📢 Beer, Bytes & Biology returns on 3rd December! 🍻
Discussions on DOE, lab automation, assay development, media optimisation, and more.
Featuring:
- Adam Winnifrith, Founder of Ēvolvere Biosciences
- Sanam Ahmad, GSK
- Markus Gershater, Synthace
- Lucy Barnes, CRL
➡️ synthace.com/london-bbb-2...
Posts by Daniel Yip, CSci, FRSB
📢 Beer, Bytes & Biology returns on 3rd December! 🍻
Discussions on DOE, lab automation, assay development, media optimisation, and more.
Featuring:
- Adam Winnifrith, Founder of Ēvolvere Biosciences
- Sanam Ahmad, GSK
- Markus Gershater, Synthace
- Lucy Barnes, CRL
➡️ synthace.com/london-bbb-2...
And here's the original paper: www.uniumbioscience.com/wp-content/u...
We need more of these really cool videos on BlueSky!
Here's the source: www.youtube.com/watch?v=7-3y...
🪴 One leaf gets a drop of glutamate, the whole plant reacts.
Stumbled across this cool video of a calcium wave, captured via fluorescent imaging by Simon Gilroy’s lab.
Great demonstration of how plants propagate internal signalling waves to prime themselves for stress responses.
Science 2018.
🚨 Most teams think media optimisation takes months.
Our Innocent Meat case study shows otherwise.
Just 2 DOE experiments took iPSC media from baseline to +250% cell count.
Planning → execution → validated optimisation in 1 week.
Want the full case study? DM me.
#LabAutomation #iPSC
Good night bluesky
🚨 HUGE MS breakthrough! Roche's oral BTK inhibitor fenebrutinib nails Phase III:
✅ RMS: 1st BTKi to beat teriflunomide on relapses (96+ wks)
✅ PPMS: Slows disability ≥ ocrelizumab (120+ wks)
✅ Clean safety, brain-penetrant
#MultipleSclerosis #MS #BTKi #Roche #Neurology
𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵: @novartis.bsky.social GanLum clears malaria in 97% of patients! First new treatment in 20+ years.
It's effective vs resistant strains, blocks transmission.
Huge for 600K+ annual deaths. 👏
#pharmaceuticals #biotech #malaria #pharma #ganlum
Lab automation is essential for biology to progress.
Stop doing things manually and save up to get a robot.
Plus it’s cool to get one of these bad boys in your lab!
#labautomation #robotics #biology #science
💊 Pfizer just announced a ~$10B deal to acquire Metsera, adding an obesity drug to its pipeline after setbacks in its own GLP-1 program. The pharma race for next-gen weight-loss drugs is heating up. #biotech #pharma #obesity #GLP1
Dear algorithm, show this to people who are interested in:
> Drug discovery
> Assay development
> Media development
> Lab automation
> Design of Experiments
> Multi-factor experimentation
> Method development
> Discovery biology
Better. Faster. Cheaper.
Assay development teams can achieve this with DoE and lab automation.
More robust assays.
Less reagents used.
Faster iterations.
Automated.
Come find us at ELRIG on Booth 14 and I’ll show you how!
#ELRIG
Anyone going to ELRIG Drug Discovery in Liverpool next week? #elrig #elrigdd #drugdiscovery #elrig2025
AI isn’t replacing scientists, it’s amplifying their learning.
Wet labs aren’t outdated, they’re becoming smarter, automated, and connected.
If you were at #LabOfTheFuture or #BioTechX, I’d love to hear your thoughts 👇
#AI #DrugDiscovery #LabAutomation #DoE #DigitalTransformation #Biotech #Pharma
For this loop to work, get the basics right:
Break data silos → structured, machine-readable data
Automate with intent → reproducible, high-quality experiments
Bridge disciplines → biology + data fluency
Design for learning → DoE & structured experiments
The future of R&D = a bi-directional loop:
💻 AI proposes
🤖 Wet lab experiments (automated)
📊 Data feeds back to improve models
The wet lab isn’t going anywhere, it’s evolving!
AI/ML is here to stay in life sciences, but biology still sets the rules.
AI-driven target prediction, protein design, and in-silico screening are exciting, but they all need one thing that can’t be simulated: real biological data.
I used to design experiments in Excel
🧪 Messy
📊 Manual
🤯 Error-prone
Even automation meant coding plate maps line by line
Biology is complex—experiment design doesn’t have to be.
✅ Auto calc
✅ 1-click scripts
✅ Seamless data
Simplify with Synthace
#labautomation #biotech #pharma #lifesciences
sorry mis read it.
You don't think AI can be useful in drug discovery?
💊 I think drugs that fail in the clinic also failed in discovery.
We never had a good assay to detect it.
Due to OFAT.
🐢 Slow. Blind. Wasteful.
The scientists did not optimise; they were gambling.
DoE fixes this.
Stop playing roulette with lives.
#drugdiscovery #DoE #biotech #pharma
The Dragonfly Discovery from @sptlabtech.bsky.social an automated liquid dispenser that can be used to run powerful multifactorial experiments.
This is how you generate high-throughput insights.
The future of drug discovery is faster, smarter, smaller. 🧬🤖 #biotech #labautomation #drugdiscovery
Any scientists here? 🙋♂️
#scientists #biologist #researcher
🧪 OFAT is not scientific caution.
It’s a legacy of pipettes and plates.
Today’s complexity demands smarter experiments — and better tools to run them.
Start with the question: “What’s the fastest path to clarity?”
2 / 2
#DoE #Biotech #LabOps
🧬 Most failed drugs weren’t bad ideas.
They were greenlit by weak, noisy, or misaligned assays.
We don’t have a molecule problem.
We have a signal fidelity problem.
And it's costing us billions.
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#DrugDiscovery #AssayDevelopment #Biotech