In this full research paper, the synthesis of N-doped chiral #macrocycles by regioselective palladium-catalyzed #arylation is described.
➡️ https://tinyurl.com/kwu6uvmp
#dihydroindolocarbazole #InherentChirality #nonplanarity 
#BJOC #DiamondOpenAccess 💎🔓

Pentagonal Bipyramidal First-Row Transition Metal Complexes with Macrocyclic Ligand Containing Two Pyridine-N-Oxide Pendant Arms: Structural, Magnetic, and Theoretical Studies | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Drahoš and co-workers @InorgChem #first_row #py_N_oxide #macrocycles #SMM

Researchers at the University of Duisburg-Essen @unidue.bsky.social developed novel approaches towards the synthesis of #CrownEthers that contain one or two #BINOL units. 👉 https://tinyurl.com/3fhbvd9m
#chirality #macrocycles #SupramolecularChemistry #Organocatalysis
#BJOC 💎🔓
@riebe-chem.bsky.social

Dihydropyrazine-embedded macrocycles behave like supersized cycloalkanes Giant molecular rings that mimic the puckered shapes of cyclobutane, cyclopentane and cyclohexane could offer new insights into conformational dynamics

Dihydropyrazine-embedded macrocycles behave like supersized cycloalkanes #Science #Chemistry #OrganicChemistry #Dihydropyrazine #Macrocycles #Cycloalkanes

✨From Special Topic Romanian Chemists in Synthesis✨

One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles

👉 buff.ly/CqvtWHP

What is the significance of the evolution from chiral molecular macrocycles to chiral topological macrocycles? A novel strategy was designed for guiding supramolecular macrocycles into nanoscale chiral topological toroids, establishing hierarchical self-assembly pathways for advanced chiroptical materials

26-Sep-2025
What is the significance of the evolution from #chiral molecular #macrocycles to chiral topological macrocycles?

https://www.eurekalert.org/news-releases/1099922

#science #chemistry #selfAssembly #nanoworld #macromolecules '#supramolecularChemistry #chirality

Kyle Plunkett and co-researchers from the Southern Illinois University and the University of Illinois Urbana-Champaign explore the binding of hypervalent iodine #macrocycles with two first group #AlkaliMetals.
🔗 https://tinyurl.com/jhj9w2up
#HypervalentIodine #SupramolecularChemistry #BJOC 💎🔓

Polyfluorinated reagents for peptide stapling Peptide stapling has emerged as a valuable approach for modulating peptide structures and enhancing their functional properties, with broad applications for drug discovery and biomolecular engineering...

🔥Check out latest review in OCF discussing how to make peptide #macrocycles using fluorinated reagents

👉Polyfluorinated reagents for peptide stapling

doi.org/10.1039/D5QO...

🧪 The RSC Organic Division Ireland meetings yesterday featured #macrocycles, #fluorescence, improving efficiency in chemistry and moving towards #sustainable chemical synthesis, combining optimism, innovation and an acknowledgement of the significant challenges faced.

#Chemsky #SciComm

Expanding the Family of Monosubstituted 15-Membered Pyridine-Based Macrocyclic Ligands for Mn(II) Complexation in the Context of MRI | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Tóth, Drahoš, and co-workers @InorgChem #manganese #15pyN3O2 #macrocycles #MRI

Very nice work on functional #macrocycles presented by Bernd M. Schmidt @bmschmidtlab.bsky.social at the #Chemiedozententagung #CDT2025.

Embark on a journey through this captivating account by Sambasivarao Kotha and co-workers on strategies combining metathesis with various reactions to generate molecular diversity in #carbocycles, #macrocycles, and #heterocycles.
👉 thieme-connect.com/products/ejo...

A giant mechanical bull seen from the side as it faces to the right. It's 10 metres tall and called Ozzy. It lives in Birmingham New Street station.

My journey to #MASC2024 starts in ebullient mood despite the early hour.

Looking forward to the next 2 days of #macrocycles and #supramolecular #chemistry in York!

#Chemsky

Unveiling the Potential of Sulfur-Rich Macrocyclic Chelators Against Cadmium Poisoning | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Tosato and co-workers @InorgChem #cadmium #poisoning #sulfur_rich #macrocycles #chelators #coordination_chemistry #DO4S

#Vilya is on BlueSky! Follow us for updates on our journey to transform the way #medicines are discovered and developed!

#DrugDiscovery #Macrocycles

📢 Invitation to submit!

New thematic issue “Novel #macrocycles: from synthesis to #supramolecular function” edited by Prof. Pablo Ballester, Konrad Tiefenbacher, Carmine Gaeta, Carmen Talotta, Margherita De Rosa and Paolo Della Sala in the Beilstein Journal […]

[Original post on hessen.social]

Doctoral Student in Computational Chemistry

Fully funded #PhD opportunity: structure-#permeability relationship of #macrocycles at ETH (Zurich Switzerland) start: early 2025 | closing 31-Aug-2024 #CompChem #cheminformatics #ChemPhD #chemsky 🧪
jobs.ethz.ch/job/view/JOP...

Orange red sunrise behind the almost silhouetted clock tower at the University of Birmingham. The roof of the Chemistry building is in the foreground, covered in pipes.

Good morning #MASC2023!
Welcome to @unibirmingham all the MASC 2023 delegates, it's almost time for the conference to start 😀
Looking forward to an excellent couple of days of #macrocycles and #supramolecular #chemistry!
#ChemSky 🧪