Activating the hidden pharmaceutical potential of bacteria | German Center for Infection Research Microorganisms produce a wide variety of natural products that can be used as active agents to treat diseases such as infections or cancer.

Cold bacteria hold the key to new #antibiotics?

Researchers at Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and @dzif.bsky.social have developed #ACTIMOT, a method to exploit bacterial genetic blueprints for producing natural products.

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Exciting! Researchers at HIPS developed 𝗔𝗖𝗧𝗜𝗠𝗢𝗧, a CRISPR-Cas9-based tool to activate hidden biosynthetic gene clusters. This has already led to the discovery of 39 new natural products in 4 classes!
#AMR #DrugDiscovery #CRISPR-Cas9 #BGC #ACTIMOT

Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and DZIF have developed a method called #ACTIMOT to harness biosynthetic gene clusters for the production of new active agents and accelerate the discovery of new medicines. @helmholtzhzi.bsky.social

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