Why are #sulfur containing planar chiral [2.2]paracyclophanes attracting so much attention?🧪This new review by Stéphane Perrio & co-workers explores synthetic strategies and applications from #catalysis to materials science✨
👉 buff.ly/NBZp4Xv
Posts by Synthesis Journal
Discover in the latest work by Takuji Kawamoto and co-workers how allyl bromides enable efficient radical #allylation of vinyl perfluorocyclic #sulfonamides, opening new routes to allylated fluoroalkyl sulfonamides✨
👉 buff.ly/GjLLu2L
Explore the frontier of enantioselective #hydroarylation with Yamakawa & Nishimura ✨ This review breaks down how transition-metal catalysts are unlocking complex chiral molecules from disubstituted alkenes—an atom-economical leap for modern synthesis🎯
#catalysis
👉 buff.ly/kY9cFNg
Lecture of Prof H. Ohmiya @hirohisaohmiya.bsky.social on "Boron-Enabled Radical Chemistry" now starting online ( @synthesis1969.bsky.social Cheminar), introduced by Prof. Martin Oestreich @silicon-martin.bsky.social .
Uncover the power of Nitroarene Photocatalysis with Daniele Leonori & co-workers✨ This study reveals how #nitroarenes act as energy-transfer catalysts to transform cinnamyl chlorides into #cyclopropanes, eliminating the need for transition metals.
#photocatalysis
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Dive into the latest on Ni-catalyzed alkene–imine couplings by Li-Jun Xiao &co-workers! From nickelacycle intermediates to green chemistry🌿and photoredox techniques, discover how this research is expanding the synthetic toolbox for medicinal and materials chemistry✨
#nickel
👉 buff.ly/NALTRMu
Frederic Patureau & co-workers explore α-trifluoromethyl #styrenes as powerful platforms for defluorinative radical & nucleophilic functionalization🧪While indoles favor (Z)-fluoroalkenes, phenothiazines unexpectedly switch the outcome to (E)-configured diphenothiazinated products!
👉 buff.ly/BOkty6I
Yadagiri & co-workers explore how #carbenes from diazo compounds unlock cyclopropenation, C–H insertion, annulation & cycloadditions under visible light🌈 Forging C=C, C–C & C–heteroatom bonds in a single step — often without a photocatalyst, opening new doors to #heterocycles
👉 buff.ly/BOkty6I
Step into the chemistry of imido-substituted quinones✨ Shinji Tanimori & co-workers report the formation of 2-bromo-1,4- #naphthoquinones and #benzoquinones under mild conditions using NBS & DABCO — with evidence of a partially radical pathway⚡
👉 buff.ly/SsiBEgr
Join Thieme #Cheminar “Boron as a linchpin in catalysis”🧷 featuring Profs. Hirohisa Ohmiya @hirohisaohmiya.bsky.social 🇯🇵, Elena Fernández 🇪🇸, James Morken 🇺🇸 & chaired by our EiC Prof. Martin Oestreich @silicon-martin.bsky.social 🇩🇪
📅 April 14, 2026
⏰ 4 PM (CEST)
Sign up today 👉 buff.ly/k73c6Xj
Griseoviridin & viridogrisein💊 These synergistic type A/B #streptogramins cooperatively block protein translation in Gram-positive pathogens🦠 This review by Xu & Renata highlights their #bioactivity & key biosynthetic/synthetic advances driving next-gen analogs against resistance🔬
👉 buff.ly/IB2ZSHN
Ethyl 3-ethoxy-3-iminopropanoate hydrochloride (EEIP·HCl) is emerging as a powerhouse precursor for nitrogen-rich heterocycles, streamlining cyclizations toward high-density, stable, high-performance HEDMs🚀 Kukreja & Dharavath spotlight its growing impact✨
#triazoles
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Dive into the chemistry of #cotylenin & #fusicoccin ✨ Discover how they modulate 14-3-3 protein–client interactions and check out the divergent syntheses of brassicicene & talarmalnoid B using Studer’s Mukaiyama hydration by Shenvi @shenvi.bsky.social & co-workers
#TotalSynthesis
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Discover the fascinating world of helical #homochirality in nature, biology, and synthetic systems🌀 This new publication by Percec & co-workers highlights key examples, their mechanisms, historical milestones, and links across molecular to macroscopic systems🔬
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Join Thieme #Cheminar “Thieme Chemistry Journals Awardees 2026”🔬 featuring Drs. Yagnaseni Roy, Javier Mateos, Clément Ghiazza @clementghiazza.bsky.social, Elisabeth Kreidt @ekreidt.bsky.social & Prof. Charles Loh
