Ocular delivery of different valosin-containing protein (VCP) inhibitory formulations prevents retinal degeneration in rho∆I255 mice Rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP) is a progressive inherited retinal degenerative disorder currently lacking effec…

Happy to share our new article in Journal of Controlled Release on the protective effect of VCP inhibition on retinal degeneration

Congratulations to our student Bowen Cao for her excellent work, and many thanks to all coauthors for the great collaboration.

www.sciencedirect.com/science/arti...

Retina in a Dish: Advanced Ex-Vivo Methods for Retina Research The active representation of the Institute for Ophthalmic Research in Tübingen, represents the strategic focus on retina physiology and disease mechanisms, as well as its commitment to training the ne...

For PhD studs, postdocs.
Cutting-edge retina research, from physiology to disease mechanisms. Strong involvement from IOR in Tübingen, highlighting commitment to training the next generation of vision scientists!
@blanka-g.bsky.social @unituebingen.bsky.social

www.eye-tuebingen.de?tx_news_pi1%...

FEBS Advanced Lecture Course “Retina in a dish: Methods & Applications in Life Sciences”.
Co-organized with @Henri Leinonen (Main Organizer) and @Petri Ala-Laurila.
PhD students and postdocs are encouraged to apply!

Safety and neuroprotective efficacy of the VCP inhibitor ML240 in large-animal and human retinal explants: a preclinical ex vivo study - BMC Medicine Background Retinal degenerative diseases represent a complex global health problem due to their significant impact on patients’ daily lives and their highly heterogeneous pathogenesis, which challenge...

Excited to share that our research is now published!
Huge congrats to Ana C. Almansa García, and many thanks to Marius Ueffing, Angela Armento, and all co-authors!
🔗 link.springer.com/article/10.1...
@eye-tuebingen.bsky.social
#Proteostasis #VCP #RetinalDegeneration #PreclinicalResearch