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Posts by Daniel Yip, CSci, FRSB

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📢 Beer, Bytes & Biology returns on 3rd December! 🍻

Discussions on DOE, lab automation, assay development, media optimisation, and more.

Featuring:

- Adam Winnifrith, Founder of Ēvolvere Biosciences
- Sanam Ahmad, GSK
- Markus Gershater, Synthace
- Lucy Barnes, CRL

➡️ synthace.com/london-bbb-2...

4 months ago 0 1 0 0
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📢 Beer, Bytes & Biology returns on 3rd December! 🍻

Discussions on DOE, lab automation, assay development, media optimisation, and more.

Featuring:

- Adam Winnifrith, Founder of Ēvolvere Biosciences
- Sanam Ahmad, GSK
- Markus Gershater, Synthace
- Lucy Barnes, CRL

➡️ synthace.com/london-bbb-2...

4 months ago 0 1 0 0

And here's the original paper: www.uniumbioscience.com/wp-content/u...

4 months ago 0 0 0 0
Neurotransmitters trigger defense responses in plants
Neurotransmitters trigger defense responses in plants YouTube video by UW-Madison Campus Connection

We need more of these really cool videos on BlueSky!

Here's the source: www.youtube.com/watch?v=7-3y...

4 months ago 0 0 1 0
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🪴 One leaf gets a drop of glutamate, the whole plant reacts.

Stumbled across this cool video of a calcium wave, captured via fluorescent imaging by Simon Gilroy’s lab.

Great demonstration of how plants propagate internal signalling waves to prime themselves for stress responses.

Science 2018.

4 months ago 2 0 1 0
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🚨 Most teams think media optimisation takes months.

Our Innocent Meat case study shows otherwise.

Just 2 DOE experiments took iPSC media from baseline to +250% cell count.

Planning → execution → validated optimisation in 1 week.

Want the full case study? DM me.

#LabAutomation #iPSC

5 months ago 0 0 0 0

Good night bluesky

5 months ago 0 0 0 0
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🚨 HUGE MS breakthrough! Roche's oral BTK inhibitor fenebrutinib nails Phase III:

✅ RMS: 1st BTKi to beat teriflunomide on relapses (96+ wks)
✅ PPMS: Slows disability ≥ ocrelizumab (120+ wks)
✅ Clean safety, brain-penetrant

#MultipleSclerosis #MS #BTKi #Roche #Neurology

5 months ago 4 1 0 0
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𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵: @novartis.bsky.social GanLum clears malaria in 97% of patients! First new treatment in 20+ years.

It's effective vs resistant strains, blocks transmission.

Huge for 600K+ annual deaths. 👏

#pharmaceuticals #biotech #malaria #pharma #ganlum

5 months ago 0 0 0 0
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Lab automation is essential for biology to progress.

Stop doing things manually and save up to get a robot.

Plus it’s cool to get one of these bad boys in your lab!

#labautomation #robotics #biology #science

5 months ago 0 0 0 0
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💊 Pfizer just announced a ~$10B deal to acquire Metsera, adding an obesity drug to its pipeline after setbacks in its own GLP-1 program. The pharma race for next-gen weight-loss drugs is heating up. #biotech #pharma #obesity #GLP1

5 months ago 0 0 0 0

Dear algorithm, show this to people who are interested in:

> Drug discovery
> Assay development
> Media development
> Lab automation
> Design of Experiments
> Multi-factor experimentation
> Method development
> Discovery biology

5 months ago 0 0 0 0
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Better. Faster. Cheaper.

Assay development teams can achieve this with DoE and lab automation.

More robust assays.
Less reagents used.
Faster iterations.
Automated.

Come find us at ELRIG on Booth 14 and I’ll show you how!

#ELRIG

6 months ago 0 0 0 0

Anyone going to ELRIG Drug Discovery in Liverpool next week? #elrig #elrigdd #drugdiscovery #elrig2025

6 months ago 1 0 0 0

AI isn’t replacing scientists, it’s amplifying their learning.

Wet labs aren’t outdated, they’re becoming smarter, automated, and connected.

If you were at #LabOfTheFuture or #BioTechX, I’d love to hear your thoughts 👇

#AI #DrugDiscovery #LabAutomation #DoE #DigitalTransformation #Biotech #Pharma

6 months ago 1 0 0 0

For this loop to work, get the basics right:

Break data silos → structured, machine-readable data

Automate with intent → reproducible, high-quality experiments

Bridge disciplines → biology + data fluency

Design for learning → DoE & structured experiments

6 months ago 1 0 1 0
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The future of R&D = a bi-directional loop:

💻 AI proposes
🤖 Wet lab experiments (automated)
📊 Data feeds back to improve models

6 months ago 0 0 1 0
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The wet lab isn’t going anywhere, it’s evolving!
AI/ML is here to stay in life sciences, but biology still sets the rules.

AI-driven target prediction, protein design, and in-silico screening are exciting, but they all need one thing that can’t be simulated: real biological data.

6 months ago 0 0 1 0
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I used to design experiments in Excel

🧪 Messy
📊 Manual
🤯 Error-prone

Even automation meant coding plate maps line by line

Biology is complex—experiment design doesn’t have to be.

✅ Auto calc
✅ 1-click scripts
✅ Seamless data

Simplify with Synthace

#labautomation #biotech #pharma #lifesciences

9 months ago 1 0 0 0

sorry mis read it.

9 months ago 1 0 0 0

You don't think AI can be useful in drug discovery?

9 months ago 0 0 1 0
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💊 I think drugs that fail in the clinic also failed in discovery.

We never had a good assay to detect it.

Due to OFAT.

🐢 Slow. Blind. Wasteful.

The scientists did not optimise; they were gambling.

DoE fixes this.

Stop playing roulette with lives.
#drugdiscovery #DoE #biotech #pharma

9 months ago 0 0 0 0
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The Dragonfly Discovery from @sptlabtech.bsky.social an automated liquid dispenser that can be used to run powerful multifactorial experiments.

This is how you generate high-throughput insights.

The future of drug discovery is faster, smarter, smaller. 🧬🤖 #biotech #labautomation #drugdiscovery

9 months ago 1 0 0 0

Any scientists here? 🙋‍♂️

#scientists #biologist #researcher

9 months ago 0 0 0 0

🧪 OFAT is not scientific caution.

It’s a legacy of pipettes and plates.

Today’s complexity demands smarter experiments — and better tools to run them.

Start with the question: “What’s the fastest path to clarity?”

2 / 2

#DoE #Biotech #LabOps

11 months ago 0 0 0 0
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🧬 Most failed drugs weren’t bad ideas.

They were greenlit by weak, noisy, or misaligned assays.

We don’t have a molecule problem.

We have a signal fidelity problem.

And it's costing us billions.

1 / 2

#DrugDiscovery #AssayDevelopment #Biotech

11 months ago 0 0 1 0