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#KetamineTherapy #MentalHealthCare #DepressionHelp #PTSDRecovery #TreatmentResistantDepression #MentalHealthAwareness #HolisticCare #InnovativeMedicine #AnxietyRelief #TraumaHealing #MindBodyCare #RothFamilyMed

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JAMA Psychiatry: RCT: A Ketogenic Diet for Treatment-Resistant Depression. Population: 26 men, 61 women, 1 nonbinary, mean age 42.1. Intervention: 88 participants randomized, 44 ketogenic diet group, 44 phytochemical group. Graph showing PHQ-9 score vs time since randomization.

JAMA Psychiatry: RCT: A Ketogenic Diet for Treatment-Resistant Depression. Population: 26 men, 61 women, 1 nonbinary, mean age 42.1. Intervention: 88 participants randomized, 44 ketogenic diet group, 44 phytochemical group. Graph showing PHQ-9 score vs time since randomization.

A 6-week #KetogenicDiet produced modest improvement in depressive symptoms vs control in adults with #TreatmentResistantDepression, with no difference in secondary outcomes and uncertain clinical relevance. ja.ma/4sTC96t

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#KetamineTherapy #MentalHealthCare #DepressionHelp #PTSDRecovery #TreatmentResistantDepression #MentalHealthAwareness #HolisticCare #InnovativeMedicine #AnxietyRelief #TraumaHealing #MindBodyCare #RothFamilyMed

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#KetamineTherapy #MentalHealthCare #DepressionHelp #PTSDRecovery #TreatmentResistantDepression #MentalHealthAwareness #HolisticCare #InnovativeMedicine #AnxietyRelief #TraumaHealing #MindBodyCare #RothFamilyMed

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JAMA Psychiatry info sheet. RCT: GH001 vs Placebo in Patients With Treatment-Resistant Depression. Population: 35 Male, 46 Female. Intervention: 81 patients randomized, 40 inhaled mebufotenin (GH001), 41 inhaled placebo. Findings: graph showing change from baseline.

JAMA Psychiatry info sheet. RCT: GH001 vs Placebo in Patients With Treatment-Resistant Depression. Population: 35 Male, 46 Female. Intervention: 81 patients randomized, 40 inhaled mebufotenin (GH001), 41 inhaled placebo. Findings: graph showing change from baseline.

Among adults with #TreatmentResistantDepression, single-day inhaled GH001 resulted in rapid, significant symptom reduction and remission vs placebo, with no severe adverse events and sustained effects over 6 months.

ja.ma/3Nme5ty

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TREATMENT RESISTANT
2026

#digitalcollage #queerart #queerartist #medication #mentalhealth #depression #treatmentresistantdepression #outsiderart #feminist #queer #horror #textart

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Alto raises $120m for resistant depression programme Alto Neuroscience has raised $120m that will fund pivotal trials of its recently acquired candidate for treatment-resistant depression.

NYSE-listed #AltoNeuroscience has raised $120 million in a private placement that will be used to advance its recently acquired candidate for #treatmentresistantdepression (TRD) into a pivotal trials programme. #financing

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Treatment-resistant doesn't mean hopeless. Spravato offers an FDA-approved path forward. 💜🩺✨

#MentalHealthCare #Spravato #Esketamine #TreatmentResistantDepression #OPMHS #Hope #MentalWellness

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PET imaging study reveals how ketamine relieves treatment-resistant depression – BioNews Central PET imaging study reveals molecular brain changes that explain ketamine’s rapid antidepressant effects. ...

#PETimaging study reveals molecular #BrainChanges that explain #ketamine’s rapid #antidepressant effects.
#DepressionTreatment #TreatmentResistantDepression #BrainImaging

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It’s encouraging to see awareness around treatment-resistant depression and evidence-based options like Spravato offered in a safe, supervised setting. Hope matters — and so does access to the right care. 💙
#MentalHealthAwareness #TreatmentResistantDepression #Spravato

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JAMA Psychiatry: RCT: A Ketogenic Diet for Treatment-Resistant Depression. Population: 26 Men, 61 Women, 1 Nonbinary. Intervention: 88 participants randomized. Findings: The KD group had greater improvement than the Phyto group after text@1 weeks. Mean change in PHQ-9 score.

