costs of competition in distributing scarce research funds | PNAS Research funding systems fundamentally influence how science operates. This paper aims to analyze the allocation of competitive research funding fr...

Researchers spend approximately 45% of their time on administrative activities related to #grants rather than actual #research. The current #competition in research #funding has significant drawbacks; evidence-based improvements of the funding system are required: www.pnas.org/doi/10.1073/...

1 year ago 514 232 17 39
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Teambuilding activity at the Christmas market in Ghent πŸ˜€

1 year ago 2 0 0 0
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Congratulations to our new SynBioC doctor Katarina Magdalenic for the excellent work on curcuminoids, and many thanks to Prof. Zrinka Rajic from the University of Zagreb for acting as an external jury member!

1 year ago 0 0 0 0
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It was a pleasure to host Prof. Annette Bayer from the Artic University of Norway today, who gave a very inspiring lecture about stereoselective CO2 fixation and beta-lactamase inhibitor design

1 year ago 0 0 0 0
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