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Posts by Martín Estermann

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Community✨
It’s time for nominations in the #PASEDB

Elections will be held on June 1, 2026

To nominate colleagues, or yourself, please email @ischneider.bsky.social at igors@lsu.edu and include:
- History with #PASEDB
- Contributions to #EvoDevo
- Why is running/nominated

3 weeks ago 4 4 1 0
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VSD SOUVENIR ! 🎁

For this 10th edition of the VSD meeting, we designed a special bottle for each one of you ! 🥰

You can get your bottle in front of the Athena room from now on (and as such stay hydrated ) !

Thanks to our VSD23 logo winner Somboon Wankanit 🎉

#VSD26 #souvenirs #crete

4 weeks ago 4 1 0 0

We have also prepared a special conference bingo for you 🎉

You have until Thursday to complete it and the winner will be announced on Friday (with a prize).

Good luck !

@gunes-taylor.bsky.social @martinestermann.bsky.social

4 weeks ago 1 1 0 0
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LatinxDB - Martín Estermann Dr. Martín Estermann: From Argentina to the world

🥁 New Latinx in Dev Bio interview!

From Argentina to the world 🇦🇷🌎🔬 Martín Estermann shares his journey, research, and exciting next step—starting his own lab at the Czech Academy of Sciences. @martinestermann.bsky.social

Read here: sites.google.com/view/latinxi...

#DevBio #LatinxInSTEM #NewPI

1 month ago 3 3 0 0
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PASEDB community 🤩

We are excited to announce our first Research Webinar series called:

⭐️EvoDevo Mondays⭐️

Save the date - April 13

With our amazing speakers @luiza-o-saad.bsky.social and João Francisco Botelho

Session chair Professor Natalia Pabón-Mora

#PASEDB #EvoDevoMondays #EvoDevo

1 month ago 26 15 0 2

1st McKinley Lab grad student’s 1st preprint!
@claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy.

Come for her GORGEOUS images, stay for her incredible discoveries.
www.biorxiv.org/content/10.6...
w/ @akelleher1017.bsky.social

1 month ago 127 33 8 1
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Glycogen and lactate metabolism in mouse fetal Sertoli cells sustain the germ line Estermann and Sheheen et al. identified a metabolic coupling between fetal Sertoli and germ cells in mice, driven by glycogen breakdown and lactate transport through the MCT4/MCT1 shuttle. This intera...

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Huge thanks to all the collaborators who made this work possible! Especially the Capel Lab, our partners in crime in this story!

If you’re interested in metabolism, germ cells, or gonadal development, check out the paper 👇

www.cell.com/cell-reports...

1 month ago 2 0 0 0
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This reveals a metabolic coupling between Sertoli cells and germ cells in the fetal testis.

Sertoli cells break down glycogen → lactate, which is then transported 🚀 to support germ cell survival.

1 month ago 1 0 1 0
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We then tested the lactate shuttle 🚀.

Sertoli cells export lactate through MCT4, which can be imported by germ cells via MCT1.

Blocking this transport phenocopied the glycogen loss: germ cells were reduced ⬇️

1 month ago 1 0 1 0
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When glycogen metabolism was disrupted:

• Testicular lactate levels dropped

• Germ cell numbers decreased ⬇️

This suggested that glycogen in Sertoli cells might be used to support germ cells metabolically.

1 month ago 1 0 1 0
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We tested whether glycogen 🍬is required for Sertoli cell differentiation.

Surprisingly:
❌ Blocking glycogen synthesis does NOT prevent Sertoli cell fate.

So glycogen isn’t needed to specify Sertoli cells.

But something else was happening…

1 month ago 1 0 1 0
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One intriguing observation in mouse embryos 🐭
During sex determination, Sertoli cells accumulate large glycogen stores 🍬 Only between E11.5-E13.5 ⏱️
So… what is this glycogen doing?

1 month ago 1 0 1 0

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Metabolism is increasingly recognized as a driver of developmental processes ⚙️

But during gonadal differentiation, we still know surprisingly little about how metabolic pathways influence cell differentiation and survival.

1 month ago 1 0 1 0
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Glycogen and lactate metabolism in mouse fetal Sertoli cells sustain the germ line Estermann and Sheheen et al. identified a metabolic coupling between fetal Sertoli and germ cells in mice, driven by glycogen breakdown and lactate transport through the MCT4/MCT1 shuttle. This intera...

🚨New paper out in Cell Reports ‼️

www.cell.com/cell-reports...

Why do fetal Sertoli cells store glycogen 🍬 during testis development?

It turns out they are feeding germ cells.

