Patient education on #glucocorticoid stress dosing is key to the effective prevention of #adrenal #crises and their associated morbidity and mortality. All patients with #Addison’s disease should be given a steroid emergency card thelancet.com/journals/lan...
#Addison's disease

#MedSky #EndoSky

Adrenocortical carcinoma: a practical guide for clinicians Adrenocortical carcinoma is a rare endocrine malignancy. The management of patients with adrenocortical carcinoma is challenging for several reasons, including its heterogeneous but frequently aggress...

#Adrenocortical #carcinoma poses unique challenges to physicians, who must tackle both tumour progression and hormone secretion, and it considerably affects life expectancy thelancet.com/journals/lan...
#ACC #adrenal
#OpenAccess

#MedSky #EndoSky #OncSky

Advances in CT & MR have contributed to improved characterisation of #adrenal masses, & novel radiopharmaceuticals are being developed for molecular characterisation & disease subtyping www.thelancet.com/journals/lan...
#phaeochromocytoma #paragangliomas #PPGLs
#adrenocortical #carcinoma

#EndoSky

The first presentation of #Addison's disease to health-care services is often a life-threatening #adrenal #crisis, occurring in up to 50% of people with the condition www.thelancet.com/journals/lan...
#primary #adrenal #insufficiency

#MedSky #EndoSky

When an Adrenal Mass Isn’t Cancer: A Rare Case of Mycobacterium genavense Mimicking a Neuroendocrine Tumor Abstract. An adrenal mass is an abnormal growth or tumor that develops in one or both adrenal glands. These can be benign or malignant. They are common, wi

When an Adrenal Mass Isn’t Cancer: A Rare Case of Mycobacterium genavense Mimicking a Neuroendocrine Tumor. Read more in #JCEMCaseReports: bit.ly/4slXvJ3 #Infection #adrenal #Neuroendocrine @endocrinesociety.bsky.social

Patient education on #glucocorticoid #stress #dosing is key to the effective prevention of #adrenal #crises and their associated morbidity and mortality thelancet.com/journals/lan...
#Addison's disease
primary #adrenal insufficiency

#MedSky #EndoSky

Adrenal tumours are commonly encountered in every endocrinology practice and related subspecialties nowadays, and require the most accurate evidence-based management, treatment, and follow-up thelancet.com/journals/lan...
#adrenal #tumour
#phaeochromocytomas #paragangliomas #PPGLs

#MedSky #EndoSky

Due to its vague presentation, diagnosis of #Addison's disease is often delayed, and in some cases, individuals present in adrenal crisis www.thelancet.com/journals/lan...
#adrenal #insufficiency

#MedSky #EndoSky

Starting the day off right
#FellowArt #wellness #adrenal
@cudeptofmedicine.bsky.social

Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion MACS represents a metabolic continuum between NFAT and adrenal CS. Increased activity of the adrenal enzyme 11β-hydroxylase (CYP11B1), which catalyses key steps in cortisol and 11-oxygenated androgen ...

Published in @ebiomedicine.bsky.social

Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion www.thelancet.com/journals/ebi...
non-functioning #adrenal #tumours
#Cushing's syndrome
#OpenAccess

#MedSky #EndoSky

Endocrine Grand Rounds: Dr Gary Hammer @garydouglashammer.bsky.social from U Michigan presented on drug discovery for rare disease, focused on #adrenocorticalcancer #ACC. #adrenal Lessons learned: Be brave and bold. Perseverance is key. Discovery is iterative.

More liberal use of bilateral adrenalectomy for bilateral adrenal tumours with cortisol excess Bilateral adrenal tumours with cortisol hypersecretion represent a common clinical challenge. Adrenal incidentalomas are detected in approximately 4% of abdominal imaging studies, with prevalence incr...

Linked Comment by Quan-Yang Duh & Michelle B Mulder:
More liberal use of bilateral adrenalectomy for bilateral adrenal tumours with cortisol excess thelancet.com/journals/lan...
#bilateral #adrenal #tumours #adrenalectomy #cortisol excess

#MedSky #EndoSky #OncSky

Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study Although mortality and cardiovascular event rates were similar across treatments, surgery led to better biochemical control and more favourable comorbidity outcomes.

Although mortality and cardiovascular event rates were similar across treatments, surgery led to better biochemical control and more favourable comorbidity outcomes thelancet.com/journals/lan...
#bilateral #adrenal #tumours #adrenalectomy #cortisol excess

#MedSky #EndoSky #OncSky

Patient education on #glucocorticoid stress dosing is key to the effective prevention of #adrenal #crises and their associated morbidity and mortality www.thelancet.com/journals/lan...
#Addison's disease
#adrenal insufficiency

#MedSky #EndoSky

Adrenal tumour imaging: clinical, molecular, and radiomics perspectives Adrenal tumours have become a common incidental finding in the radiological evaluation of patients. Estimates suggest that 1–10% of the general population currently harbours an adrenal tumour, peaking...

