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Bilateral Adrenal Metastases From Breast Cancer 14 Years After Remission: Diagnostic Value of “Adrenal Thickening”. Read more in #JCEMCaseReports: bit.ly/4ry306n #AdrenalThickening #AdrenalMetastasis #BreastAdenocarcinoma @endocrinesociety.bsky.social

Severe hypomagnesemia and secondary hypocalcemia associated with vonoprazan in a patient with type 2 diabetes Abstract. Hypomagnesemia is a well-known complication of long-term proton pump inhibitor usage; the stronger acid-suppressive effect of potassium-competiti

Severe hypomagnesemia and secondary hypocalcemia associated with vonoprazan in a patient with type 2 diabetes. Read more in #JCEMCaseReports: bit.ly/4rqN5Xz #diabetes #Hypocalcemia #Vonoprazan @endocrinesociety.bsky.social

Addison-like Clinical Phenotype Without Adrenal Insufficiency: A Rare Manifestation of Pernicious Anemia Abstract. Severe vitamin B12 deficiency can clinically mimic Addison disease, with hyperpigmentation despite preserved adrenal function. We report a 34-yea

Addison-like Clinical Phenotype Without Adrenal Insufficiency: A Rare Manifestation of Pernicious Anemia. Read more in #JCEMCaseReports: bit.ly/4bamN7f #AddisonDisease #Hyperpigmentation #Anemia @endocrinesociety.bsky.social

When an Adrenal Mass Isn’t Cancer: A Rare Case of Mycobacterium genavense Mimicking a Neuroendocrine Tumor Abstract. An adrenal mass is an abnormal growth or tumor that develops in one or both adrenal glands. These can be benign or malignant. They are common, wi

When an Adrenal Mass Isn’t Cancer: A Rare Case of Mycobacterium genavense Mimicking a Neuroendocrine Tumor. Read more in #JCEMCaseReports: bit.ly/4slXvJ3 #Infection #adrenal #Neuroendocrine @endocrinesociety.bsky.social

Mild Autonomous Cortisol Secretion in Congenital Adrenal Hyperplasia Managed With Mini Back Scope Adrenalectomy Abstract. A 55-year-old woman, diagnosed with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH) at age 7 years in the mid-Atlantic United Stat

Mild Autonomous Cortisol Secretion in Congenital Adrenal Hyperplasia Managed With Mini Back Scope Adrenalectomy. Read more in #JCEMCaseReports: bit.ly/4rr1iEV #Sepsis #SepticShock #Inflammation @endocrinesociety.bsky.social

Acute Autonomic Sensory Neuropathy Causing Severe Hyponatremia: A Rare Cause of Syndrome of Inappropriate Antidiuresis Abstract. A 25-year-old woman had experienced dizziness and numbness following a recent fever accompanied by upper respiratory symptoms. She was subsequent

Acute Autonomic Sensory Neuropathy Causing Severe Hyponatremia: A Rare Cause of Syndrome of Inappropriate Antidiuresis. Read more in #JCEMCaseReports: bit.ly/4aEueSn #Hyponatremia #AcuteAutonomicSensoryNeuropathy @endocrinesociety.bsky.social

Insulinoma Unmasked By Tirzepatide: A Rare Case of Postprandial Hypoglycemia In a Nondiabetic Patient Abstract. A 63-year-old woman with obesity presented with severe postprandial hypoglycemia that worsened after starting tirzepatide for weight loss. Furthe

Insulinoma Unmasked By Tirzepatide: A Rare Case of Postprandial Hypoglycemia In a Nondiabetic Patient. Read more in #JCEMCaseReports: bit.ly/4ta09mr #insulinoma #Tirzepatide #NeuroendocrineTumor @endocrinesociety.bsky.social

Mechanism and Context: Making Sense of Adverse Events With GLP-1-based Therapy Glucagon-like peptide 1 (GLP-1)-based therapies have reshaped the clinical approach to type 2 diabetes and obesity [1]. Long-acting GLP-1 receptor agonists

Mechanism and Context: Making Sense of Adverse Events With GLP-1-based Therapy. Read more in #JCEMCaseReports: bit.ly/4sPm2qX #AdverseEvents #diabetes #GLP-1BasedTherapy #obesity @endocrinesociety.bsky.social

An Unusual Etiology of Recurrent Parathyroid Hormone–Independent Hypercalcemia Abstract. The diagnosis of parathyroid hormone (PTH)-independent hypercalcemia can be challenging due to its heterogeneous etiology. We report a case of a

An Unusual Etiology of Recurrent Parathyroid Hormone–Independent Hypercalcemia. Read more in #JCEMCaseReports: bit.ly/4sWbcQ6 #Hypercalcemia #Sarcoidosis #ParathyroidHormone @endocrinesociety.bsky.social

