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Posts by Dr Zac Wylde

Maternal nutrient sensing regulates ribosome provisioning to the next generation. Maternal dietary restriction and reduced mTORC1 signaling in the pharynx through the Rag GTPase RAGA-1 regulate the amount of translational capacity deposited into embryos. As a result, progeny of dietarily restricted mothers inherit reduced levels of ribosomal proteins at hatching. Although embryogenesis proceeds normally, larvae begin life with lower translational capacity, leading to smaller size and slower early growth until ribosome levels recover during larval development. The diagram was generated in BioRender.

Maternal nutrient sensing regulates ribosome provisioning to the next generation. Maternal dietary restriction and reduced mTORC1 signaling in the pharynx through the Rag GTPase RAGA-1 regulate the amount of translational capacity deposited into embryos. As a result, progeny of dietarily restricted mothers inherit reduced levels of ribosomal proteins at hatching. Although embryogenesis proceeds normally, larvae begin life with lower translational capacity, leading to smaller size and slower early growth until ribosome levels recover during larval development. The diagram was generated in BioRender.

Animals adjust their #proteome to match the environment, but can the proteome can be propagated #transgenerationally? Elif Cenik explores a @plosbiology.org study showing that maternal nutrient sensing regulates ribosome deposition into embryos. Paper: plos.io/4tMpQJe Primer: plos.io/41qOzGT

1 week ago 3 2 0 0
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The SORTEE guidelines for data and code quality control in ecology and evolutionary biology are now published in the Peer Community Journal!

🔗 peercommunityjournal.org/articles/10....

1 month ago 48 27 1 1
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No evidence for squaring the survival curve: lifespan-extending treatments increase variation in age- at-death Abstract. Geroscience has the goal of extending lifespan through geroprotective interventions. These interventions are typically imparted on groups of indi

New paper out with @tahliafulton.bsky.social and Alistair Senior! A complementary meta-analysis of Ivimey-Cook, Sultanova & Maklakov (2025) where we find that lifespan extending treatments dont square the survival curve.
Longer life ≠ compressed mortality.
royalsocietypublishing.org/rsbl/article...

1 month ago 11 6 1 0

Want to make your code better at running again in the future?

My talk next month will be filled with lots of tips about how to write sharable, reproducible R code and why it's good for science

Hope to see you there!
#rstats 🌏🧪👩‍💻

1 month ago 36 12 0 1
Macro photo of a brown stink bug in face view on a leaf, guarding a tightly-clustered bunch of eggs that are shaped and colored exactly like a full tray of dark beer with foam on top.

Macro photo of a brown stink bug in face view on a leaf, guarding a tightly-clustered bunch of eggs that are shaped and colored exactly like a full tray of dark beer with foam on top.

Finally, the bug is back with a round of the Guinness.

1 month ago 8438 1811 92 90
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BBSRC, NERC and Future Leaders fellowships are fantastic opportunities for ECRs to transition to independence. My institute (IVES) at Liverpool Uni is keen to support applicants (vet/ecol/evol/infection/omics etc.). Get in touch with me (ives.fellowships@liverpool.ac.uk) if you're interested!

2 months ago 1 4 0 0

This sounds like a crazy project, you must fill me in on what you are up to. Sounds super interesting!

2 months ago 1 0 0 0

Whaaat thats wild!

2 months ago 0 0 1 0
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Angry and Alone: How Social Experience Shapes Female Aggression in Flies at Newcastle University on FindAPhD.com PhD Project - Angry and Alone: How Social Experience Shapes Female Aggression in Flies at Newcastle University, listed on FindAPhD.com

We're advertising a PhD project on how social isolation influences aggression in flies. Based at Durham, co-supervised by @clarahowcroft.bsky.social . Despite what the ad says, this is also open to international applicants! Any questions, shoot me a msg! www.findaphd.com/phds/project...

2 months ago 16 22 0 1
COSSEE: Collaboration for Open Science and Synthesis in Ecology and Evolution Explore the Collaboration for Open Science and Synthesis in Ecology and Evolution (COSSEE). Discover groundbreaking research, publications, and opportunities. Learn about open science initiatives and ...

Our lab (www.cossee.org) and (www.i-deel.org) are looking for a postdoc(s) to nominate via this program - www.ualberta.ca/en/graduate-.... If you are a good fit, you contact us asap (snakagaw@ualberta.ca or mnakaga1@ualberta.ca) - our internal deadline for nominations is on 9th Feb. 🚀 🔥 🏃‍♂️‍➡️

3 months ago 6 7 0 0
Canada Impact+ Research Training Awards for Postdoctoral Scholars

Please contact me if you want to be nominated for a postdoc via this scheme - you need to live outside of Canada and I need to do so by 9 Feb (and need to start by March 2027) - www.ualberta.ca/en/graduate-... (I think you do need to have a competitive CV etc)

Please email me if you are interested

3 months ago 14 14 1 2
A graph showing daily temperature anomalies since the 1940s

A graph showing daily temperature anomalies since the 1940s

Not a single day in 2025 was cooler than the 1991-2020 average, on a global scale. @copernicusecmwf.bsky.social

3 months ago 392 310 5 23

Join us in Brittany? One week left to apply for this postdoc position deciphering the mysteries of inbreeding depression...

3 months ago 4 10 0 0
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PhD studentship! Deadline Jan 8th 2026 Cryptic fitness consequences of a selfish X chromosome

If spending some time in the UK is of interest, my lab is advertising a PhD post presently with a deadline of Jan 8th.

