Join our upcoming PhilInBioMed‑Seminar:
Apr 21 | 5 - 6:30 pm (CET) | virtual on Zoom
Kenneth S. Kendler (Virginia Commonwealth University, USA):
“A Conversation about Major Themes in the Philosophy of Psychiatry”
Further information here: philinbiomed.cnrs.fr/event/philin...
#ESR #VeilleESR
Tribune de la C3N du #CNRS signée par plus de 700 scientifiques (membres du comité national, directrices et directeurs d'unités) pour alerter une nouvelle fois sur les conséquences des coupes budgétaires
c3n-cn.fr/2026/04/10/b...
[Lettre ouverte du Conseil scientifique de la Fondation pour la recherche sur la biodiversité (FRB)]
Présenter l’écologie scientifique comme une opinion est dangereux pour la démocratie
www.fondationbiodiversite.fr/actualite/le...
#ESR #VeilleESR
#Unjoursansfin #Groundhogday (2004-2026)
Bacteria producing PHB harm C. elegans in multiple ways. Top: Model of how bacterially produced PHB affect C. elegans and which mechanisms can be alleviated by nuc-1 knock out. PHB, poly-β-hydroxybutyrate; Dar, deformed anal region. Bottom: Transmission electron micrograph of bioplastic polyhydroxybutyrate granules filling the intestine of C. elegans. Imaged by Gregor Hendricks, PHD at UMass Chan Medical School Electron Microscopy Core.
Some #bacteria polymerize excess carbon into polyhydroxybutyrate (PHB), a biodegradable storage polymer. This study shows that #PHB -producing bacteria kill #Celegans nematodes by disrupting pharyngeal & intestinal function @plosbiology.org 🧪 plos.io/4cFAwDz
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge @labliston.bsky.social @sciimmunology.bsky.social
@babrahaminst.bsky.social @drntombizodwa.bsky.social
www.science.org/doi/10.1126/...
Increased phosphorylated tau (pTau-181) is associated with neurological post-acute sequelae of coronavirus disease in essential workers: a prospective cohort study before and after COVID-19 onset
www.thelancet.com/jo...
1/9
Good RFKjr was challenged on his damaging actions cutting healthcare access, vaccine access and racist statements in congress but does anything happen because of this? www.theguardian.com/us-news/2026...
Scientists are going into politics in the US in increasing numbers. This is a brilliant and much needed trend
🧪
www.nature.com/articles/d41...
Première de couverture du livre de François Héran. Illustration de couverture : Jean-Pierre Gack, Les Passeurs d'horizon 9, acrylique sur toile, 100 x 100 cm, 2026 (Nantes, galerie d'art contemporain Toulouse Lauwers).
Quatrième de couverture du livre de François Héran. Texte complet disponible ici : https://www.college-de-france.fr/fr/editions/lecons-de-cloture/face-immigration-le-savant-et-le-politique-9782722608795-0.
[#Parution] La #leçon de clôture de François Héran “Face à l'immigration, le savant et le politique”, @editionscdf.bsky.social, est disponible en librairie à partir d’aujourd’hui www.college-de-france.fr/fr/editions/... @lecomptoir-fmsh.bsky.social @college-de-france.fr #immigration #sociologie
Super cool papier from Félix and co ! Congrats !
Overview of RB-TnSeq screens. Top left: Schematic for RB-TnSeq screen experimental set-up. Top middle: Pie chart depicting the number of RB-TnSeq screens completed for each category. Top right: Previously published TnSeq fitness with 27ng/mL isoniazid plotted against BarSeq fitness with 25 ng/mL isoniazid. Dotted line represents linear correlation between statistically significant hits from RB-TnSeq with TnSeq. Bottom left: BarSeq fitness (log2 fold change) for sugI (Rv3331) and sugA (Rv1236). Bottom right: Cofitness data for Rv3220c and Rv1626.
Discovery of gene functions in #Mycobacterium #tuberculosis has been slow. This study tests a genome-wide barcoded #transposon library across 95 environmental conditions, providing a rich resource of new gene functions, including metabolic & resistance pathways @plosbiology.org 🧪 plos.io/4vG0mz1
French time, UTC+2
Over two billion years, a fierce battle has raged between bacteria and the viruses that infect them. The resulting evolution has shaped the way our bodies fight disease today. @vcallier.bsky.social reports: www.quantamagazine.org/the-ancient-...
Don't miss the great Ken Kendler who will speak online in our Philosophy in Biology & Medicine Seminar in just one week!
Title: "A Conversation about Major Themes in the Philosophy of Psychiatry"
philinbiomed.cnrs.fr/event/philin...
New from the BJPS Review of Books
Deflating Mental Representation
– Frances Egan
Reviewed by Nico Orlandi
www.thebsps.org/reviewofbook...
#philsci #philsky
The capacity of vaccine induced immunological memory, a stellar open-access review by @profshanecrotty.bsky.social www.cell.com/immunity/ful...
#RESEARCHIGHLIGHT 🚨
Wang et al. investigated the functional role of tumour-associated visceral adipose tissue in regulating colorectal cancer anti-tumour immunity and immunotherapy efficacy.
New pub+project from Alan Love, @kampourakisk.bsky.social & Tobias Uller. “Improving scientific mentoring w/HPS.”
Paper available soon: @royalsocietypublishing.org journal #ProceedingsB buff.ly/XY0algj
Until then, check out buff.ly/8Jv3Osi & consider contributing
#HPS-mentoring-in-biology
The Trump Administration was apparently surprised by, and unprepared for, Iran’s capability to inflict economic pain on the U.S. and its allies, @johncassidysays.bsky.social writes. ttps://www.newyorker.com/news/the-fin...
Trump calls on UK, China, France and others to send ships to keep strait of Hormuz open
Amazingly, Trump was right: Starmer really is the opposite of Churchill.
Churchill begged America to save Britain.
Trump to the UK, 6 March: "We don't need them any longer... We don't need people to join wars after we've already won!"
Trump six days later: Publicly begs for the UK to send warships.
For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell
go.nature.com/4bp0jOy
This is how the world ends, not with a bang but with endlessly giving the world’s most ignorant and self-involved man the benefit of the doubt.
Out today: We discovered new viral proteins that target immune signaling molecules, solely based on their AlphaFold-predicted shapes
www.science.org/doi/10.1126/...
Congrats Nitzan Tal and coauthors! Thank you Kranzusch lab for the fun collaboration!
Linking below previous thread on our findings
This is a fantastic paper with a very creative computational approach, that should inspire many "AlphaFlod-predicted shapes" screens.
Great friday read 📖📖
Figure showing an overview of VEXAS syndrome. The clinical phenotype is expanding and the pathobiology of some manifestations have been elucidated. VEXAS=vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic.
VEXAS syndrome is a newly discovered multisystemic disease affecting most organs.
A Review provides a comprehensive overview of VEXAS syndrome, including the disease's discovery, diagnosis, and treatment: spkl.io/63321AvBXS
Hi everyone, I am preparing a lecture and was thinking of the milestone papers in the field of bacterial immunity.
I was curious which ones would you include ?
Thanks!
