Let’s talk CRISPR, cancer, and innovation! #cshlcrispr25 #CRISPR #p53 #cancerresearch #metastasis #CancerGenomics
@cshlmeetings.bsky.social @cshlnews.bsky.social @cshlaboratory.bsky.social @columbiacancer.bsky.social @columbiamed.bsky.social

From high-throughput in vivo CRISPR knockout screens to precision base & prime editing, this project dissects tumor evolution at an unprecedented resolution. Our findings underscore the emerging potential of allele-specific treatments in precision oncology.

We're combining cutting-edge in vivo CRISPR strategies with cancer research to uncover how mutant p53 drives metastasis—mutation by mutation.

🚨Thrilled to announce I have presented our work at the Cold Spring Harbor Genome Engineering: CRISPR Frontiers Meeting (
@cshlaboratory.bsky.social
) Aug 12–16! 🧬✨

LATE BREAKING RESEARCH-
"Decoding tumor cell dynamics driven by mutant TP53 gain-of-function activity in squamous cell carcinoma metastasis"
April 27, 2025, 4:05 PM - 4:20 PM CST/5:05 PM- 5:20 PM
Presenter:
@gizemefephd.bsky.social , PhD