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Toward a toolbox of organic reductants⚗️ Mario P. Wiesenfeldt & co-workers @wiesenfeldtlab.bsky.social show how metal-free strategies enable predictable C–C bond reductions in complex, drug-like molecules💊
#organocatalysis

Read more 👉 buff.ly/OsDpegR

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Cracking a century-old puzzle🔍 Andrew Smith & co-workers explore [1,2]-rearrangements of #ammonium ylides—tackling selectivity, probing radical pathways, and redefining how these elusive allylic shifts may occur✨
#organocatalysis #radicals

👉 buff.ly/LOT16BC

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It was a great pleasure to host Prof. Christoph Schneider (Universität Leipzig) for a #GDCh lecture at @fau.de! Christoph presented his recent work on a novel #umpolung strategy for #enantioselective synthesis!
@gdch.de @ekatl.bsky.social @dubelab.bsky.social #Organocatalysis #AsymmetricCatalysis

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Asymmetric synthesis of 2-arylethylamines, key motifs in bioactive compounds and #MedicinalChemistry.

This graphical review highlights 2025 advances in metal-free and metal-catalyzed methods, including #Organocatalysis, #Photocatalysis and #Biocatalysis. 🧪

🔗 Read here: bit.ly/3LORTHq
#ChemSky

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✨Special Topic Dedicated to Prof. Knochel ✨

Radical chemistry for remote C–C & C–heteroatom bond formation🔬 This review by Dagousset et al. highlights decades of advances in functionalizing α,β-unsaturated carbonyls🌟
#photocatalysis #organocatalysis

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7

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The poster pitches at #NWOCHAINS were an absolute firework of great #science on #antivirals, #organocatalysis, #MolecularMotors, #EnzymeEngineering, #photocontrol, #odor, #bacteria, #recycling, #batteries, #QuantumDots, #vitrimers, #BoneRegeneration, native #MassSpectrometry and #biomaterials.

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H₂-driven CuH catalysis with multifunctional NHCs⚡Guanidine- & iminopyridine NHCs expand reactivity to challenging amides & conjugated substrates🔬Unprecedented substrate scope & a step toward 3d-metal hydrogenations by Teichert et al. @teichertlab.bsky.social
#organocatalysis

👉 buff.ly/3K4tj1A

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Peter Schreiner, Nov. 1021 · photo by Ralf Hahn

Peter Schreiner, Nov. 1021 · photo by Ralf Hahn

🎁Happy 60th birthday, Peter Schreiner! With the spectacular synthesis of “impossible” #hexanitrogen (doi.org/10.1038/s415...) he basically gave himself the perfect present. #OrganicChemistry #MatrixIsolation #Organocatalysis #ComputationalChemistry

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Researchers at the University of Duisburg-Essen @unidue.bsky.social developed novel approaches towards the synthesis of #CrownEthers that contain one or two #BINOL units. 👉 https://tinyurl.com/3fhbvd9m
#chirality #macrocycles #SupramolecularChemistry #Organocatalysis
#BJOC 💎🔓
@riebe-chem.bsky.social

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Ethyl but-3-ynoate as a versatile C2 building block🧩 Enables asymmetric (4+2)-heterocycloadditions with Michael acceptors⚡ Chiral isochalcogenoureas deliver highly functionalized #dihydropyrans with excellent selectivity in the study by Waser & co-workers✨
#organocatalysis

👉 buff.ly/NlVUSKk

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In this work by Joyce Grimm & Nobel Laureate Benjamin List, the intramolecular #Prins reaction of O-prenylated #salicylaldehydes delivers 4-chromanols with outstanding efficiency & selectivity using a fluorinated iIDP #Brønsted acid catalyst⚗️
#organocatalysis

👉 buff.ly/ttXDIM9

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🌟From Cluster Hydrogen Atom Transfer Reactions🌟

Kokotos & co-workers present a green, metal-free approach🌱 for selective C–H activation: #hydroacylation of alkenes using NBI #photocatalysis under blue LEDs💡
#organocatalysis

