The global incidence of #alkaptonuria (AKU) varies substantially. Overall, AKU affects ~1 in 250,000 to 1,000,000 individuals worldwide. https://www.nature.c

Cycle Pharmaceuticals Partners with LeMed for Exclusive Distribution of HARLIKU™ Treatment in the U.S. Cycle Pharmaceuticals has chosen LeMed Specialty Pharmacy for exclusive U.S. distribution of HARLIKU™, the sole FDA-approved treatment for Alkaptonuria. This partnership aims to enhance patient care.

Cycle Pharmaceuticals Partners with LeMed for Exclusive Distribution of HARLIKU™ Treatment in the U.S. #United_States #Bronx #HARLIKU™ #Alkaptonuria #Cycle_Pharmaceuticals

🥳New issue means new cover image🥳

Ochronotic #pigmentation is shown within the perichondrium surrounding hyaline #cartilage from the secondary #bronchus of an individual with #alkaptonuria.

Hughes et al.'s investigation of alkaptonuria, available now: doi.org/10.1111/joa....

Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism.

Glad this is finally out. Using pharmacokinetic modeling we show that #nitisinone, an FDA-approved drug 4 #Tyrosinemia & #Alkaptonuria, kills #Anopheles mosquitoes, outperforming #Ivermectin. Grateful to all primary author’s & fantastic collaborators!

www.science.org/doi/10.1126/...

🌍💙 today is #RareDiseaseDay — a moment to raise awareness and support research for rare conditions.We study #Alkaptonuria (AKU) - ochronosis. Rare diseases may be uncommon, but research is key to better care & solutions.

Juliette Hughes AKU Workshop 2024 | International Patient Workshop showcases Liverpool as the global hub for the rare disease AKU | Faculty of Health and Life Sciences | University of Liverpool ...

It is always an absolute pleasure to participate in #alkaptonuria patient workshops 😄 the last was held in November in #Liverpool (UK), organised by the AKU Society - see my new blog ⬇️

@livuniresearch.bsky.social @livuni-ilcams.bsky.social

www.liverpool.ac.uk/health-and-l...

New publication out in Journal of anatomy with details of tissues such as ear ossicles, TMJ and sclera not reported before #anatomy #journalofanatomy #alkaptonuria

An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone Examination of an alkaptonuria body highlights the susceptibility of all cartilage types and associated perichondrium to ochronotic pigmentation and the heterogeneity of ochronotic pigment distributi...

Just in time for Christmas 🎄
New paper in @journalofanatomy.bsky.social

Insights into #ochronosis in the #raredisease #alkaptonuria, made possible through the invaluable gift of body donation. Such a privilege working on this project!

onlinelibrary.wiley.com/doi/full/10....