Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis - Nature Metabolism A uridine-sensitized CRISPR-Cas9 screening identifies demethoxy-CoQ as an alternative electron acceptor in the absence of CoQ, and NUDT5 as a regulator of de novo pyrimidine synthesis via its interact...

Mais pas seulement! #Agir directement sur cet élément clé pourrait permettre de rendre les cellules résistantes à nouveau sensibles aux #analogues de #nucléotides.
🔗 www.nature.com/articles/s42...

@natureportfolio.nature.com @pagliarini-lab.bsky.social @zakbaker.bsky.social

Vitamin K Analogues May Help Transform the Treatment of Neurodegenerative Diseases｜Shibaura Institute of Technology SIT Shibaura Institute of Technology (Tokyo)

Supercharged Vitamin K could help the brain heal itself [via Shibaura Inst. of Tech] 🧪🥼🧠🩺⚕️

"findings highlight unique mechanisms underlying the #neuroprotective effects of #vitamin K and its analogues"

www.shibaura-it.ac.jp/en/headline/...

#analogues #brain #neurogenesis #health #medicine

Unlocking the Secrets of Ancient Estuarine Deposits In recent months, I had the opportunity to work on a project analysing subsurface data from a rock sequence previously interpreted as the product of an estuarine depositional environment. The client s...

"Unlocking the Secrets of Ancient Estuarine Deposits"
New article on the preserved sedimentary architecture of estuaries in the subsurface.
blogs.egu.eu/divisions/ss...
#estuaries #outcrops #analogues #sandbars #sandune #sedimentology #subsurface #architecture #reservoir

Les #analogues du #GLP-1 #altèrent la #qualité de la #préparation_intestinale #préalable à une #coloscopie ( #méta_analyse)

Analogues, by Airospace 7 track album

Airo always stays in rotation fr.
Goes hard if you don't know.

#AlbumOfTheDay
#Airospace
#Analogues
#Hiphop
#underground
#hiphopsky

Avondje uit vanavond naar the Analogues. Ze spelen de albums Abbey Road en Let it be volledig.
#analogues #afscheidstour
#beatles

If you have nothing better to do this afternoon, why not sit down with your favourite beverage and watch the #Analogues perform the whole four sides of the #Beatles #White_Album. Extraordinary!

https://youtu.be/g_Kh_L26604?feature=shared

As a Beatles fan of over 50 years, I have never seen a band perform a #Beatles cover better than the #Analogues. Here they perform the Golden Slumbers, Carry that Weight & The End segue from Abbey Road. Simply as close to the original sound as you can get. https://youtu.be/PkgaoG6Rd9w?feature=shared

Map showing rainfall anomalies globally for simulations of the AWI-ESM model with conditions 9,000 yr ago, during the North African Humid Period: increase in rainfall in the African Monsoon region.

2. Wetter intervals of the geological past (e.g., North African Humid Periods or #GreenSahara phases) are useful (partial) #analogues