We’re hiring a Junior Group Leader - AI in immunotherapy - to join our team at the earliest possible date. The position is embedded within my Chair and the Chair of Cellular Immunotherapy (Michael Hudecek), and connected to CAIDAS center for AI.
med.uni-wuerzburg.de/fileadmin/03...

Workflow of single-molecule fluorescence imaging and tracking in live bacteria.

Live-cell study at the molecular level is essential for understanding the complexities of bacterial systems and protein functions in vivo. Explore recent progress on imaging probes and modalities in #MMBRJournal:

Congratulations 🥳

Very grateful to receive the Deutscher Krebspreis 2026 (Experimental Cancer Research) together with Marcus Conrad. This recognition reflects the incredible efforts of our teams and collaborators over the years
@uni-wuerzburg.de

Congratulations!

New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

RNA Splicing Lab - JOIN US Are you interested in investigating basic mechanisms in splicing regulation and gene expression? Our research group was launched in September 2024 and is hosted at the Institute of Molecular Infection...

We have an open position for a #PhD student (last week to apply!) & a lab technician/TA. For more information see: www.beuschlab.org/join-us
Interested in understanding post-transcriptional regulation and how #RNA #splicing decisions are made? Then take a look or share with people who might be! 🧪🧫

Unraveling posttranscriptional regulatory networks in phage infection Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by l…

Like bacteria, phages use sRNAs to regulate gene expression! Out today in @cp-trendsmicrobiol.bsky.social, @mvelascogomariz.bsky.social and I highlight a recent RIL-seq study from the @saharmelamed.bsky.social lab that looked into posttranscriptional regulation of lambda!

tinyurl.com/lambda-RIL-seq

Looking for a truly unique PhD programme on RNA drugs and therapeutics? We have just opened the call for the second cohort of RNAmed-Future leaders in RNA-based medicine. More details under www.rnamed.de Please spread the word.

Working at HIRI At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…

🧬 Shape the future of #RNA-based infection research!
We are inviting applications for @helmholtz.de Junior Research Group Leader Positions (f/m/d). 👉 Apply by February 15 at www.helmholtz-hiri.de/en/jobs-tale...
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The building blocks of one of the most complex flagellar nanomachines Nature Microbiology, Published online: 03 February 2026; doi:10.1038/s41564-026-02275-wA near-complete model for the complex structure of the Campylobacter jejuni flagellar motor revealed different mechanisms of assembly, activation and stability from the simple ‘classical’ flagellar model. Some of the additional motor structures in C. jejuni are conserved and only found in species of Campylobacterota, whose ancestor likely co-opted type IV pilus components from bacteria in the deep ocean.

Out Now! The building blocks of one of the most complex flagellar nanomachines #MicroSky

Uropathogenic Escherichia coli invade luminal prostate cells via FimH–PPAP receptor binding - Nature Microbiology Uropathogenic Escherichia coli infection of a murine prostate organoid model reveals a bacterial FimH–host prostatic acid phosphatase adhesin-receptor interaction enabling invasion and replication wit...

Our first paper is out today in @natmicrobiol.nature.com!

We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉

#UTI #UPEC #Organoids #AMR

🎉 Welcome to HIRI! 🎉
@cciollimattioli.bsky.social will start her new research group “Systems Microbiology of Intracellular Pathogens” at HIRI in February. Together with her team, she will investigate the molecular mechanisms that shape interactions between intracellular pathogens & their host cells.

Let’s get this started and on an RNA high 😅

Ein einzelnes Blutplättchen bildet entzündungsfördernde PITTs in einem entzündeten Blutgefäß. - Copyright Lehrstuhl für Experimentelle Biomedizin I, Universitätsklinikum Würzburg

Würzburger Forscher entdecken neuartige Entzündungsfunktion von Blutplättchen
Ein Team der Würzburger Universitätsmedizin hat das Verständnis der Thrombozytenbiologie grundlegend geändert. Es zeigt in Science, dass das Oberflächenprotein...
weiterlesen

Wir haben eine Promotionsstelle im Bereich Infektionsbiologie/Parasitologie zu besetzen!

Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT Abstract. Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular surv

RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...

Grateful to be among the 25 inspiring women featured in @zeit.de as part of the #Zia fellowship for Visible Women in Science. Thanks to @uni-wuerzburg.de for their support and to everyone involved for making scientific work by women more visible. Honored and proud to be part of this initiative ☺️.

Bacterial population structure and clade-specific sampling affect machine learning predictions of antimicrobial resistance (AMR). Top: An illustration of defining clades for genomes in one species. R: resistant (triangles), S: susceptible (circles). Bottom left: An example of training scenarios for scheme B based on the clade splitting in shown above. Models were trained on all samples except for resistant or susceptible samples from one clade. The held-out genomes from the same clade were used as the test sets. Bottom right: The precision and recall scores for scheme B; a-random and b-random indicate testing on random train-test splits of the pathological unbalanced data.

#MachineLearning methods are used to predict #AntimicrobialResistance #AMR from genomic data. @lbarquist.bsky.social &co show that sampling biases driven by population structure severely undermine the accuracy of AMR prediction models even with large datasets @plosbiology.org 🧪 plos.io/4iZ0zXQ

Nature’s 10: Ten people who shaped science in 2025 A fired public-health official, a mosquito breeder and a baby with a smile seen around the world. These are just a few of the remarkable people chosen for Nature’s 10.

A fired public-health official, a mosquito breeder and a baby with a smile seen around the world. These are just a few of the remarkable people chosen for Nature’s 10 2025

go.nature.com/4q9upvr

© Bayerische Staatskanzlei

Today, Minister-President Markus Söder awarded @jorg-vogel-lab.bsky.social the Bavarian Maximilian Order. Presented every two years, the award recognizes outstanding accomplishments in science & the arts and is regarded as one of the state’s highest honors. Congrats on the “Bavarian Nobel Prize”! 👏🎉

Structures of the bacterial flagellum of Salmonella enterica

#MicrobiologyMonday: The bacterial flagellum is built through a hierarchical assembly process and powered by a dynamic motor capable of astonishing speeds. What's new in our understanding of these complex nanomachines? Find out in #MMBRJournal: asm.social/2HB

Open-Source Developer for Deep Learning Antibiotic Discovery Platform - Research Introduction Antimicrobial resistance (AMR) is one of the most urgent global health threats projected to cause up to 10 million deaths per year by 2050. The AI4AMR project brings together teams from I...

If you're interested in developing an open-source image analysis platform/plugin to profile bacteria with deep learning while living in the beautiful city of Paris 🇫🇷, check out this job ad from the @chzimmer.bsky.social lab @pasteur.fr

research.pasteur.fr/fr/job/open-...

Check this out! A napari plugin for AI-based analysis of microbial bioimages! 🔬🦠💻

🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training

📜 www.biorxiv.org/content/10.1...

What an incredible weekend at the kickoff meeting of the @zeit.de #Zia programme for #VisibleWomenInScience. Deeply grateful to the organisers and the many inspirational women, who shared their stories and energy. Looking forward to the fellowship year ahead with this exceptional group of women!!!

JB Editor's Choice: Waller, Ribardo & Hendrixson show that flagellar length impacts function, with short flagella slowing swimming and reducing host colonization, indicating the important of regulating the lenght of the filament.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

Von links nach rechts: Markus Blume, Patrick Cramer, Markus Söder, Simone Schwanitz und Hubert Aiwanger

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Die Bayerische Staatsregierung und die @maxplanck.de wollen den Wissenschaftsstandort Würzburg stärken. Ein heute unterzeichnetes Memorandum of Understanding legt den Grundstein für den Ausbau der Forschung in der Biomedizin. Auf eine starke Partnerschaft!
📸 Axel Griesch

Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!

For more information and how to apply, see below 👇

Please RT!

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)