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Posts by Lan Mapa

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Algal Swimming Patterns Change with Light Intensity In response to changes in illumination, a swimming microorganism reverses the direction of its circular trajectory by tilting its flagella’s planes of motion.

Some algae swim in circles, by exercising exquisite control of their breaststroke. And they switch direction under light of different intensity. Here's how. (No one is yet quite sure why.)
physics.aps.org/articles/v19...

2 months ago 41 7 1 1
Smart microscopy for automation of optogenetic targeting
Smart microscopy for automation of optogenetic targeting In this Virtual Pub recording, Lucien Hinderling of the University of Bern gives a talk on "Smart microscopy for automation of optogenetic targeting." Learn more about the Virtual Pub:…

🎥 Don't miss this recording of the #VirtualPub with @lhinderling.bsky.social PertzLab on Smart Microscopy workflows - for automation of optogenetic targeting & beyond.
Great talk 👏 🔽
youtu.be/YpGmMzrFJ80

2 months ago 13 5 0 1
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FACED 2.0 enables large-scale voltage and calcium imaging in vivo - Nature Methods FACED 2.0 builds on and expands the capabilities of the free-space angular-chirp-enhanced delay microscopy approach. Its high speed, large field of view and volumetric coverage enable two-photon volta...

FACED 2.0: a method for high-speed, large FOV, volumetric 2-photon voltage and calcium imaging in the mouse and zebrafish brain.

www.nature.com/articles/s41...

4 months ago 7 1 0 0

Hi, I used this site for mounted diatom samples. Really nice for demonstrating other types of transmitted light contrast enhancing techniques. I'm not sure if they ship outside EU, though. www.diatomshop.com

4 months ago 2 0 1 0
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Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

6 months ago 62 80 2 8
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Fibronectin, a key component of the vessel wall, triggers smooth muscle cells to release collagen-rich extracellular vesicles that guide their movement during vessel repair and atherosclerosis.
buff.ly/YOkDI4a

6 months ago 24 5 0 1

#GEF25 the expansion microscopy community would benefit from high NA, long working distance water objectives. Who's working on these? What's out there?

6 months ago 43 13 13 1
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New Molecules and Indications for GLP-1 Medicines This Perspective explores recent progress and future directions in glucagon-like peptide-1 medicines.

2 decades after the first GLP-1 drug, we're still in the early stages for where this is headed. Nice, succinct summary and graphic by a pioneer of the field: @danieljdrucker.bsky.social
jamanetwork.com/journals/jam...

7 months ago 142 26 3 1
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Computational image analyst (m/f/d) The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

7 months ago 87 86 1 1

Today I learned that one possible endpoint of the carcinization process is a high-tech optical component

anything -> crab -> crab powder -> diffraction grating -> laser

stands to reason

7 months ago 50 10 1 1
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Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.

7 months ago 27 10 1 1
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Roundup: Unobligated but Not Unnoticed: OMB Pulls Back NOAA Funds August 12-26, 2025

A disaster for ocean and climate research is unfolding before our eyes. #NOAA 🌊
"The White House Office of Management and Budget is pulling back $239 million in funds Congress already provided. The biggest hits fall on climate and ocean research."
oceanpolicy.substack.com/p/roundup-un...

7 months ago 33 20 1 1

Refractive index mapping below the diffraction limit via single molecule localization microscopy www.biorxiv.org/content/10.1101/2025.08....

7 months ago 1 1 0 0

Single-molecule flow cytometry www.biorxiv.org/content/10.1101/2025.08....

7 months ago 9 4 0 0
A copy of Janelle’s book - the UK paperback in fact - signed in green and doodled with a little robot box. A few other books are in the background.

A copy of Janelle’s book - the UK paperback in fact - signed in green and doodled with a little robot box. A few other books are in the background.

The terminal B Tattered Cover at Denver Airport has six signed copies of You Look Like a Thing and I Love You!

8 months ago 28 1 0 0
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blog.addgene.org OCaMP: A New Calcium Indicator for Neural Imaging

Looking for a calcium sensor to fill the gap between red and green spectra? Orange you glad we asked! Check out our latest blog post on OCaMP, by @abhiaggarwal.bsky.social!