For much of the 20th century, the diagnosis of #adrenal #tumours, defined as enlarged or atypical-appearing adrenal lesions that can be benign or malignant, relied on clinical suspicion of large palpable masses, hormonal manifestations, or autopsy findings www.thelancet.com/journals/lan...

#EndoSky

Clinical features, investigation, and management of Addison's disease thelancet.com/journals/lan...
#Addison's disease
#adrenal insufficiency
#adrenal crisis

#MedSky #EndoSky

#SimulAdren is a simulation program for the #hypothalamus - #pituitary - #adrenal feedback control, an essential physiological motif. It is written in #Object_Pascal and helps to understand life-threatening diseases.

Clinical features, investigation, and management of Addison's disease Addison's disease is the manifestation of adrenal glucocorticoid and mineralocorticoid deficiency from T-cell mediated destruction of the adrenal cortex, and is the commonest cause of primary adrenal ...

Health-care providers should consider #Addison's disease as a differential in a wide variety of presentations, and understand the correct interpretation and limitations of widely available cortisol assays thelancet.com/journals/lan...
#adrenal insufficiency
#adrenal crisis

#MedSky #EndoSky

Despite oral corticosteroid replacement therapy, people with #Addison's disease have increased mortality in addition to reduced HRQoL and working ability thelancet.com/journals/lan...
#adrenal insufficiency
#adrenal crisis

All patients with #Addison’s disease should be given a steroid emergency card and provided with and trained to use a glucocorticoid injection kit www.thelancet.com/journals/lan...
#adrenal insufficiency
#adrenal crisis

Addison's disease is the manifestation of adrenal glucocorticoid and mineralocorticoid deficiency from T-cell mediated destruction of the adrenal cortex, and is the commonest cause of primary adrenal insufficiency in adults www.thelancet.com/journals/lan...
#adrenal insufficiency

#MedSky #EndoSky

More liberal use of bilateral adrenalectomy for bilateral adrenal tumours with cortisol excess Bilateral adrenal tumours with cortisol hypersecretion represent a common clinical challenge. Adrenal incidentalomas are detected in approximately 4% of abdominal imaging studies, with prevalence incr...

Quan-Yang Duh & Michelle B Mulder comment on:
More liberal use of bilateral #adrenalectomy for bilateral #adrenal #tumours with #cortisol excess thelancet.com/journals/lan...
#cardiometabolic #morbidity #mortality
#adrenal crises

#MedSky #EndoSky #OncSky

Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study Although mortality and cardiovascular event rates were similar across treatments, surgery led to better biochemical control and more favourable comorbidity outcomes.

New—Effect of surgical versus conservative management on #cardiovascular outcomes in patients with #bilateral #adrenal #tumours and #cortisol excess: an international, retrospective cohort study thelancet.com/journals/lan...
#cardiometabolic #morbidity #mortality
#adrenal crises

#MedSky #EndoSky

Adrenal tumours are commonly encountered in every endocrinology practice and related subspecialties nowadays, and require the most accurate evidence-based management, treatment, and follow-up www.thelancet.com/journals/lan...
#adrenal #tumours

#MedSky #EndoSky #OncSky

A pleasure and a honour to host past #ENS@T President Prof Guillaume Assie from @hopitalcochin.bsky.social in Paris at @unibirmingham.bsky.social
Great opportunity to hear him talking about #genomics 🧬 in #endocrinetumours #adrenaltumours 👏and #networking with our #adrenal team!

#Adrenocortical #carcinoma poses unique challenges to physicians, who must tackle both tumour progression and hormone secretion, and it considerably affects life expectancy thelancet.com/journals/lan... #ACC #adrenal
#OpenAccess

#MedSky #EndoSky #OncSky

Have my first cold since starting steroid, and getting sick while on a daily steroid is crazy! Cold symptoms are weirdly muted but #adrenal symptoms turned up to 11. Makes it really difficult to accurately judge both dosing and pacing my daily activities. #ChronicIllness

#Adrenocortical #carcinoma is a rare malignancy, in contrast to benign #adrenal tumours, which are among the most common human neoplasias with a prevalence of greater than 3% in adults older than 50 years www.thelancet.com/journals/lan...
#ACC
#OpenAccess

#MedSky #EndoSky #OncSky

Adrenal tumours are commonly encountered in every endocrinology practice and related subspecialties nowadays, and require the most accurate evidence-based management, treatment, and follow-up www.thelancet.com/journals/lan...
#adrenal #tumours

#MedSky #EndoSky #OncSky

🚨 Good news! Registrations are open for our 1st #educational Webinar on latest advances in #genetics of #adrenal #tumours. Expect lectures from excellent international speakers and case presentations from early careers. Programme & links: ensat.org/event-6456168 #EndoSky #MedSky