For MSc enquiries, email me (see link) and see 2nd post.
mahansonresearch.weebly.com/blog/phd-stu...

1/2

3 months ago 14 10 1 1
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Point of no returns: researchers are crossing a threshold in the fight for funding With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.

Scientific funding is a net negative: "European taxpayers will have spent more on the funding process than on the funding itself, and the scientific ecosystem has been drained"

www.nature.com/articles/d41...

3 months ago 47 26 1 1
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Fast females, slow males: accelerated ageing and reproductive senescence in Drosophila melanogaster females across diverse social environments Abstract. Females and males typically differ in lifespan, patterns of ageing, and reproduction. General explanations for variation in the magnitude of this

Who really lives fast and dies young? In Drosophila, females show faster ageing and reproductive senescence than males across social environments, overturning sexual selection predictions and highlighting social effects on ageing. academic.oup.com/evlett/advan...
@laurenmharrison.bsky.social

4 months ago 15 7 1 0
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Launch of new Canada Impact+ Research Training Awards As announced in Budget 2025 -

New post doc funding opportunity:
Are you outside Canada & interested in a post doc on insects & environment/climate? Our lab studies insect evol & ecol, esp reproduction/sexual selection. Our university seeks a nominee. Let's chat!
nserc-crsng.canada.ca/en/news/laun...

4 months ago 5 6 0 0
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French natural philosopher and mathematician Émilie du Châtelet was born #OnThisDay in 1706. Her 'Institutions de Physique' caused debate throughout Europe, and her translation of Newton's 'Principia Mathematica' is still considered the standard translation in France.

#WomenInSTEM

4 months ago 49 20 0 3
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Transgenerational Epigenetic Inheritance: Twists and turns in the story of learned avoidance Evidence that learned avoidance of a pathogenic bacterium can be transmitted to future generations in C. elegans is growing.

Transgenerational Epigenetic Inheritance: Twists and turns in the story of learned avoidance

Evidence that learned avoidance of a pathogenic bacterium can be transmitted to future generations in C. elegans is growing.

buff.ly/gMbJWcX

4 months ago 11 5 0 0

We have a new postdoc position available in the Promislow lab at the HNRCA at #Tufts in #Boston, to work on the #systemsbiology of #aging in #Drosophila. Come join us! For info on the position and to apply, see promislowlab.org/wp-content/u...

4 months ago 11 16 1 0
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The missing heritability question is now (mostly) answered Not with a bang but with a whimper

"It may be uncomfortable to conclude that a widely used study design has been producing spurious results. But the evidence is in, and telling uncomfortable truths is a part of doing science."

Problems with twin studies.

theinfinitesimal.substack.com/p/the-missin...

4 months ago 38 18 0 3
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Mating systems, coevolution and resistance evolution. at University of Hull on FindAPhD.com PhD Project - Mating systems, coevolution and resistance evolution. at University of Hull, listed on FindAPhD.com

Funded PhD studentship available on the way that mating system affects coevolutionary processes with natural enemies. #ecoevo #sexualselection looking for a great candidate spread the word! www.findaphd.com/phds/project... 🧪

4 months ago 12 8 0 0
 A couple lil pink baby stinkbugs emerging from their eggs onto a plant stem that looks covered in cotton candy.

A couple lil pink baby stinkbugs emerging from their eggs onto a plant stem that looks covered in cotton candy.

BRAND NEW SENTENCE LEVEL RESEARCH

Dinidorid stinkbug females are armed with leg holsters containing cordyceps species that they use to inoculate their egg clusters & grow a fuzzy fungal blankie that excludes parasitic wasps.

There is a LOT going on down there! #虫🌎

www.science.org/doi/10.1126/...

5 months ago 245 79 20 12
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squidSim: a flexible R package for structured and reproducible simulations in Ecology and Evolutionary Biology

Interested in simulating the kind of data that you might commonly find in evolutionary and ecological studies?

Then we have the R package for you - squidSim!!

Check our new preprint:
ecoevorxiv.org/repository/v...

7 months ago 67 34 2 6

The final round this year for international PhD scholarships at Monash are now open (August 31st 2025). Interested in evolutionary ecology, global change, sex differences, and/or infectious disease? Maybe some ecotox together with @bbmwong.bsky.social. Get in touch. There will be Daphnia involved...

8 months ago 10 9 0 0

This is amazing. Scathing but so accurate.

10 months ago 2 0 0 0
Lecturer/Pūkenga - Evolutionary Ecology Click the link provided to see the complete job description.

Two jobs at a wonderful Zoo Dept at the University of Otago - a very high quality of life

otago.taleo.net/careersectio...

otago.taleo.net/careersectio...

please repost and apply!

11 months ago 13 14 0 0
The house fly (Musca domestica). Credit Matt Bertone 2014.

The house fly (Musca domestica). Credit Matt Bertone 2014.

"The house fly is a migrant, and it appears to suffer from an incurable case of wanderlust. The fly is born in a mass of filth, being, according to one philosopher, the resurrection, the reincarnation of man's own dirt and carelessness" - Murvosh & Thaggard 1966 Ann Ento Soc Am. Photo by M. Bertone

11 months ago 2 1 0 0

Been looking at these ARC changes. If they go through - as early as next year - I assume this means DE26 & FT26 will be the last time these schemes run. If that's the case - big decision for people putting in this yr, that's a lot of work for only one chance at the schemes (rather than the usual 3)

1 year ago 9 6 6 1
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.

globalnews.ca/news/9793403...

1 year ago 30083 7855 516 266