We’re hiring a Junior Group Leader - AI in immunotherapy - to join our team at the earliest possible date. The position is embedded within my Chair and the Chair of Cellular Immunotherapy (Michael Hudecek), and connected to CAIDAS center for AI.
med.uni-wuerzburg.de/fileadmin/03...
2nd call for postdoc positions in the lab. Get in touch for more information or simply apply here: mbg.au.dk/en/news-and-...
❗️5 days left to apply for a PhD position in our group👇
Passionate about transcription?
🚀 We’re recruiting a PhD student in Transcriptional Regulation at @ucph.bsky.social Start Summer 2026
Work with RNA, CRISPR, sequencing & proteomics in the Gregersen Lab @cgen2025.bsky.social
Meet us: gregersenlab.com
Apply by Apr 10, 2026👇
tinyurl.com/PhD-CGEN
The Vlaming lab continues to grow!
It's an exciting time in the Vlaming lab: we've just had our 2nd PhD student join, and the 3rd is joining in February. Now, we're looking to recruit a postdoc!
Great talk yesterday by @hilgerslab.bsky.social on RNA complexity in the nervous system @cgen2025.bsky.social @ucph.bsky.social mRNA isoform regulation occurs at multiple levels, with crosstalk between start and end of mRNA transcripts and serves a critical role to safeguard neuronal gene expression
Thank you to collaborators Gertrud Hjortø, @tcr-miller.bsky.social, and @jzylicz.bsky.social and support from colleagues at cgen2025.bsky.social
What is the function of the RNAPII-interacting SCAF proteins?
In our latest work, led by Smaragda Kompocholi, we show that SCAF1 shapes mRNA isoform expression during neuronal differentiation 🧬 🧠
Loss of SCAF1 → shorter transcripts
📄 Interested in the full story? www.biorxiv.org/content/10.6...
A chance to join Fena’s group @fenaochs.bsky.social @cgen2025.bsky.social! Great lab and center - plus you will become our neighbour😉
Thank you to everyone involved and support from colleagues at @cgen2025.bsky.social and @ucph.bsky.social
Key takeaways:
🔍 Oxidative damage causes an instant shutdown of transcription, but unlike UV, without RNAPII degradation
🔍 Stalled RNAPII resumes transcription from within the gene body
🔍 PARylation controls early elongation restart
🔍 BER and SSBR repair enable RNAPII recovery in the gene body
This beautiful work, led by Quentin Thomas, revealed a surprising spatial organization of the transcriptional response:
🔬 Promoter regions: PARylation governs early RNAPII release
🔬 Gene body: DNA damage and repair drive RNAPII stalling
What happens to transcription upon oxidative DNA damage? 🧬💥
RNAPII halts instantly within genes ⛔️ and even more surprisingly: It restarts from where it stopped without leaving the DNA template 🚦
👀📄 How does this happen? Find out in our new preprint👇 www.biorxiv.org/cgi/content/...
Huge thanks to our amazing team and members within @cgen2025.bsky.social for fruitful discussions 🙌
What did we find? ✅ Elongation rates vary between genes ✅ …and within genes ✅ Histone marks & elongation factors correlate with rate subclasses
Existing methods either rely on indirect estimates or are limited to a handful of long genes. So we built DRB/TTchem-seq2: Short timepoint sampling, new computational framework 📈 leading to a ~7 fold increased individual gene elongation rates measurements!
Interested in measuring RNAPII elongation rates? We developed DRB/TTchem-seq2 to directly measure rates across 3,000+ genes 🧬
genome.cshlp.org/content/earl...
This fantastic work led by Haiyue Liu reveals gene and intra-genic variation, links to histone marks & elongation factors
Details below! 👇
Such a beautiful example of how tight control of transcriptional activity is achieved and even more important: plays a crucial developmental role. Congratulations @jzylicz.bsky.social and team!
❗️One more week to apply for a PhD position in our group👇
Another chance to join our group! Center for Gene Expression has 2 or more postdoc positions @ucph.bsky.social in wonderful Copenhagen. Want to join our team to work on transcriptional regulation? More information at: gregersenlab.com Deadline March 18. Apply here: jobportal.ku.dk/phd/?show=16...
We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...
Postdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...
We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.
New postdoc opportunity in the THJ lab! Please share to anyone interested in nuclear RNA biology
@molbiolau.bsky.social
mbg.au.dk/en/news-and-...
Now official: We have another opening for a fully funded #PhDposition in the Beusch lab (www.beuschlab.org) at @uniwuerzburg.bsky.social! More details here: tinyurl.com/947xcw85 If you or someone you know is curious about #splicing please apply or contact me for more information! #RNAsky #RNAbiology