Immune Checkpoint Inhibitor Endocrinopathies—Insights From 3 Unusual Cases Immune checkpoint inhibitors (ICIs) are monoclonal antibody drugs that have revolutionized cancer therapy and led to dramatically improved survival for agg

Immune Checkpoint Inhibitor Endocrinopathies—Insights From 3 Unusual Cases. Read more in #JCEMCaseReports: bit.ly/494cHnO #Hypophysitis #Type1Diabetes #primaryadrenalinsufficiency @endocrinesociety.bsky.social

Concomitant Immune Checkpoint Inhibitors Induced Central and Primary Adrenal Insufficiency: A Diagnostic Challenge. Read more in #JCEMCaseReports: bit.ly/42UM6pd #ImmuneCheckpointInhibitors #Hypophysitis #Adrenalitis

"In cases of severe, refractory or worsening #hypophysitis after initial therapy with #glucocorticoids, non-glucocorticoids immunosuppressive therapy could be a safe and effective alternative to control symptoms and #pituitary stalk thickening." -- Janaki Vakharia, MD. #ENDO2025 #EndoSky

A figure showing the possible underlying mechanism of ICI-related anti-PIT1 hypophysitis.

From our May issue: a Comment from Yutaka Takahashi and colleagues exploring anti-PIT1 #hypophysitis after #immune checkpoint inhibitor treatment rdcu.be/ehEsM

Response to commentary: "Primary #Hypophysitis and the benefits of Glucocorticoids, a still unresolved question’’ by Aysa Hacioglu et al

EJE Volume 192, Issue 1, January 2025
👉 doi.org/10.1093/ejen...
ESE Members free access via 👉 my.ese-hormones.org