Advertisement · 728 × 90

Posts by Maik Bischoff

Post image

On April 19, 1898, Camillo Golgi first described what we now call the Golgi apparatus - a structure so striking and unusual that it took more than 50 years for scientists to accept it wasn’t just an artefact.

April 19 is #GolgiDay! Celebrate the cell’s most iconic and best organelle.

3 days ago 48 11 2 2
Post image

First #Snake of the year ❤🐍

1 week ago 9 0 0 0
Post image

Visit the Marine Resources Center for a look at the marine animals used in MBL research, tour the MBLWHOI Library for a close-up of Thomas Hunt Morgan's Nobel Prize, and more.

Tours from April 20 to April 24 start at 1:00 p.m. and end at 2:15 p.m.

Sign up here: https://www.mbl.edu/events

1 week ago 7 3 1 0
Post image

EPAS1/HIF2α A530V (gain-of-function variant, oxygen-insensitive)
#VascularMalformation

👉Human N=9 (16-63 y/o)
Retinal capillary hemangioma
Ocular/Spinal venous malformation
Intracranial venous/cavernous malformation

+Evidence of Epas1 A529V🐭

@insight.jci.org 2021
insight.jci.org/articles/vie...

1 week ago 9 3 0 0
Dorsal view of a transgenic adult zebrafish. You can see the branched lymphatic system (in orange) within the brain (left) as well as scales on the body of the animal (in blue). Credit to Daniel Castranova at Weinstein Lab.

Dorsal view of a transgenic adult zebrafish. You can see the branched lymphatic system (in orange) within the brain (left) as well as scales on the body of the animal (in blue). Credit to Daniel Castranova at Weinstein Lab.

A trio of #Postdoc job openings in the #WeinsteinLab at NIH 🐟🔬

Epigenetics of development: zfin.atlassian.net/wiki/spaces/...

Vascular-associated tissues & organs: zfin.atlassian.net/wiki/spaces/...

Angiogenesis & Lymphangiogenesis: zfin.atlassian.net/wiki/spaces/...

h/t @zfinmod.bsky.social 🧪

2 weeks ago 36 22 0 0
Post image

dissecting & combating #CNS #scarring

3 weeks ago 12 3 0 0

Be there or be a square animal cap! 🧪 #DevBio

3 weeks ago 34 6 1 1
Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series
Friday, April 10, 2026, 3:00pm - 4:00 pm Eastern Time
Joaquín Navajas Acedo (Biozentrum at the University of Basel)
Spatiotemporal emergence of somatosensory neuron diversity in zebrafish
Yiqun Wang (University of California, San Diego)
Asymmetric mRNA partition mediated embryonic patterning in spiralian development revealed by spatial transcriptomics

Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series Friday, April 10, 2026, 3:00pm - 4:00 pm Eastern Time Joaquín Navajas Acedo (Biozentrum at the University of Basel) Spatiotemporal emergence of somatosensory neuron diversity in zebrafish Yiqun Wang (University of California, San Diego) Asymmetric mRNA partition mediated embryonic patterning in spiralian development revealed by spatial transcriptomics

The next the Ethel Browne Harvey Postdoc Seminar will be held Friday, April 10 at 3 pm Eastern Time with Joaquín Navajas Acedo @mads100tist.bsky.social @biozentrum.unibas.ch and Yiqun Wang @ucsandiego.bsky.social. Register today and join us. bit.ly/42xUhYh #SDBPostdocSeminar

3 weeks ago 28 12 0 4

Apply by May 1st to join an outstanding #PhD program in a cutting-edge international scientific environment and highly livable city @uni-muenster.de !
Apply at www.uni-muenster.de/CiM-IMPRS/ap...
#CiM-IMPRS @mpi-muenster.bsky.social @sfb1348.bsky.social

3 weeks ago 10 4 0 0
Advertisement
Preview
Featured image with Jan Martinek - FocalPlane Featured image with Jan Martinek - News

Happy #FluorescenceFriday! This week we are highlighting an awesome image of an Arabidopsis root from @janmartinek.bsky.social.

Check out our post to learn more about the image and about Jan’s research: focalplane.biologists.com/2026/02/13/f...
#sciart #plants #microscopy

2 months ago 23 7 0 0
Video

#FluorescenceFriday
This microscopic🔬 object is a specialized immune cell (microglia) that resides in your retina👁️ and is responsible for damage control and refinement of neural circuits. GFP labeled

@urneuroscience.bsky.social @urochestersmd.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social

3 weeks ago 47 11 1 1
Post image

✨ Somite symmetry never fails to mesmerize 🐟
Trunk somites of a 1-day-old zebrafish embryo with nuclear (💙) and membrane (🧡) labelling 📸 Image credit: Matyas Bubna-Litic (Mongera lab, UCL) 🔬 #FluorescenceFriday

3 weeks ago 34 6 1 1
microscopy images of a developing mouse spinal cord showing nuclei, actin, and membrane stains in rainbow coloring

microscopy images of a developing mouse spinal cord showing nuclei, actin, and membrane stains in rainbow coloring

Happy #FluorescenceFriday! This is a confocal 🔬 series of a developing 🐭 spinal cord showing nuclei, actin, and cellular membrane stains colored in 🌈 Microscopy by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪

3 weeks ago 48 13 1 0
Post image

#Cilia are beautiful!

That's it, that's the tweet.

