Enhanced genetic fine mapping accuracy with Bayesian Linear Regression models in diverse genetic architectures Author summary Understanding which genetic variants influence complex traits and diseases is essential for gaining biological insight and developing new treatments. However, large-scale genetic studie...

🧬 New in PLOS Genetics!
We show how Bayesian Linear Regression models can powerfully fine-map genetic variants underlying complex traits & diseases — matching state-of-the-art methods on both simulated & UK Biobank data.
📄 doi.org/10.1371/journal.pgen.1011783

#Genomics #FineMapping #UKBiobank

🚨 JOB POSSIBILITY 🚨
We launching a new AI-health data initiative and hiring 3 tenure track assistant professors.

I’m seeking one in AI-driven statistical genomics 🧬

🔗 www.vacancies.aau.dk/scientific-p...

Please share

#Genomics #StatisticalGenetics #PrecisionMedicine #ComplexTraitGenetics #PopGen

Proud to share that our research group, Genomic Medicine, has contributed… | Palle Duun Rohde Proud to share that our research group, Genomic Medicine, has contributed to a recent study investigating the potential mechanisms underlying pregnancy loss. While chromosomal abnormalities are well-...

The genetics of pregnancy loss 🧬⬇️

www.linkedin.com/posts/palle-...

Today at #eshg2025 in Milan (@eshg.bsky.social) I'm presenting our novel Bayesian polygenic prioritization method, Bayes PoPS.

If you're interested, please visit poster P17.072.A at 13:00

#eshg #genomics #StatisticalGenetics #PrecisionMedicine #ComplexTraitGenetics #eshg2025 #genetics

Postdoctoral Fellowship in Multivariate Statistical Machine Learning and Integrative Genomics - Ledig stilling på Aarhus Universitet Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet

🔗 Full description and application ➡️ www.au.dk/om/stillinge...

✉️ Feel free to reach out if you’d like to know more!

#PostdocJobs #StatisticalGenetics #MachineLearning #GenomicMedicine #IntegrativeOmics #SMARTBiomed #QGG #AarhusUniversity #AalborgUniversity #Genomics #ResearchJobs

Postdoctoral Fellowship in Multivariate Statistical Machine Learning and Integrative Genomics - Ledig stilling på Aarhus Universitet Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet

You will:
🔍 Develop multivariate and Bayesian models for complex trait genetics
🧬 Integrate large-scale genomic and clinical data
🧠 Apply and extend advanced multivariate modeling techniques
💻 Contribute to projects on cardiometabolic and psychiatric conditions

🚨 Postdoc Opportunity: Multivariate Statistical Machine Learning & Integrative Genomics!

We’re seeking a highly motivated Postdoctoral Fellow to join the Center for Quantitative Genetics and Genomics, Aarhus University, in close collaboration with me at Genomic Medicine, Aalborg University.

Awesome shirt 🤩

We're hiring!

Make a real difference in women's health at Hvidovre Hospital, Denmark. Use your data skills to analyze large datasets, collaborate with clinicians, and contribute to advancements in reproductive health.

Apply now: www.regionh.dk/job/s%C3%B8g...

Evaluation of Bayesian Linear Regression derived gene set test methods - BMC Genomics Background Gene set tests can pinpoint genes and biological pathways that exert small to moderate effects on complex diseases like Type 2 Diabetes (T2D). By aggregating genetic markers based on biolog...

2️⃣ BMC Genomics paper: bmcgenomics.biomedcentral.com/articles/10....

Evaluation of Bayesian Linear Regression models for gene set prioritization in complex diseases Author summary Our study introduces a new method for prioritizing biological pathways in complex diseases using Bayesian Linear Regression (BLR) models. Genome-wide association studies (GWAS) have sig...

1️⃣ PLOS Genetics paper: journals.plos.org/plosgenetics...

🔬 Both simulation studies and real data confirm increased statistical power - particularly when analyzing multiple traits together. Better tools = better understanding of disease genetics! #Genetics #Bioinformatics #Statistics

🧬 Excited to share our two recent papers in PLOS Genetics 👇and BMC Genomics 👇👇 on improving genetic pathway analysis! We've developed a Bayesian approach that outperforms current methods in identifying disease-related gene sets, especially for complex conditions like T2D.

Nice. Please also consider our two R packages for large-scale analysis of complex trait;

qgg - psoerensen.github.io/qgg/ [PMID: 31883004 & PMID: 37882742]

gact - psoerensen.github.io/gact/