Read more👉 buff.ly/c5NKx3e

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New @chemrxiv.org: interested in an inexpensive way to take advantage of carbenoid reactivity without excluding humidity or oxygen? Take a look here: doi.org/10.26434/che... #nhc #organocatalysis #polymerization #chemsky

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Jun-Long Li & team unveil a para-selective acylation strategy for ultra-remote aryl C(sp²)–H bonds using radical #NHC #organocatalysis. Huge potential for pharmaceuticals, amino acids, and peptides!
#catalysis

👉 buff.ly/XEYDgeR

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The future of chemistry isn't about pure compounds–it's about understanding complex mixtures. De, Pramanik & Schmittel's new research, inspired by biological networks, explores molecular communication protocols in artificial systems
#organocatalysis

👉 buff.ly/eTbmqZn

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Preview
Recent progress in selective functionalization of diols via organocatalysis Polyols bearing multiple hydroxyl groups present persistent challenges for site-selective functionalization due to their inherent reactivity similarity. As minimal polyol systems, diols offer a practi...

🔓 #OpenAccess #diols #organocatalysis

👉 This review highlights recent progress in organocatalyzed diol functionalization, with a survey of organocatalysts incorporating boron, nitrogen, and phosphorus-based motifs, as well as emerging #photoredox methodologies.

doi.org/10.1039/D5QO00645G

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While rest of us had group meeting in the rain🌧️ @tbsi-tcd.bsky.social @tcddublin.bsky.social in Dublin: Karolina, Sophie, and Liam are off into the sun 🌞in Salerno at the #SupraChemDays25 meeting showing off cool chemistry ⚗️on #porphyrins, #organocatalysis, #atropisomers, #bicyclopentane 😀

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Desymmetric esterification catalysed by bifunctional chiral N-heterocyclic carbenes provides access to inherently chiral calix[4]arenes - Nature Communications Calix[4]arenes display inherent chirality, with broad applications in synthetic and medicinal chemistry and in materials sciences, but their use is hindered by their limited synthetic accessibility. H...

Dr. Vojtěch Dočekal and Prof. Jan Veselý developed an efficient method to synthesize inherently chiral calix[4]arenes using #organocatalysis ⚗️—no need for racemate separation.
Potential applications include #catalysis and molecular recognition 🔬

📄 Read more: www.nature.com/articles/s41...

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Our Nika Melnyk presented her PhD journey at the Dublin Chemistry 3rd Year Talks 2025 and absolutely nailed it! 💥

“Catalysis of Organic Reactions Through XB-Based Organocatalysis.”

Super proud of her!
@tcddublin.bsky.social @manchester.ac.uk
#CompChem #Organocatalysis
#ProudSupervisor

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The thematic issue “Advances in asymmetric #organocatalysis II” ed. by Radovan Šebesta @rsebesta.bsky.social, @comeniusuni.bsky.social, in the Beilstein Journal of Organic Chemistry is complete ➡️ https://tinyurl.com/yc24a85y
#GreenChemistry #greensolvents #catalysis #DiamondOpenAccess 💎🔓 #BJOC

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In this full research paper, the first example of the organocatalyzed kinetic resolution of 1,5-dicarbonyl compounds prepared by a Michael addition reaction is described: 

➡️ www.beilstein-journals.org/bjoc/articles/21/34

#KineticResolution #organocatalysis #BJOC 💎🔓

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Save the date 📅 Dec. 10, 2024 🕒 3–4 pm CET
Online #BeilsteinTalk “Computationally-led catalyst design" with Cristina Trujillo, The University of Manchester.
As #organocatalysis remains one of the most challenging topics in contemporary organic chemistry, Dr […]

[Original post on hessen.social]

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Let's give this app a go! Follow for news from our lab @newcastleuni.bsky.social focusing on #fluorine, #photochemistry and #organocatalysis!

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There’s still time to submit to the thematic issue “Advances in asymmetric #organocatalysis II” edited by Radovan Sebesta, Comenius University Bratislava, in the Beilstein Journal of Organic Chemistry:
➡️ […]

[Original post on hessen.social]

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