We discovered a previously unrecognized metabolic coupling between Sertoli cells and germ cells in the fetal testis 🧵

1 month ago 9 1 1 1
Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series
Friday, March 13, 2026, 3:00pm - 4:00 pm Eastern Time
Martha Echevarría-Andino (University of Wisconsin-Madison)
Hoxa11/Hoxd11 transcription factors regulate extracellular matrix genes during osteochondral differentiation
M. Fernanda Palominos (University of California, Berkeley)
Novel craniofacial genes linked to extreme jaw evolution in pupfishes revealed by tissue-specific transcriptomics and speciation genomics

Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series Friday, March 13, 2026, 3:00pm - 4:00 pm Eastern Time Martha Echevarría-Andino (University of Wisconsin-Madison) Hoxa11/Hoxd11 transcription factors regulate extracellular matrix genes during osteochondral differentiation M. Fernanda Palominos (University of California, Berkeley) Novel craniofacial genes linked to extreme jaw evolution in pupfishes revealed by tissue-specific transcriptomics and speciation genomics

The next the Ethel Browne Harvey Postdoc Seminar will be held Friday, February 13 at 3 pm Eastern Time with Martha Echevarría-Andino @uwmadison.bsky.social and M. Fernanda Palominos @ucberkeleyofficial.bsky.social. Register today and join us. bit.ly/47QVIEK #SDBPostdocSeminar

1 month ago 19 9 1 2
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Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...

🤩💪 Out now! 3D regulatory hubs in sex determination

With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social

1️⃣ METALoci – explore #3DGenome 🧬
2️⃣ Non-coding region controlling Fgf9 🧩
3️⃣ Meis genes = new key players 🌟

👉 rdcu.be/e5sm2

1/n Bluetorial 👇

1 month ago 65 29 1 2
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LatinxDB - Interviews “The only limit is your imagination”-Dr. Rosa Navarro.

We’re launching our Latinx DevBio interview series 🌎🧬

Our first inspiring conversation features Dr. Rosa Navarro: Leading Developmental Biology research in Mexico.

Read here: sites.google.com/view/latinxi...

Thanks, Dr. Navarro, for sharing your journey and insights with us! #LatinxInScience

2 months ago 15 11 0 2
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Honored to receive the 2026 R.R. Bensley Award in Cell Biology from the @anatomyorg.bsky.social 🏆 Excited to keep exploring how metabolism, genetics, and epigenetics shape gonadal development and cell differentiation 🧬Grateful to my mentors, collaborators, and lab mates who made this possible.

2 months ago 10 1 0 1

👋 Welcome to the official BlueSky account of the #VSD scientific community ! This account was created to 👇

-share official announcements
-highlight scientific content & speakers during the #VSD2026 meeting
- support live discussions and help our community stay connected

1/3👇

2 months ago 6 4 1 0
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For this festive season, I’m sending friends and family something a little different: postcards straight from the microscope. 🔬

Featuring my hiPSC Christmas tree from last year and a hiPSC colony turned into a festive bauble, with wishes for a season that’s festive at every scale. 🎄

4 months ago 18 2 1 0
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Are you going to SICB in Jan2026? I can't but I'll be there in spirit with these plates I am donating for the Division of Invertebrate Zoology Libbie Hyman Auction. Show up and support student travel funds by bidding for them! Featuring #membracids #acoels #cnidarians #rotifers @sicb.bsky.social

4 months ago 40 11 3 1
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🎄 Day 1 of the 24 Days of Development ✨🧬
This study shows how different fixation methods (PFA vs. TCA) change what researchers can visualize in chicken embryos using HCR or IHC. 🔍🐣🔬 doi.org/10.1016/j.yd...

4 months ago 21 7 0 1
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🎄✨ Introducing 24 Days of Development!
Each day we’ll highlight one of 2025’s most influential papers published in Developmental Biology, the official journal of the Society for Developmental Biology.
Follow along! 🧬❄️🌟 #DevBio

4 months ago 31 7 6 6

I can’t believe it’s already been a year! 🎉 Grateful to share this initiative with such an amazing group of Latinx scientists in developmental biology 🙌 More to come! ✨

4 months ago 6 1 0 0
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Beta3-tubulin staining in a whole mount mouse embryo (embryonic day 10) in blue, with neural crest cell derivatives labeled with tdtomato transgene (red).

Beta3-tubulin staining in a whole mount mouse embryo (embryonic day 10) in blue, with neural crest cell derivatives labeled with tdtomato transgene (red).

Happy to report that our recent findings on the innervation of the masseter made the cover of the International Journal of Developmental Biology @isdb.bsky.social .
Early post for #FluorescenceFridays
#DevBio @brchfx.bsky.social 🧪

ijdb.ehu.eus/issue/69/

5 months ago 21 3 1 2
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💚🦴 Fluorescence Friday: Halloween edition! 🎃
This glowing mouse embryo skeleton is serving serious spooky vibes 👻 Who knew bone development could look this eerie and elegant? 💀 Image by @martinestermann.bsky.social
#FluorescenceFriday #SpookyScience

5 months ago 24 6 0 0

Join us for a new zoom series on metabolism and development. This will be a monthly feature with PIs and trainees presenting.
Sign up here (forms.gle/Y8QzucogKKrZ...) to get the Zoom link and join the mailing list.

5 months ago 8 5 0 0

We are thrilled to announce the inaugural Metabolism in Development & Physiology virtual seminar, a new series connecting researchers across all stages & disciplines in metabolism!

🗓 13 Nov 2025, 16:00 CET
🎙 Alexander Aulehla (EMBL Heidelberg), &
🎙 Christopher Bell (Uni of Oxford)

See you there!

5 months ago 16 13 1 5

🚨Excited to kick off our online seminar series on Metabolism in Development and Physiology!

Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells

Please RT! 🙏

5 months ago 16 14 1 0