In the (early) pathophysiology of MASLD the LSEC and microvascular alterations are key. Lanifibranor improves LSEC capillarisation and dysfunction! tinyurl.com/x37637j4
#AntwerpHepatology #AntwerpHypothesis @rautoupe.bsky.social @svenfrancque.bsky.social
Is the etiological work-up of #PSVD a one-size-fits-all?
DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".
#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social
📢 First @easlnews.bsky.social CPG on surgery in cirrhosis presented today together with the one on TIPS!
🤝 See you at 10:30 Erlinger Room!
@bavenocoop.bsky.social #LiverSky
Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.
@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social
#Cirrhosis #ACLF #EASL2025"
❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population
#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)
📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social
How do you build&lead a successful research team?
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025
Greetings from the DECISION Investigator Meeting at #EASL2025: Study updates and collaborative discussions with Paolo Caraceni & @rautoupe.bsky.social
#ClinicalTrials #cirrhosis
Good morning!
DECISION coordinator Pierre-Emmanuel Rautou just started the early morning abstract session on #cirrhosis at the #EASLCongress in Amsterdam. You can still join in the Benhamou Room until 09.45am! @easlnews.bsky.social
Next at the DECISION Networking Session at #EASL2025, Theresa Wirtz (UKA) presents scRNA-seq data showing a monocyte subset linked to ACLF risk.
Fascinating translational science in action!
@brunslab.bsky.social ky.social @easlnews.bsky.social ky.social
#scRNAseq #ACLF
Lastly at DECISION's Networking Session, Richard Moreau shares new data: high-throughput omics reveals biomarkers for infection & poor outcomes in cirrhosis.
@inserm.fr @easlnews.bsky.social sky.social
#Metabolomics #Cytokinomics #EASL2025
📢📢 looking for a co-founder (CEO) for an early stage medtech startup‼️
Our goal: bring extracellular vesicles from the lab to the bedside of patients with chronic liver disease.🧪
Find the offer here: www.lesdeeptech.fr/tandem/41693...
Kicking off our #EASL2025 Networking Session with an intro to the DECISION project by coordinator Pierre-Emmanuel Rautou - Let’s talk systems medicine, cirrhosis, and precision care! @rautoupe.bsky.social pe.bsky.social @easlnews.bsky.social ky.social #LiverDisease
Interested in vascular liver diseases and more broadly in liver and vessels?
▶️Join the COST Action EURO-VALDI-NET: www.cost.eu/actions/CA23...
Eligibility criteria there: www.cost.eu/am-i-eligible/
📢📢 looking for a co-founder (CEO) for an early stage medtech startup‼️
Our goal: bring extracellular vesicles from the lab to the bedside of patients with chronic liver disease.🧪
Find the offer here: www.lesdeeptech.fr/tandem/41693...
📢📢 Analysis of 249 patients with MASLD and of 2 rat models:
⚠️Liver endothelial cell (LSEC) capillarisation appears before MASH onset
❌LSEC capillarisation progresses with liver fibrosis and inflammation
✅Lanifibranor improves LSEC function
authors.elsevier.com/sd/article/S...
Tips for managing invasive procedures in patients with cirrhosis 🩸🩸:
➡️What limits of laboratory values❓
➡️How to risk stratify procedures❓
➡️When to stop and restart anticoagulants and antiplatelet agents❓
Find this and more there:
doi.org/10.3350/cmh....
📢📢Interested in vascular liver diseases❓
Check the opportunities for:
✅Short Term Scientific Mission 🧳
Deadline Feb 21
✅Conference Grants
Deadline March 14
➡️ more details there
www.valdig.eu/cost-action-...
@rautoupe.bsky.social provides an update on endothelium-platelet interactions in SLD:
🎯 LSEC capillarisation increases with liver fibrosis in MASLD
🎯 Aspirin improves MASLD
🎯 Likely by inhibiting platelet accumulation and/or platelet EV release
@easlnews.bsky.social #SLDSummit
➡️ Following by Marion Biquard's speech on the measurement of the EV proteins 🧬
@rautoupe.bsky.social @ap-hp.bsky.social @institutcurie.bsky.social
🔬The proteomic aspect of the LIVER-TRACK project was presented by Prof. Laure Elkrief 🩺
@rautoupe.bsky.social @cri1149.bsky.social
🧪The Curie Core Tech team is an essential partner for the proteomics aspect of the RHU LIVER-TRACK project. We are very pleased with their contribution alongside us🙏
@institutcurie.bsky.social @ap-hp.bsky.social @rautoupe.bsky.social
➡️Catlado Schietroma from Abbelight, a partner in the RHU LIVER-TRACK project,has presented the progress of their work in WP3 of LIVER-TRACK🧬🧬
@rautoupe.bsky.social
🙏A big thank you to Prof. Cedric Laouenan🩺 for his insightful presentation during the Livertrack General Assembly! Your contribution was highly appreciated👌
#Livertrack #GeneralAssembly #Gratitude
@hopitalbichat.bsky.social @rautoupe.bsky.social @ap-hp.bsky.social
▶️ A real pleasure to hear Professor Durand Zaleski discuss the medical-economic costs and what will be done in the RHU LIVER-TRACK project 💸💸
Looking forward to the upcoming developments!
#LiverTrack #MedicalEconomics #RHU
@ap-hp.bsky.social @rautoupe.bsky.social @hoteldieuparis.bsky.social
🔝What a pleasure to welcome Professor Annalisa Berzigotti from the University of Bern🇨🇭 for a keynote lecture following our General Assembly. Thank you so much 👏
#Rhu
#Livertrack
#SABmeeting
@rautoupe.bsky.social @ap-hp.bsky.social
🎉 It’s the big day! 🎉
Today is our General Assembly & SAB. We look forward to meet everyone.
#livertrack #SAB #Generalassembly #RHU
@hophenrimondor.bsky.social @rautoupe.bsky.social @institutcurie.bsky.social @sorbonne-universite.fr @upcite.bsky.social @institutcurie.bsky.social
🩺 Professor Rautou, the project coordinator, welcomed the partners to the meeting by giving an overview of the LIVER-TRACK project ▶️
@rautoupe.bsky.social @ap-hp.bsky.social @upcite.bsky.social
🔙 A look back to the fantastic General Assembly of LIVER-TRACK!
🙌 A big thank you to all our partners for being there and to our experts for their valuable insights and availability. Your contributions made it a success! 💡🤝
#LiverTrack #GeneralAssembly
@rautoupe.bsky.social @ap-hp.bsky.social
🚨 T-5 Days until our General Assembly & SAB! 🚨
We can’t wait to see you all and share the latest progress of our project. Exciting times ahead as we welcome our experts to join us and contribute to the discussion! 🔥
Stay tuned for more updates!
#LiverTrack
@rautoupe.bsky.social @ap-hp.bsky.social