Cabergoline-Induced Gambling Causing Increased Adrenal Crisis Episodes Abstract. Dopamine agonists have been used in the treatment of acromegaly, but they are modestly effective and are rarely associated with impulse control d

Cabergoline-Induced Gambling Causing Increased Adrenal Crisis Episodes. Read more in #JCEMCaseReports: bit.ly/4pNVtj6 #acromegaly #DopamineAgonists #CabergolineImpulseControlDisorders @endocrinesociety.bsky.social

The Triple Hormone Enigma: Pituitary Macroadenoma With Bilateral Cortisol-Androgen Secreting Adenomas. Read more in #JCEMCaseReports: bit.ly/44uokRR #PlurihormonalPituitaryAdenoma #Hyperandrogenism @endocrinesociety.bsky.social

Rare Causes of Hypoglycemia—Lessons from Case Reports Hypoglycemia in individuals without exogenous insulin use is uncommon and heterogeneous, with an estimated frequency of 36 per 10 000 hospital admissions [

Rare Causes of Hypoglycemia—Lessons from Case Reports. Read more in #JCEMCaseReports: bit.ly/4pdD4wB #hypoglycemia #insulinoma #WhippleTriad @endocrinesociety.bsky.social

SALL1 Is an Orchestrator of Uterine Receptivity in Part via Titration of Estrogen Signaling Abstract. SALL1 is a critical regulator of embryonic development across a wide swath of tissues, including vital organs, but little is known about its func

SALL1 Is an Orchestrator of Uterine Receptivity in
Part via Titration of Estrogen Signaling. Read more in #JCEMCaseReports: bit.ly/3KcYk6k
#implantation #decidualization #SALL1 @endocrinesociety.bsky.social

Adult Hypophosphatasia in a Middle-Aged Patient With Recurrent Fractures: Prevention of New Fractures With Asfotase Alfa Abstract. Hypophosphatasia (HPP) is a rare inherited bone disorder with systemic symptoms, which vary depending on the time of onset and other factors. It

Adult Hypophosphatasia in a Middle-Aged Patient With Recurrent Fractures: Prevention of New Fractures With Asfotase Alfa. Read more in #JCEMCaseReports: bit.ly/4pocyAk #adulthypophosphatasia #asfotasealfa #alkalinephosphatase @endocrinesociety.bsky.social

Diagnostic Journey in the Recognition of Oncogenic Osteomalacia Abstract. A 73-year-old woman with a remote history of successfully treated primary hyperparathyroidism was referred to our office because of multiple skel

Diagnostic Journey in the Recognition of Oncogenic Osteomalacia. Read more in #JCEMCaseReports: bit.ly/47EgPbt #oncogenicosteomalacia #tumor-inducedosteomalacia #fibroblastgrowthfactor23 @endocrinesociety.bsky.social

Immune Checkpoint Inhibitor Endocrinopathies—Insights From 3 Unusual Cases Immune checkpoint inhibitors (ICIs) are monoclonal antibody drugs that have revolutionized cancer therapy and led to dramatically improved survival for agg

Immune Checkpoint Inhibitor Endocrinopathies—Insights From 3 Unusual Cases. Read more in #JCEMCaseReports: bit.ly/494cHnO #Hypophysitis #Type1Diabetes #primaryadrenalinsufficiency @endocrinesociety.bsky.social

2025 Clinical Pearls from JCEM Case Reports Watch Clinical Pearls from JCEM Case Reports with presentations from authors and expert commentary that occurred at ENDO 2025. Then visit our Journals site to read the article: https://bit.ly/4nEB2VG Please note that this session is only available for...

2025 Clinical Pearls from JCEM Case Reports | Watch presentations from authors and expert commentary that occurred at ENDO 2025 (https://bit.ly/4hGTsmt Then visit our Journals site to read the article (https://bit.ly/4nEB2VG #JCEMCaseReports #endocrinology #EndoSky @endosocjournals.bsky.social

Concomitant Immune Checkpoint Inhibitors Induced Central and Primary Adrenal Insufficiency: A Diagnostic Challenge. Read more in #JCEMCaseReports: bit.ly/42UM6pd #ImmuneCheckpointInhibitors #Hypophysitis #Adrenalitis

Hereditary Hemochromatosis Type 2A Presenting With Hypogonadism, Diabetes, and Osteoporosis in a Young Woman Abstract. Hereditary hemochromatosis type 2A (juvenile hemochromatosis) is a rare autosomal recessive disorder caused by mutations in the HJV gene. It resu

Hereditary Hemochromatosis Type 2A Presenting With Hypogonadism, Diabetes, and Osteoporosis in a Young Woman. Read more in #JCEMCaseReports: bit.ly/49jhHF1 #DiabetesMellitus #osteoporosis #JuvenileHemochromatosis @endocrinesociety.bsky.social

