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Posts by Morgan Feeney

Finally published. Many thanks to a wonderful collaborative team and scientific platforms!!! And thanks to editors and reviewers for enthusiasm and a great review.

www.nature.com/articles/s41...

6 days ago 70 29 4 1
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Meet the 2026 Outreach and Engagement Prize Winner, Dr Lindsay Broadbent Ahead of the 2026 Outreach and Engagement Prize Lecture, Swathi Sukumar interviewed Dr Lindsay Broadbent to learn more about her career and how it feels to win a Microbiology Society prize.

Outreach and Engagement Prize winner Dr Lindsay Broadbent presents a lecture on "Science isn’t finished until it is communicated" at 9:00 in the Auditorium. Read more about their work: https://microb.io/4bV2Nps

#Microbio26

1 week ago 13 7 0 0
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Come to #Microbio26 poster 094 to hear all about natural product antimocrobial discovery from @tosinorababa.bsky.social and me #MicroSky

1 week ago 27 8 2 0

I’ll be at poster A038 at #microbio26 - why not pop by for some stickers and bioinformatics chat?

1 week ago 12 3 0 0
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Congratulations from Microbiology Society to the 2026 Prize Medal Winner, Professor Paul Williams!

#Microbio26

1 week ago 11 2 2 0

Each publication in a #Microbio26 journal helps fund 4 student travel grants. Please publish with us if you can!

1 week ago 22 15 0 1
Cross-order detection of bacteriophage transduction in microbial communities using RNA barcoding - Nature Communications Bacteriophages are the most abundant life form on earth and can be applied to eliminate or engineer bacteria. Here, authors demonstrate RNA barcoding as a high throughput tool to measure bacteriophage...

#microsky #phagesky #phage

www.nature.com/articles/s41...

4 weeks ago 11 5 2 0

Happy Birthday!!!

4 weeks ago 0 0 0 0
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Microbial Primer: Ancientbiotics – making modern antimicrobials from historical infection remedies The modern antibiotic era began in the early twentieth century, but humans have long used materials from the natural world to attempt to treat the symptoms of infection. In this primer, we will discus...

Why should microbiologists be interested in historical infection remedies, and how can we best investigate them for antimicrobial discovery? Thoroughly enjoyed co-writing this Microbiology Primer with @tosinorababa.bsky.social www.microbiologyresearch.org/content/jour... #MicroSky #Ancientbiotics

2 months ago 24 13 3 2

Not sure my skills are up to electrical engineering but they are gorgeous micrographs of course! ❤️

2 months ago 1 0 0 0
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Thanks!!! That's super helpful!!!

2 months ago 1 0 0 0

Yes no, explorer cells are great! But possibly a little more complexity than what is needed for what I am trying to do (make a giant model of Streptomyces using yarn)

2 months ago 0 0 1 0

Streptomyces friends! What do we think about the relative width of aerial vs vegetative mycelia? Same, or is one thicker than the other?

2 months ago 1 0 2 0

Good to see this out - new CRISPRi work from the
@ryanfseipke.bsky.social lab/ #microsky #streptomyces

A platform for CRISPRi-seq in Streptomyces albidoflavus

journals.asm.org/doi/pdf/10.1...

3 months ago 12 6 0 0
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tRNA-Mediated Plasmid Stabilization for Antibiotic-Free Applications in Escherichia coli Plasmids are essential tools in molecular biology and biotechnology. In research laboratories, it is common to use antibiotic selection markers to ensure that plasmids are stably maintained in a cellu...

A little Christmas gift for the molecular biology nerds! I love the simplicity of this idea: very useful (and small) plasmid selection system that alleviates the need for antibiotics in molbio and bioprocesses. Elegant work by my former PhD student, lab, and colleagues: doi.org/10.1021/acss...

3 months ago 21 8 2 0

You spend your life learning the natural history of the prokaryotes with all this complex taxonomy and then right when you are so proud of your well earned wisdom all the names change just in time for your brain to be too old to handle it

4 months ago 48 7 7 2

So happy to see Mark recognised for his incredible work. Over a ~40 year career he and his group discovered ECF sigma factors, characterised many key developmental regulators of the Streptomyces lifecycle, and identified new mechanisms of bacterial gene regulation, antibiotic action and resistance.

4 months ago 28 10 3 0
Poster advertising a microbiology virtual escape room

Poster advertising a microbiology virtual escape room

Can you help my final year project student with her research please?

If you are a student, please try her virtual escape room! tinyurl.com/mr88k53k

If you are not a student, please share/repost to help us reach more students!

4 months ago 0 2 0 0
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Lac operon: Two gems from the early days (1|2) by Christoph — When I recently wrote about noise in the basement of the lac operon, I stumbled across two papers in said basement, both of which I – and not only I – consider gems of early molecular biology: 'Isolation of the lac repressor' (Gilbert & Müller-Hill, 1966), and 'The nucleotide sequence of the lac operator' (Gilbert & Maxam, 1973). Here in part 1, I will dust off the lac repressor story a bit to make this gem sparkle again...