8 months ago 7 2 0 0
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Why hearing in noisy places gets harder with age, even with “normal” hearing

This study links hidden damage in the ear's neural wiring to speech-in-noise difficulties and increased listening effort in middle-aged adults.
buff.ly/m9fS8Nv

8 months ago 8 4 0 0
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Can creativity in science be learnt? These researchers think so Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science.

Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science

go.nature.com/459cPQz

8 months ago 49 10 0 2
artwork depicting an ancient bird, that looks like a blue jay, with an iridescent feathered crest on its head

artwork depicting an ancient bird, that looks like a blue jay, with an iridescent feathered crest on its head

A 125-million-year-old fossil feather may have shimmered with iridescent colour, possibly for courtship.

The study presents ‘fundamental’ findings, but reviewers note the evidence isn’t yet conclusive. Read the reviews and author responses: buff.ly/hwQ2P1D
#EvoBio

8 months ago 10 3 0 0
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1/N What are the organizational principles underlying crossmodal cortical connections?
We address this in this new preprint, led by @alexegeaweiss.bsky.social & ‪@bturner-bridger.bsky.social‬ in collab w/ ‪@petrznam.bsky.social‬ @crick.ac.uk
www.biorxiv.org/content/10.1...

8 months ago 91 33 1 5

Voltage Imaging with Periodic Structured Illumination www.biorxiv.org/content/10.1101/2025.07....

8 months ago 2 1 0 1

The “what if we inject it full of fluorescent laser dye and energize it with another laser” approach to the “will it lase” challenge.

The answer for peacock feather appears to be “yes, and noticeably better than other animals we’ve tried”

8 months ago 161 22 3 2
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Differentiation and identification of commensal and pathogenic oral bacteria at strain level using ATR-FTIR spectroscopy The correct identification of different bacteria is a critical task in clinical applications and basic research especially in the oral cavity which has a complex bacterial community. Complementary to ...

Sharing our recent work on using old-school FTIR spectroscopy for species classification of oral bacteria!

pubs.rsc.org/en/content/a...

8 months ago 1 0 1 0
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The oceans are overheating—and scientists say a climate tipping point may be here In 2023, the world’s oceans experienced the most intense and widespread marine heatwaves ever recorded, with some events persisting for over 500 days and covering nearly the entire globe. These searin...

🌊 The oceans are overheating - and scientists say a climate tipping point may be here

www.sciencedaily.com/releases/202...

8 months ago 78 38 5 2
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Giant study finds a research field that’s mostly reproducible Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.

We're all too used to seeing news of a "reproducibility crisis" in science.

So it is interesting to find that a huge project that reviewed a whole field - Drosophila fruit fly immunity - over 50 years has found that at least 61% of claims in it are verifiable. 🧪🧵1/10
www.nature.com/articles/d41...

9 months ago 37 13 4 1
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How to spot dementia early and reduce your risk by half | BBC Science Focus Magazine New science is uncovering how Alzheimer’s could be detected decades before symptoms strike.

Could we one day detect Alzheimer's before symptoms emerge?

Anthea Rowan for BBC Science Focus dives into a new study that finds the Alzheimer's disease has two distinct phases - an early 'stealth' phase and a devastating later phase.

🧠📈 www.sciencefocus.com/the-human-bo...

10 months ago 15 7 1 1
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Using new adaptive-optics techniques, researchers have created ultra-high resolution images of the Sun's corona--and the results are astonishing.

This video shows "coronal rain": loops of magnetic plasma arching out from the Sun, cooling, and flowing back down. 🧪🔭

nso.edu/press-releas...

10 months ago 332 76 11 16
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📢 WE ARE HIRING!

We're looking for a postdoctoral researcher to study how to apply optical techniques💡 to recover the information of historical wall paintings for the preservation of the UNESCO World Heritage Site La Pedrera-Casa Milà. 🖼️

Apply now 👉 jobs.icfo.eu/?detail=972

@icfo.eu

1 year ago 4 3 0 0

Only a few days left to apply. 2yr fully funded postdoctoral position at the interface between microscopy, nanoscience, Raman spectroscopy, microfluidics, single-cell analysis, and microbiology.

1 year ago 5 7 0 0
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Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!

1 year ago 49 28 2 2