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Flawed study on the antidepressant Paxil came with a cautionary note — if you knew how to find it When scientific journals publish expressions of concerns, they have an obligation to do so prominently, Ed Silverman writes.

Flawed study on the antidepressant Paxil came with a cautionary note — if you knew how to find it... statnews.com/pharmalot/20... #pharma #transparency #antidepressant #Paxil #clinicaltrials #medicaljournals #GSK #Elsevier

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JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. Study: web-based PETRUSHKA tool. Results: 17% discontinuation in PETRUSHKA tool vs. 27% in usual care at 8 weeks.

JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. Study: web-based PETRUSHKA tool. Results: 17% discontinuation in PETRUSHKA tool vs. 27% in usual care at 8 weeks.

📊 Research Summary: Among adults with major depressive disorder, use of a web-based decision-support tool reduced early #antidepressant discontinuation and improved symptoms compared with usual care.

ja.ma/4vDrqyT

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JAMA cover, April 14, 2026, Volume 335, Number 14. Research: "text@1219" A Decision-Support System to Personalize Antidepressant Treatment. Opinion: "text@1201" Menopausal Hormone Labels Should Rely on Evidence. Clinical Review & Education: "text@1250" Chronic Diarrhea.

JAMA cover, April 14, 2026, Volume 335, Number 14. Research: "text@1219" A Decision-Support System to Personalize Antidepressant Treatment. Opinion: "text@1201" Menopausal Hormone Labels Should Rely on Evidence. Clinical Review & Education: "text@1250" Chronic Diarrhea.

📌 Editor’s Choice from this week's issue of JAMA:

➡️ Chronic #Diarrhea Review,
➡️ Restrictive vs Liberal #ICU Physical Restraint,
➡️ Web-Based #Antidepressant Decision Tool, and more.

ja.ma/4cHXbPA

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JAMA cover: "Picking Antidepressants—Patient Preferences Beat Biomarkers" by Gregory E. Simon, MD, MPH. Article discusses antidepressant medication, remission rates, and personalized treatment research. Published online March 4, 2026.

JAMA cover: "Picking Antidepressants—Patient Preferences Beat Biomarkers" by Gregory E. Simon, MD, MPH. Article discusses antidepressant medication, remission rates, and personalized treatment research. Published online March 4, 2026.

💬 Editorial: Personalized #antidepressant selection using clinical criteria and patient preferences may yield better outcomes than biomarker-driven approaches for #depression.

ja.ma/4mt3dqF

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At the clinical level, the strongest evidence for #BLT concerns #seasonalaffectivedisorder, but data also indicate #antidepressant efficacy in major depressive disorder and #bipolardisorder, with an excellent tolerability profile.

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Press Release Bulletin | 7 April 2026 Welcome to Medianet’s daily media alert featuring a curated list of today's most newsworthy press releases handpicked by our editorial team. Today's highlights Tesla and Polestar sales surge as EV dem...

🔢 Today's Press Release Bulletin from Medianet 🔢
www.linkedin.com/pulse/press-...

#ElectricVehicles #UVRadiation #Pollution #Antidepressant #Vaccines #AustralianNews #pressrelease #pressreleasedistribution #australia #australianews #media #journalists #NewsletteroftheWeek

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📣Read our March newsletter.

Highlights include the PETRUSHKA trial using AI to personalise #antidepressant treatment, a Senior Research Nurse #vacancy supporting #dementia trials, and new evidence on the impact of the TUNE‑UP Clinic for treatment‑resistant #schizophrenia.

tinyurl.com/Issue25OHBRC

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PET imaging study reveals how ketamine relieves treatment-resistant depression – BioNews Central PET imaging study reveals molecular brain changes that explain ketamine’s rapid antidepressant effects. ...

#PETimaging study reveals molecular #BrainChanges that explain #ketamine’s rapid #antidepressant effects.
#DepressionTreatment #TreatmentResistantDepression #BrainImaging

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Now that is passion and energy to get lost in!

#passion #energy #whatido #creation #antidepressant

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JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. PETRUSHKA tool: 271 patients, Usual care: 269 patients. Rate of treatment discontinuation at 8 weeks: PETRUSHKA tool 17% vs Usual care 27%.

JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. PETRUSHKA tool: 271 patients, Usual care: 269 patients. Rate of treatment discontinuation at 8 weeks: PETRUSHKA tool 17% vs Usual care 27%.

📊 Research Summary: Among adults with major depressive disorder, use of a web-based decision-support tool reduced early #antidepressant discontinuation and improved symptoms compared with usual care.

ja.ma/3MJmaYY

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🤔What if choosing the right #antidepressant didn’t depend on trial and error?

New research shows an AI‑driven clinical decision‑support tool improves outcomes for people with #depression.

PETRUSHKA users were 40% less likely to stop treatment within eight weeks.

tinyurl.com/PetrushkaCRF

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🤔What if choosing the right #antidepressant didn’t depend on trial and error?

New research shows an AI‑driven clinical decision‑support tool improves outcomes for people with #depression.