Oh, and Happy #FluorescenceFriday 🔬

3 weeks ago 105 18 0 3
Preview
Featured image with Nat Prunet - FocalPlane Featured image with Nat Prunet - News

We are delighted to share this week’s featured image from Nat Prunet @nat-prunet.bsky.social, showcasing pollen grains from various plant species. Read our post to discover more about the image and learn about Nat’s research.

#FluorescenceFriday

focalplane.biologists.com/2026/03/27/f...

3 weeks ago 30 13 1 1

🌱🔬If you’re a plant biologist using imaging in your research, check back with us on Monday for an exciting announcement! @ajcellbio.bsky.social @joemckenna.bsky.social

#teaser #plantbiology #microscopy

3 weeks ago 11 4 0 0

I don't think people fully appreciate how apocalyptic things are for US science. I haven't had any new funding since 2024, but I'm still ok since typical grants are for three years. This means next year I will be completely out of funding and will have to fire everyone in the lab. It's not great.

3 weeks ago 5375 2389 43 79
Post image

There it is.

I wonder if some of its offspring next year will be tricot, too...

3 weeks ago 1 0 0 0
Advertisement
Post image

The CiM-IMPRS PhD program in #Münster is offering 16 #PhD positions in Life and Natural Sciences! Perform cutting-edge resesearch in a vibrant international setting and lively city! Apply by May 1st, 2026 - see www.uni-muenster.de/CiM-IMPRS/ap...
@uni-muenster.de
@mpi-muenster.bsky.social

1 month ago 12 12 0 1
Post image

Very pleased with our newest publication! In this study, we identify the Calcineurin-NFAT-DSCR1.4 signaling pathway as a druggable driver of capillary malformations caused by the GNAQ p.R183Q mutation, which is associated with port-wine stains and Sturge-Weber syndrome.

🔗 article: rdcu.be/e2gRC

2 months ago 18 6 3 1

So sad, I'm out of town.
For everyone in Münster: be there or be a square ◼ 😁

3 weeks ago 4 0 1 0
Post image

We are excited to welcome Stephan Huveneers (University of Amsterdam) to our @sfb1348.bsky.social seminar @uni-muenster.de. He will speak about "Force-dependent regulation of endothelial adhesion in vascular development and disease”. Everyone is welcome! More: www.uni-muenster.de/SFB1348/en/i...

4 weeks ago 8 4 0 2
Post image

🚨Attention #postdocs! Applications for our Excellence Postdoctoral Fellows Program open on April 1.

👩‍🔬Are you an early career researcher interested in working at the interface of biology & physics? We offer a 3+ year position, generous resources, and mentoring opportunities!

Apply: tud.link/y3djda

4 weeks ago 16 12 0 4
Post image

#VirtualPub We welcome Valentin Dunsing-Eichenauer, Charité Universitätsmedizin Berlin, on "Functional & deep imaging of #organoids via light-sheet #FLIM and two-photon microscopy."
🗓️ Fri, March 27 @ 13:00 CET
Register ⤵️
www.eurobioimaging.eu/events/funct...

3 weeks ago 5 3 0 1
Post image

“This recognition feels especially significant because we strive to integrate structural detail with broader cell biological understanding.” — Dr. Danielle Grotjahn (@nanigrotjahn.bsky.social). Learn more. hubs.la/Q0442hKP0

3 weeks ago 8 1 1 0
Advertisement

I had a tricot tomato this year... but the primary leaves seem to be bilateral again...

3 weeks ago 0 0 1 0
Post image

📢 BioImagingUK Community Meeting 2026 is GO!

📅 12 Oct | 10:00–17:00
📍 Natural History Museum, London
✅ Free to attend (lunch included!)

Careers, funding, community updates & more
Travel bursaries for techs & ECRs — apply by 8 May

Register👇 LINK in comments

#Bioimaging

3 weeks ago 19 8 1 1
Post image

First poster as senior author 👋

AI-based quantification of gut wall thickness in Manduca sexta using clinical CT + U-Net segmentation.

A step toward a high-throughput in vivo model bridging in vitro systems and mouse models in gut inflammation.

Great collaboration with Jan Scherberich
#EMIM #3Rs

3 weeks ago 6 1 0 0
Preview
A Sensitive Green-Red FRET Sensor for Calpain-1 Utilizing Heterodimeric Fluorescent Proteins from Distinct Evolutionary Origins Calpain-1, a calcium-dependent cysteine protease, plays a pivotal role in various biological functions. However, real-time monitoring of its activity has been limited by the lack of high-performance calpain sensors. Here, we report the development of iFoCAL, a sensitive and specific fluorescence resonance energy transfer (FRET) sensor for calpain-1, which employs mClover3 and mScarletX, a newly engineered green-red FRET pair with weak interactions. Using iFoCAL, we revealed distinct spatiotemporal patterns of calpain-1 activation: gradual and global activation in whole cells during endoplasmic reticulum (ER) calcium release, fast and focal activation in axons during mechanical stress, and region-specific activation in a Parkinson’s disease model. These findings provide the first direct evidence of distinct calpain-1 dynamics across diverse cellular contexts.

A Sensitive Green-Red FRET Sensor for Calpain-1 Utilizing Heterodimeric Fluorescent Proteins from Distinct Evolutionary Origins
pubs.acs.org/doi/full/10....

1 month ago 21 10 1 0