Ethyl 3-ethoxy-3-iminopropanoate hydrochloride (EEIP·HCl) is emerging as a powerhouse precursor for nitrogen-rich heterocycles, streamlining cyclizations toward high-density, stable, high-performance HEDMs🚀 Kukreja & Dharavath spotlight its growing impact✨
#triazoles

👉 buff.ly/tQ1cYeP

#Medsky🧪 #IDsky #microsky #pharmsky #publichealth Mortality from invasive aspergillosis remains unacceptably high & the currently recommended treatment of #triazoles is further challenged by rising resistance to these first-line agents.
Mortality from invasive aspergillosis remains high,

Grey partridge. Photo: Frank Vassen , Wikimedia Commons

Cropped part of Fig. 1 from the article: Ways of exposure of birds and eggs and the proposed adverse outcome pathway based on triazoles effects on bird reproduction.

Award issue: @jjimenezpenuela.bsky.social and colleagues review the adverse effects of triazole fungicides on reproduction and physiology of farmland birds.

➡️ vist.ly/4qen2

#ornithology #triazoles #farmland #fungizides #birds #reproduction

✨From Special Topic Romanian Chemists in Synthesis✨

One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles

👉 buff.ly/CqvtWHP

Phenylpyridine-Based Boron Azides: Tuning Reactivity and Accessing Fluorescent Triazoles | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Škoch and co-workers @inorg #boron #azides #triazoles

Uncover the selectivity!✨ Zanatta & co-workers are presenting a direct N-alkylation/arylation methodology for #imidazoles, #pyrazoles, and #triazoles. Their work, featuring brominated enones, creates N-alkylated #azoles with furans or dihydrofurans.

👉 buff.ly/wzbCzlm