Advisor Tom Linz standing next to PhD Candidate Jessica Halter inside Schaap Lecture Hall

#NextStopPhD! Jessica Halter, of the Linz Lab, gave her 4th year talk on: "Protein Structure Characterization Using Microfluidic Thermal Gel Electrophoresis." Brava, Jessica! #wsuchemistry #AnaChem #ChemSky #phdlife

Excellent teamwork from Wayne State University’s Fehl, Chekmenev, and @sadagurski.bsky.social, @karmanoscancer.bsky.social, @thomas-theis.bsky.social, & Southern Illinois University, Carbondale (SIUC). #AnaChem #spectroscopy

Tom Linz in Schaap Lecture Hall

WSU Chemistry’s Professor Tom Linz, gave today’s Frontiers Seminar on: “High-Sensitivity Microfluidics to Characterize Biological Heterogeneity.” Great to hear about the latest research from the Linz Lab. #wsuchemistry #AnaChem #Chemsky

SWIEET—a salt-free alternative to QuEChERS - Analytical and Bioanalytical Chemistry The efficient extraction of various analytes from a wide spectrum of matrices with organic solvents is still a great challenge in analytical chemistry. Especially polar and charged compounds are hard ...

This is a sweet (LOL) refinement of QUECHERS. Sounds very promising.
#AnaChem #MassSpec
link.springer.com/article/10.1...

First day back in the lab yesterday and, predictably, I had to spend half my day cleaning, remaking stock solutions, tracking down borrowed or stolen equipment, replacing broken things and sorting out the myriad technical problems which emerge and fester in my absence.
#LCMS #AnaChem #BioChem

It always amazes me when I try to reproduce a published analytical chemistry method and it completely fails. Not even a hint of the result reported in the paper. Just nothing.
#AnaChem

This Detroit-Based Founder And Scientist Developed An AI-Powered Device That Can Detect Pathogens On Surfaces Within Minutes - AfroTech

#WSUchemistry alum Darrell Marshall (WSU, BS, Analytical Chemistry, 2011) is featured @afro-tech.bsky.social for the work he’s doing with the Helios-1, his AI-powered device that detects pathogens on surfaces in minutes. #chemistryindetroit #BioTech #AnaChem

afrotech.com/darrell-mars...

Mary Rodgers giving a talk at the 2025 ANACHEM symposium

Mary Rodgers receiving an award at the 2025 ANACHEM symposium

More photos from #ANACHEM2025! Plenary Lecturer, Mary Rodgers was presented with the Anachem Award by Ratan Kukreja, the President of Anachem. #wsuchemistry #AnaChem #chemistryindetroit #ChemSky

1 person receiving an award

Group of 8 WSU Chemistry students at the 2025 ANACHEM Symposium

1 person giving a research talk on a stage

6 members of the Linz Lab at the 2025 ANACHEM Symposium

#WSUChemistry was well represented at this year’s ANACHEM Symposium yesterday. Mary T. Rodgers was the Plenary Speaker and the 2025 #ANACHEM Award Recipient. Jessica Halter, of the Linz Lab, won best presentation award.

Congratulations to Dr. Rodgers and Jessica on their achievements! #ChemSky

Host,Tom Linz standing next to guest lecturer Michael Bowser

Many thanks to Michael Bowser for visiting our campus and giving a seminar on his research into micro free-flow electrophoresis. #AnaChem #wsuchemistry #ChemTalk #ChemSky

2 people holding award certificates

Brice Vanness and Sethma Wijesinghe are recipients of the David F. Boltz Award in Analytical Chemistry. Congratulations! #wsuchemistry #ChemSky #AnaChem #MotivationMonday

2 people holding award certificates

Jaden Stanley and Liz Ballmann are recipients of the 2025 American Chemical Society Division of Analytical Chemistry Award. Congratulations! #wsuchemistry #WarriorWednesday #AnaChem #HonorsConvo2025 #ChemSky

#WSUchemistry’s Linz Lab had their annual summer celebration over the weekend. Good food and good times shared with good people. #AnaChem #ChemSky

1 person standing next to a research poster at a conference

5 people standing next to each other at a conference

Pictures from #Pittcon2025 – Sethma Wijesinghe presented her research at the international analytical conference. And look who our #AnaChem students ran into - @luolab-utah.bsky.social! #wsuchemistry #WarriorWednesday #ChemSky

3 people standing holding a framed object

Happy #WarriorWednesday from the Rodgers Lab! #wsuchemistry #chemistryindetroit #AnaChem #ChemSky

Flier for Chemistry and Food Tuesdays

Save the date! Chemistry & Food Tuesdays welcomes Patrick Weigand on Tuesday, March 4th, 12:30-1:30 pm, room 111, Chemistry. #wsuchemistry #AnaChem #lunchandlearn #ChemSky

Integrating Particle Motion Tracking into Thermal Gel Electrophoresis for Label-Free Sugar Sensing Bioanalytical sensors are adept at quantifying target analytes from complex sample matrices with high sensitivity, but their multiplexing capacity is limited. Conversely, analytical separations afford great multiplexing capacity but typically require analyte labeling to increase sensitivity. Here, we report the development of a separation-based sensor to sensitively quantify unlabeled polysaccharides using particle motion tracking within a microfluidic electrophoresis platform. Carboxymethyl dextran (20 kDa) was spiked into Pluronic thermal gel along with fluorescent nanoparticles (200 nm diameter) and loaded into single-channel microfluidic devices. Upon voltage application, the soluble sugar enriched into a concentrated band that induced motion of the insoluble particles as it passed. Bead displacement was tracked over time to produce electropherograms where peak areas were proportional to analyte concentrations. Key studies herein established the range of acceptable operating conditions (e.g., gel concentration, temperature) to characterize how the temperature-dependent rigidity of thermal gel influenced the analysis. Data processing strategies were then evaluated to identify conditions (e.g., exposure intervals, particle averaging, motion directionality) to maximize sensitivity. The quantitative response of the method was evaluated over a broad concentration range (0.5–5000 nM) where detection limits were found to be 520 pM for the 20 kDa sugar, providing a 106-fold superior mass LOD than a gold standard UV–vis absorbance method. Studies into the detection mechanism found that sensitivity was dependent on the molecular weight of the sugar as larger sugars produced greater responses. Collectively, these studies established best practices for integrating particle sensing into thermal gel separations for label-free polysaccharide quantitation.

An exciting start to the New Year by the Linz Lab! Mario Cornejo and Tom Linz describe the development of a label-free sensor to characterize polysaccharides in #ACSsensors. #wsuchemistry #AnaChem #chemistryindetroit #ChemSky

pubs.acs.org/doi/full/10....

4 people standing with the Wayne State mascot in the atrium of the chemistry building

Happy #WarriorWednesday 💚💛 #wsuchemistry #LinzLab #AnaChem #ChemistryInDetroit #ChemSky