Glycemic Derangements With Capivasertib—From Hyperglycemia to Diabetic Ketoacidosis: A Report of 3 Cases Abstract. Capiversatib is a pan-Ak strain transforming inhibitor used in combination with fulvestrant for the treatment of hormone receptor-positive advanc

Glycemic Derangements with #Capivasertib—From Hyperglycemia to #DiabeticKetoacidosis: A Report of Three Cases. Read more in #JCEMCaseReports: bit.ly/4n3isFA #InsulinResistance @endocrinesociety.bsky.social

Clinical Pearls From JCEM Case Reports: ENDO 2025 On July 14, 2025, the journal hosted the third annual “Clinical Pearls from JCEM Case Reports” at the annual Endocrine Society meeting in San Francisco, Ca

Clinical Pearls From JCEM Case Reports: ENDO 2025. Read more in #JCEMCaseReports: bit.ly/4nw1fp9 #ENDO2025 @endocrinesociety.bsky.social

Liver Transplantation as a Metabolic Treatment in Glycogen Storage Disease Type Ia. Read more in #JCEMCaseReports: bit.ly/46TWakA #osteoporosis #livertransplantation #hepaticadenoma @endocrinesociety.bsky.social

Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes AbstractContext. Obesity and insulin resistance in men are linked to decreased testosterone and increased estradiol (E2) levels. Aromatase (ARO) converts t

Altered expression of #aromatase and estrogen receptors in adipose tissue from men with obesity or type 2 diabetes. Read more in #JCEMCaseReports: bit.ly/4ngNISd #estradiol #obesity #T2D @endocrinesociety.bsky.social

What did you think of our Thematic Issue on recent articles by ENDO 2025 invited speakers? Read our special collection of journal articles, published in 2025 or late 2024, from our journals: bit.ly/3CaZyLy #JCEM #JES #JCEMCaseReports #Endocrinology #ENDO2025

Fatal, Fulminant, Necrotizing Pancreatitis Associated With Recent Tirzepatide Initiation Abstract. As obesity is increasing in prevalence and its associated morbidity and mortality are escalating worldwide, medications like tirzepatide are freq

Fatal, fulminant, necrotizing #pancreatitis associated with recent #tirzepatide initiation
doi.org/10.1210/jcem.... Featured in #JCEMCaseReports #OpenAccess
@endocrinesociety.bsky.social

Functional Suppression of a Prolactinoma by a Dopamine-Secreting Paraganglioma Abstract. Prolactin-secreting pituitary adenomas are typically treated with dopamine agonists to inhibit prolactin secretion and reduce tumor size. Dopamin

Functional suppression of a #prolactinoma by a dopamine-secreting #paraganglioma. Featured in #JCEMCaseReports. #OpenAccess #dopamine
academic.oup.com/jcemcr/artic...
@endocrinesociety.bsky.social

Transient Blindness in Metformin-associated Lactic Acidosis: Resolution With Supportive Care Abstract. Metformin remains the first-line pharmacologic treatment for type 2 diabetes mellitus due to its well-established efficacy and safety profile. Ho

Transient #Blindness in #Metformin -associated Lactic #Acidosis: Resolution With Supportive Care. Featured in #JCEMCaseReports #T2D
doi.org/10.1210/jcem...
@endocrinesociety.bsky.social

An Unusual Case of Factitious Disorder Manifesting as Hypercalcemia Mediated by Exogenous Calcitriol Abstract. Excessive 1, 25-dihydroxy vitamin D (calcitriol) is a pathophysiological cause of hypercalcemia. This form of hypercalcemia is seen in autoimmune

An unusual case: factitious disorder manifesting as #hypercalcemia mediated by exogenous #calcitriol. Featured case report in #JCEMCaseReports. #OpenAccess #PTH
@endocrinesociety.bsky.social
doi.org/10.1210/jcem...

Refractory Hypoglycemia Secondary to the Warburg Effect in Diffuse Large B-Cell Lymphoma Abstract. Spontaneous and refractory hypoglycemia in malignancy poses diagnostic challenges, since its exact underlying mechanisms remain unclear. A 62-yea

Refractory #hypoglycemia secondary to the #Warburg effect in diffuse large B-cell #lymphoma. Featured case in #JCEMCaseReports. #OpenAccess
doi.org/10.1210/jcem...
@endocrinesociety.bsky.social

Bilateral #adrenal #leiomyomas in a #pediatric patient. Featured item in #JCEMCaseReports describes successful management of these rare benign tumors #OpenAccess
doi.org/10.1210/jcem...
@endocrinesociety.bsky.social