Integrated analysis of single-cell RNA-seq and ATAC-seq in lens epithelial cells: Unveiling the role of ATF6 as a key transcription factor

#SingleCellAnalysis reveals #ATF6 drives #EpithelialMesenchymalTransition in #LensEpithelialCells, promoting #fibrosis & #cataract progression; inhibiting ATF6 reduces #STAT3 activation, highlighting ATF6–TAK1 signaling as a therapeutic target.
#OpenAccess: doi.org/10.1016/j.ge...