PETRUSHKA users were 40% less likely to stop treatment within eight weeks.

tinyurl.com/PetrushkaAC

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JAMA cover, "Picking Antidepressants—Patient Preferences Beat Biomarkers" by Gregory E. Simon, MD, MPH. Published online March 4, 2026. Article discusses antidepressant medication and treatment personalization.

JAMA cover, "Picking Antidepressants—Patient Preferences Beat Biomarkers" by Gregory E. Simon, MD, MPH. Published online March 4, 2026. Article discusses antidepressant medication and treatment personalization.

💬 Editorial: Personalized #antidepressant selection using clinical criteria and patient preferences may yield better outcomes than biomarker-driven approaches for #depression.

ja.ma/4aOKZvL

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JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. PETRUSHKA tool: 271 patients, Usual care: 269 patients. Rate of treatment discontinuation at 8 weeks: PETRUSHKA tool 17% vs Usual care 27%.

JAMA Research Summary: A Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder. PETRUSHKA tool: 271 patients, Usual care: 269 patients. Rate of treatment discontinuation at 8 weeks: PETRUSHKA tool 17% vs Usual care 27%.

📊 Research Summary: Among adults with major depressive disorder, use of a web-based decision-support tool reduced early #antidepressant discontinuation and improved symptoms compared with usual care.

ja.ma/4l6OalT

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here's your dose of antidepressants 🐐 these little nuggets are too cute 🥰 #goats #goatfarm #babygoats #goatsky #farmsky #farm #antidepressant #mentalhealth

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Transcriptional profiles of antidepressant resistance across the corticolimbic pathway of chronically stressed mice - Neuropsychopharmacology Neuropsychopharmacology - Transcriptional profiles of antidepressant resistance across the corticolimbic pathway of chronically stressed mice

OUT NOW! Researchers Trevonn Gyles, Eric Parise, @neuroangelica-atb.bsky.social, et al. provide insight into gene networks contributing to #Antidepressant non-response & highlight a mechanistic framework for modeling antidepressant resistance in preclinical systems 👉 www.nature.com/articles/s41...

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Hallucinogen DMT an effective antidepressant in small clinical trial Effectiveness appears to correlate with self-described mystical experience.

#Hallucinogen #DMT an effective #Antidepressant in small clinical trial arstechnica.com/health/2026/...

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Hallucinogen DMT an effective antidepressant in small clinical trial https://arstechni.ca #antidepressant #clinicaltrial #hallucinogen #psychedelic #depression #Health #DMT

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New publication #Moods_Inserm Reinforcing our findings #5-HT4R as a promising strategy for faster-acting #anxiolytic #antidepressant #MentalHealth. Thanks @sofiacus.bsky.social for your microbiota perspective #GutBrainAxis & all collaborators!
@parissaclay.bsky.social www.nature.com/articles/s41...

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Can you tell: "Antidepressant drug or a Tolkien character?"
(Plus- penicillin)

Navigate nomenclature: roughlydaily.com/2026/02/12/w...

#alexanderfleming #antidepressant #antidepressants #charlesfletcher #culture #drugs #history #lordoftherings #medicine #penicillin #science #tolkien

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My #Kind of #Antidepressant! ... I just #LookUp and #Breathe!

#Clouds #Photography #EastCoastKin #Skyscape

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#antidepressant #ravenlyponderlust #420friends

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Mitochondria and Energetic Failures: A New Understanding of Antidepressant Withdrawal? An Interview With Chris Masterjohn Chris Masterjohn joins us to discuss the importance of our mitochondria, the role of serotonin in our body and whether a new understanding of antidepressant withdrawal is urgently needed.

Chris Masterjohn joins our #podcast to discuss how studying mitochondria could lead to a potential new understanding of #antidepressant withdrawal.

Read or listen on Mad in America: 🎧 buff.ly/ABR9cvE

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#Antidepressant withdrawal becomes a bigger problem (rising 10-fold) after 2 years of use, from new NHS study:
pubmed.ncbi.nlm.nih.gov/40404538

Evidence grade Low 3/10

More on stopping meds in our interview with lead author, Mark Horowitz:
www.thecarlatreport.com/articles/487...

#psychiatry

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I think my antidepressant helps with muscle pains - I was out for a few days and my bones hurt more. I'm not sure if that is the way to describe the feeling. #Effexor #antidepressant #musclepain

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Tricyclic antidepressants in treatment of depression #antidepressant #depression #mentalhealth
Tricyclic antidepressants in treatment of depression #antidepressant #depression #mentalhealth Tricyclic antidepressants in treatment of depression #antidepressant #depression #mentalhealth

Tricyclic antidepressants in treatment of depression #antidepressant #depression #mentalhealth ... Continue to: www.youtube.com/watch?v=7NHc...

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MultiSearch Tag Explorer MultiSearch Tag Explorer - Explore tags and search results by aéPiot

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Cabildo Abierto Una plataforma para discutir en serio, hecha en Argentina.

cabildoabierto.ar/perfil/aepiot.bsky.social

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