Lac operon: Two gems from the early days (1|2)

by Christoph — When I recently wrote about noise in the basement of the lac operon, I stumbled across two papers in said basement, both of which I – and not only I – consider gems of early molecular biology: 'Isolation of the lac repressor'…

4 months ago 18 2 1 1
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Systematic mapping of bacteriophage gene essentiality with HIDEN‑SEQ The constant arms race of bacteriophages and their bacterial hosts has inspired major breakthroughs in biotechnology and shaped phages as fierce predators with great clinical potential to fight multid...

#microsky #phagesky

(Fancy!) transposon-insertion sequencing identifies essential genes in #phage. By @aharms485.bsky.social & Co.

www.biorxiv.org/content/10.1...

5 months ago 20 8 0 0
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Paul A Hoskisson

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production

Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces

www.gla.ac.uk/postgraduate...

please repost

6 months ago 36 56 0 3

Well, both really, but especially the flowers :)

7 months ago 1 0 0 0
Pretty flowers in a mug on a desk

Pretty flowers in a mug on a desk

What a lovely way to brighten up the day!!!

7 months ago 3 0 1 0
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Why You Must Plot Your Growth Data On Semi-log Graph Paper by Elio — Take our word for it. For experiment involving growing cells, bacterial or otherwise, God meant you to pay attention to the conditions of growth. He also meant you to plot the results of a g...

Periodic reminder that growth curves need semi-log plots!

schaechter.asmblog.org/schaechter/2...

7 months ago 1 0 1 0
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Wheelchair Access, Wheelchair Accessible Toilets

Super super super recommend Grace Petrie's Fringe show - two nights left!!! Absolutely brilliant!! www.edfringe.com/tickets/what...

8 months ago 1 0 0 0
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tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa Abstract. Transfer RNA (tRNA) modifications have emerged as critical post-transcriptional regulators of gene expression affecting diverse biological and di

#microsky tRNA modifications in Pseudomonas aeruginosa

academic.oup.com/nar/article/...

8 months ago 5 4 0 0
Evidence supporting the first secondary chromosome in actinobacteria as a hallmark of the Embleya genus Embleya is a genus within the family Streptomycetaceae, a group of actinobacteria with outstanding capacity for production of specialised metabolites and a strikingly complex life cycle. In this work, we sequenced the complete genome of the new species Embleya australiensis MST-11070 and validated the assembly using optical mapping. The genome of E. australiensis MST-11070 consists of a 7.1 Mb linear chromosome and three additional replicons, including a 4.2 Mb linear replicon, EEC1, significantly larger than all previously described secondary replicons from bacteria. EEC1 is typified by its similar composition to the chromosome in terms of GC-content, codon usage and gene functions. It also carries terminal inverted repeats identical to the chromosome. EEC1 is enriched in biosynthetic gene clusters (BGCs), including the only copy of the BGCs for the spore pigment and the surfactant peptide SapB, metabolites essential for the organism's lifecycle. EEC1 contains an origin of replication with at least some chromosomal properties, and its replication is likely to depend on functions provided by chromosomally located genes. Further comparison of Embleya spp. genomes suggests that EEC1-like replicons are conserved across the genus, in contrast to other known large linear extrachromosomal replicons (megaplasmids) in the order. EEC1 is thus a hallmark of the Embleya genus and is central to its evolution within the Streptomycetaceae family. We propose EEC1 as a secondary chromosome, distinct from previously described secondary chromosomes that utilise plasmid-like replication mechanisms (chromids) and the largest secondary replicon reported in bacteria, to date. ### Competing Interest Statement Ernest Lacey is a Founder, Board Member, and the Managing Director of Microbial Screening Technology Pty. Ltd. The authors declare no competing financial interests. Biotechnology and Biological Sciences Research Council, https://ror.org/00cwqg982, BB/P021506/1, BBS/E/J/000PR9790, BB/X01097X/1, BB/M011216/1 Novo Nordisk Foundation, https://ror.org/04txyc737, NNF22OC0078997

Our new preprint is out! EEC1 is a massive 4.2 Mb secondary chromosome from Embleya australiensis. Conserved across Embleya, these are the first replicons of their kind in Actinobacteria and the largest secondary replicons in bacteria identified to-date!

1/6 🦠🧪🧬🔬

www.biorxiv.org/content/10.1...

9 months ago 26 12 4 1

“Changing how many chromosomes your host has?? Phages shouldn’t have that power” — my labmate

9 months ago 6 3 1 0
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Great news - this work is now published!! Big congrats to @yeowjiang.bsky.social - amazing that he mastered cryo-EM and now solved his 2nd set of strs! And kudos to Chee Geng (& Nadege) for non-trivial homogeneous purification of TolQRA!

pubs.acs.org/doi/10.1021/...

#MicroSky #SGBUG 1/4

9 months ago 11 3 1 0
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Host glutathione is required for Rickettsia parkeri cell division and intracellular survival Nature Communications - Rickettsia species are bacterial pathogens that obligately reside in the host cell cytosol. Here, Sun et al. report that Rickettsia use host glutathione as a nutrient source...

I'm excited to share the final version of some fun work from our lab. A few interesting phenotypes - depleting host glutathione causes intracellular Rickettsia to form long chains and get restricted by antibacterial autophagy. Congrats to the team!

urldefense.com/v3/__https:/...

9 months ago 20 3 1 0