📅March 30, 2026
⏰4 PM (CEST)
Register 👉 buff.ly/GLQwo3T
A novel silane-driven reductive #deoxygenation of ketones by Makoto Onaka & co-workers delivers either olefins or methylenes with high selectivity⚗️ Using H-montmorillonite, the method even gives direct 1,2-dibromides — no olefin isolation needed 🔬🚀
👉 buff.ly/nkHwz7Y
Following their widely cited #NewTools article, Thomas S. Teets’s group has launched a searchable database for #photosensitizers buff.ly/VCPsybf
Filter by photophysical & redox properties to quickly find the right catalyst⚡
Read here👉 buff.ly/HFSN9LS
Updates and new entries welcome: tteets@uh.edu
Catalytic #hydroamidation of alkenes & alkynes with #dioxazolones is emerging as a powerful route to diverse amides⚗️ In their review, Liu, Liu, Wang and Liu highlight advances with metal catalysts, mechanistic insights & future opportunities🚀
👉 buff.ly/Matkbdy
Advancing access to bioactive #aminoacids 🧬 Radovan Šebesta & co-workers report a reliable, multi-step synthesis of (S)-quisqualic acid from L-serine with solid yields—complete with full characterization for reproducible use in medicinal research🧪
👉 buff.ly/hl85ji0
Dive into the chemistry of #cyclopropanes🔺 From classic Simmons–Smith to tunable, highly reactive Shi #carbenoids, Feng & Du unlocked powerful tools for cyclopropanation, even asymmetric versions of unfunctionalized olefins!
👉 buff.ly/bPLdGpw
Thieme Cheminar April 14th: Boron as a linchpin in catalysis ( @synthesis1969.bsky.social ; @synlettjournal.bsky.social ):
#Boron @boron-chemistry.bsky.social. H. Ohmiya; M. Oestreich ( @silicon-martin.bsky.social ); M. E. Fernández Gutiérrez; J. Morken. Registration: cassyni.com/events/RtDpJ...
✨A first-in-class approach to 2-substituted #indoliums! Using only a #silver catalyst and silica gel, Shuji Yasuike and co-workers report a mild, efficient synthesis—plus insights into Ag–SiO₂ interactions and future fluorescent cationic heterocycles 🚀🧪
👉 buff.ly/Efg05Fr
Dearomatization made versatile✨ Juntao Ye & co-workers unveil a photocatalytic hydroboration strategy delivering 3D boron heterocycles—with broad scope and room to expand to other heteroarenes🧠
#photocatalysis #boron
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Toward a toolbox of organic reductants⚗️ Mario P. Wiesenfeldt & co-workers @wiesenfeldtlab.bsky.social show how metal-free strategies enable predictable C–C bond reductions in complex, drug-like molecules💊
#organocatalysis
Read more 👉 buff.ly/OsDpegR
Discover a faster, solvent-free route to Boscalid⚗️ Hajime Ito @hajito1.bsky.social & co-workers report a rapid, scalable mechanochemical synthesis that cuts time, waste, and energy!
#mechanochemistry #SuzukiMiyaura
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Synthetic electrochemistry goes interfacial⚡This review by Jianchun Wang & co-workers explores how chemically modified electrodes—nanoparticle-based or catalyst-immobilized—unlock new reactivity, selectivity, and mechanistic insight in organic #electrosynthesis
Read more 👉 buff.ly/Lr2DimW
Azo-peptide synthesis by Oestreich @silicon-martin.bsky.social & co-workers — no stereochemical compromise✨Pd-catalyzed C(sp²)–N(sp²) cross-coupling enables epimerization-free installation of #azobenzene units onto amino acids and small #peptides
Read more 👉 buff.ly/DpAcyVM
Rearranging with precision🔄 Eiji Tayama & co-workers uncover how ring strain steers Sommelet–Hauser over Stevens #rearrangement, delivering enantio- and diastereopure α-arylamino acid amides via chirality transfer🧪
#ammonium
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Yu Zhao & Jun Xuan review how visible-light #photochemistry drives S–N bond cleavage to difunctionalize alkenes & alkynes, unlocking efficient routes to bioactive sulfur–nitrogen motifs💡
#radicals
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✨Special Topic Dedicated to Prof. Knochel✨
A powerful photochemical coupling of aryl #azides & anilines delivers hard-to-access N-aryl-ortho-phenylenediamines via singlet #nitrene chemistry enabled by a Lewis acid💡Great work by Ruffoni & Leonori
#OpenAccess for a limited time 👉 buff.ly/yiR3P6O