I saw her present this last summer. Incredible work. Your students are lucky!

GLASS CEILING SHATTERED 👏

Marie-Louise Eta becomes the first woman appointed to take charge of a men's first team in Europe's top 5 leagues. She will coach Union Berlin for the rest of the Bundesliga campaign 🇩🇪

Abstract deadline approaching (April 15) for the Midwest DNA Repair meeting.

Join us for an exciting meeting with outstanding science and valuable networking. Register and share. $100 includes meals, networking, and social events.

sites.google.com/view/kumc-mi...

Promotional collage for ‘Evolution in the Community.’ Top image shows a museum-style outreach table indoors with a fossil skeleton display, a smiling presenter behind a Nashville Predators-branded table, and a sign reading ‘Fossil Display.’ Text lists upcoming events: April 11 – Nashville Predators Family Night; April 26 – Nashville Earth Day; November 5 – Biodiversity Day at Adventure Science Center. Bottom image shows two people standing at an outdoor booth under a canopy beside a Vanderbilt Evolutionary Studies banner, engaging with a crowd at a community event.

A sneak peak of one of the pages from the upcoming issue of Evolutionary Studies - the Magazine! Join us for #evolution out in the wild!

Revitalizing actinobacteria research: an urgent response to the antimicrobial resistance crisis - Natural Products and Bioprospecting Abstract The crisis of antimicrobial resistance (AMR) is escalating while the antibiotic pipeline remains stagnant. Our bibliometric analysis of eight decades of literature reveals a critical imbalanc...

Research into filamentous actinomycetes, the antibiotic producers, is in steep decline. Loads of natural products chemistry research worldwide but not much aimed at understanding their biology and ecology. The latter is key to unlocking their specialised metabolism

link.springer.com/article/10.1...

No

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature Cas9 structures explain topology sensing and off-target activation.

1/11 In our story out today in @nature.com , we showcase the molecular mechanisms that enable Cas9 to bind and cleave negatively supercoiled ((-)SC) off-targets! 🧬🧵

🔗 www.nature.com/articles/s41...

#CRISPR #Cas9 #DNATopology #AFM #CryoEM #SingleMolecule #Biophysics

📣 Lanzamos webinario “Choose Europe, Choose Spain”, con Ministerio de Ciencia, Innovación y Universidades y #FECYT. El objetivo es posicionar a España como destino estratégico para el talento científico internacional.
✏️ horizonteeuropa.es/choose-europ...
ℹ️ www.horizonteeuropa.es/espana-impul...

Third first-author and first (co-)corresponding author pre-print from my postdoc!
In which we do a whole-genome transposon screen to determine how replication-transcription conflicts are resolved in Bacillus subtilis.
Check out!
www.biorxiv.org/content/10.6...

Kentucky!

@chiquiesteban.me mi mujer y yo nos hemos venido a pasar el finde a tu tierra!

Ahem.

Also faculty positions.

Annual reminder: if you’ve been accepted to multiple graduate programs and are still deciding, please let the ones you’re definitely not going to know as soon as possible!

-Someone who got into his PhD off the waitlist the day after the deadline

We are looking for outstanding scientists to develop ambitious research programs in molecular and cellular biology, with special interest in multidisciplinary projects and computational biology.More info: www.i2bc.paris-saclay.fr #MolecularBiology
#CellBiology #ComputationalBiology #TeamLeaders#I2BC

Adapted from Axelsson et al. 2013 Fig 2c: Histogram showing the distribution of diploid amylase copy number in wolf (n=35, blue) and dog (n=136, red). Dogs carry more copies of the starch-digesting gene AMY2B than wolves. Additional copies make dogs better than wolves at digesting starchy foods like grains & vegetables.

Dogs evolved to eat your leftovers! Comparing dog & wolf genomes revealed dogs have up to 30 EXTRA copies of the amylase gene (AMY2B) that helps digest starch. This is a key genomic signature of living alongside humans & table scraps for thousands of years 🐕 www.nature.com/articles/nat... #2026MMM

Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n

Cool new preprint from the Merrikh lab, from the awesome brand new Dr, Öykü Şensoy!
www.biorxiv.org/content/10.6...

Today, and everyday, Go Heels

Tampoco está España para tirar cohetes. Comparando los datos de la gráfica con los de este artículo (elpais.com/salud-y-bien...), hay más casos por persona que en EEUU

Discovery of additional ancient genome duplications in yeasts Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

Excited to announce our latest publication in reporting evidence for three (3!) new whole genome duplications (WGDs) in yeasts. Scientists have often wondered why WGD is so rare in fungi, it turns out we may just not have been looking hard enough! 🧪 🍄 🧬
www.sciencedirect.com/science/arti...

Directors

Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...

One of those red cards for Real Oviedo was given to Arsenal legend Santi Cazorla, who came back to his childhood team two years ago!

‘You tried to kill us’: Real Oviedo make emotional return to La Liga Spanish club return to the top flight for the first time since 2001, having dropped several divisions and been saved from oblivion by loyal fans

May I suggest Real Oviedo as your La Liga team? Even if we might go back down to the second division this year. Here is a very good primer on its recent history www.theguardian.com/football/202...

Keep Pounding

Group photo of faculty, trainees, alumni, and staff from the Evolutionary Studies Initiative standing together at the ESI Retreat. The group is arranged in several rows inside an industrial event space with exposed beams and wood floors, smiling toward the camera. A holiday wreath hangs on the wall behind them, and tables with notebooks and coffee cups are visible in the foreground. The photo captures a large, interdisciplinary academic community gathered for a full-day retreat.

Last week, faculty, trainees, alumni and friends gathered for our annual retreat. It was a day of talks, trivia and conversation spanning #evolution, medicine, ecology, and genomics. A great reminder of the interdisciplinary community that makes ESI work. More retreat highlights soon…

Adam Luthman says: it depends. Some answers here: rdcu.be/eUVBj

Extremoduro - Stand by (video clip) YouTube video by CATÁLOGO WARNER EXTREMODURO

Nadie ha cantado mejor sobre el duelo. Joder que tristeza
www.youtube.com/watch?v=K2WP...

Salir YouTube video by Extremoduro - Topic

Hoy se sale, y se bebe. Robe Iniesta, el más grande. youtu.be/3tYVVuv18s0?...

This is where I live! Obviously I can't vote, but I will be looking very expectantly for the results on Tuesday!

Brand new preprint from my lab, showing that TnpB, the ancestor of Cas12, acts as a gene drive in plasmids! And it turns out in conjugative plasmids that it acts as a primitive anti-self defense system, providing a potential link between its transposon effect and becoming CRISPR!