14th Ekiden for the HaploTeam already - I can't believe it. But first since we moved to @igbmc.bsky.social!
The competition between the Haplo and Diplo subteams was tough but as always, great fun and team spirit!

⏰ Only 2 DAYS left for early registration! Join us at #Yeast26 (June 13-17, Pacific Grove, CA) for cutting-edge research in #genetics, #genomics, #disease, #regulation, #systemsBiology, #cellBiology, #lifeCycle, #syntheticBiology, & more. Register by April 16 to save! 🧬 genetics-gsa.org/yeast-2026/

Thanks, Luisa!

Ancestral sequence reconstruction analysis indicates the S1/S2 insertion in the SARS-CoV-2 spike gene likely interrupted a codon Abstract. The genome of the seasonal acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has a 12-nucleotide insertion that produced a furin cleava

New from my lab: Ancestral sequence reconstruction analysis indicates the furin-cleavage-site insertion in the SARS-CoV-2 spike gene likely interrupted a codon

academic.oup.com/ve/article/1...

🌊 Get ready for YGM2026- the ultimate #Yeast genetics experience! World-class science meets Pacific Grove paradise

June 13-17

🏨 Stay on-site: deadline April 8
⏰ Conference registration ends April 22

This is THE meeting you don't want to miss! We'll see you there!
#Yeast26 #Asilomar #YeastGenetics

🎤 Meet the PYFF9 speakers!
Yeast & Fungi Conference 2026 in Valencia (8–11 Sept)

📢 Registration & abstract submission open
🔗 yeastfungi.efbiotechnology.org/home

#Yeast #Fungi #Biotechnology #CallForAbstracts
@pyff-9.bsky.social

#Yeast #Genetics Meeting 2026 is in June - Abstract deadline is TODAY! Submit your abstract, attend the meeting this summer in Pacific Grove, CA at #Asilomar Conference Grounds, a 107-acre protected coastal state park located on the Monterey Peninsula. #Yeast26 #YGM2026 genetics-gsa.org/yeast-2026/

And @groupe-sncf.com to this one 🤣

Mapping the yeast atructural interactome with AlphaFold3: an open call for collaboration We are excited to announce the early-stage release of our S. cerevisiae  structural interactome mapping project. Using AlphaFold3 (AF3), w...

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations.
www.evocellnet.com/2026/03/mapp...

Homepage - Yeast Genetics Meeting 2026 Visit our website to learn more.

📢 Reminder: March 5 is the abstract submission deadline for the Yeast Genetics Meeting. Don’t miss the chance to share your work—submit an abstract and encourage colleagues to attend!
genetics-gsa.org/yeast-2026/

The 2026 GSA Awards: The brightest geneticists combine intellect with excellence in education, research, and mentorship This year’s award recipients bring to the table expertise and leadership that have shaped, and will shape, science for years to come.

Thrilled and honored to be part of the 2026 GSA Award recipient! This honor reflects years of teamwork - huge thanks to everyone who has been part of the #haploteam. Proud to share this with you all! @genetics-gsa.bsky.social
genestogenomes.org/the-2026-gsa...

a headshot of David Botstein

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD.
www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

David Botstein | 1942 - 2026 | Online-Tribute.com David was a beloved husband, father, brother, scientist, teacher, mentor, musician, friend, who touched the lives of thousands. David’s wide-ranging scientific career spanned decades with a legacy o…

Sad to learn that David Botstein has passed away. Few people truly shape how you think and do science, and David was definitely one of them. I had a fun and influential time at Princeton with the Botstein, Kruglyak and co gangs. It shaped the way I do science.
www.online-tribute.com/DavidBotstein

www.biorxiv.org/content/10.6... comparison of commercially available #Saccharomyces #mead yeasts.

Our new preprint w/ @balintnemeth.bsky.social and colleagues compares 13 mead #yeast strains for their phenotype, genome, and presents data on metabolites in experimental mead fermentations.

Finally…

Beyond Mendel: a call to revisit the genotype–phenotype map through new experimental paradigms Abstract. The long-standing notion that genotypes map to phenotypes through simple one gene–one trait relationships continues to shape both research in the

New Perspective!🔥It's fascinating how scientists from different fields but interested in the same question [e.g. genotype-phenoytpe relationship] can have such different perspectives. Here we put in our 2 cents wrt genetic effects being context-dependent, and pheno variation being mostly polygenic

Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

With @litinice.bsky.social, we built a haploid resource from 33 wild Taiwanese Saccharomyces cerevisiae strains — including some of the most genetically divergent Asian lineages — to bring natural yeast diversity into a genetically tractable framework. www.biorxiv.org/content/10.6...

Registration is open for the inaugural GRC conference in the Function of Evolving Systems. Aug 9-14, 2026, Waterville Valley. Truly stellar speaker lineup. Student/postdoc fellowships are available! Please come join us! www.grc.org/function-of-... @joybergelson.bsky.social

New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways
www.biorxiv.org/content/10.6...

Discovery of additional ancient genome duplications in yeasts Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

Excited to announce our latest publication in reporting evidence for three (3!) new whole genome duplications (WGDs) in yeasts. Scientists have often wondered why WGD is so rare in fungi, it turns out we may just not have been looking hard enough! 🧪 🍄 🧬
www.sciencedirect.com/science/arti...

Directors

Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...

From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes - Nature A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable integrative genome-...

✨ Latest exciting story of the group in @nature.com. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how large genomic variations affect trait diversity.
www.nature.com/articles/s41...

📣 #EMBOEvoEco returns in 2026 to uncover the mechanistic foundations of ecological and evolutionary change!

Keynote lectures will spotlight the ecology and evolution of symbiosis.

Submit your abstract for the EMBO Workshop: https://s.embl.org/eae26-01-bl

Abstract submission for #Yeast26 is now open! 🍞🍺

Browse abstract submission topics online and start preparing your abstract today.

Topics include disease models & aging, evolution & population genetics, gene regulation, genomics & systems biology, and more!

Learn more: buff.ly/qotaLne

Flier for conference with list of name of speakers and discussion leaders, Title for conference "Evolutionary Perspectives of Metabolic, Cellular and Genomic Diversity in Fungi", 50th Anniversary Conference Chairs: Bridget Barker & Elaine Bignell. held June 20-21 GRS, June 21-26, GRC. URL https://www.grc.org/cellular-and-molecular-fungal-biology-conference/2026/ and list of speakers names.

2026 is the 50th anniversary of the Cellular and Molecular Fungal Biology GRC. It will be June 21-26, 2026. Consider attending this is a great meeting if you work in the fungal biology field at genetic / genomic / molecular scale. www.grc.org/cellular-and... 🍄🧬🖥️

article from @gillesfischer.bsky.social echoing
www.pnas.org/doi/10.1073/...

Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...

First paper of the year for the HaploTeam, showing how domestication repeatedly reshapes sexual–asexual life cycle trade-offs in yeast, and revealing convergent evolution. Huge kudos to the team, brilliantly led by Jing Hou!
www.pnas.org/doi/10.1073/...

Yeast Genetics Meeting abstract submission and registration sites are open! Abstract submission and registration for the 2026 Yeast Genetics Meeting are now open! Present at this premier meeting for students, postdoctoral scholars, research staff, principal investigators, and...

#Yeast #Genetics Meeting abstract submission and registration sites are open! Abstracts due March 5!

community.alliancegenome.org/t/yeast-gene...