JAMA Psychiatry: RCT: A Ketogenic Diet for Treatment-Resistant Depression. Population: 26 Men, 61 Women, 1 Nonbinary. Intervention: 88 participants randomized. Findings: The KD group had greater improvement than the Phyto group after text@1 weeks. Mean change in PHQ-9 score.

A 6-week #KetogenicDiet produced modest improvement in depressive symptoms vs control in adults with #TreatmentResistantDepression, with no difference in secondary outcomes and uncertain clinical relevance. ja.ma/4abkIpD

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Systems psychiatry arrives: biotypes, TRD staging, neuromodulation, ketamine & digital phenotyping 🧠📡⚙️💊📱🚀 @mdpiopenaccess.bsky.social #Neuroscience #PrecisionMedicine #Neurocircuitry #MajorDepressiveDisorder #TreatmentResistantDepression
Read for strategy, not slogans 📘➡️ doi.org/10.3390/biom...

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Nerve Stimulation Halts Depression In More Than 20% Of Patients, Clinical Trial Reports - Drugs.com MedNews FRIDAY, Jan. 16, 2026 Treatment-resistant depression might be eased using an implant that sends electrical pulses to one of the body s major nerve clusters, a n

New hope for treatment-resistant depression: chest implant sends electrical pulses to vagus nerve. 1 in 5 patients depression-free after 2 years, 69% showed meaningful improvement. Results sustained long-term, "highly atypical". #TreatmentResistantDepression www.drugs.com/news/nerve-s...

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Longitudinal Changes in Cortical Response Dynamics with Deep Brain Stimulation to the Subcallosal Cingulate for Treatment-Resistant Depression
Alagapan, S. et al.
Paper
Details
#DeepBrainStimulation #TreatmentResistantDepression #CorticalDynamics

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It's neither a moral failure nor a permanent condition.

There are DOZENS of effective next-step treatments: tDCS, TMS, ketamine/esketamine, ECT, augmentation strategies, etc. Many of them go into full remission after being labeled “treatment resistant.”👏

#TreatmentResistantDepression #MentalHealth

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Vor der Narkose machten die österreichische Anästhesistin und der bayrische Psychiater mir noch die linguistische Freude und diskutierten über Bedeutung und Aussprache von "Springinkerl". #EKT4TRD #TreatmentResistantDepression

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Hoher Besuch heute. Ein Professor aus New York, der führend in der EKT- und VNS-Forschung ist. Gemeinsam mit zwei AssistentInnen kam er um von meinen Erfahrungen mit diesen Behandlungsformen zu hören.
#EKT4TRD #VNS4TRD #TreatmentResistantDepression

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Depression Trusted Depression Specialist serving Palo Alto, CA. Contact us at 650-681-2900 or visit us at 206 California Ave, Palo Alto, CA 94306: Palo Alto Mind Body

Ketamine’s fast action makes it especially beneficial for treating patients who are suicidal or who have an acute depressive episode. It’s also effective for #treatmentresistantdepression and helps relieve physical #pain caused by depression. www.paloaltomindbody.com/services/dep...

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Mein Bruder war da und hat das Klavier gestimmt. Und gemeint, man würde so stark merken, was sich bei mir in den letzten 1 - 1 1/2 Jahren getan hat. Selbst darin wie (schnell und auf welche Art) ich auf Nachrichten reagiere, aber vor allem persönlich... #TreatmentResistantDepression #Depression

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Mind blown, Japan is conducting a clinical psilocybin study for treatment resistant depression at Keio University lead by Dr. Hiroyuki Uchida. It gives me hope for Hong Kong

#psilocybin #psychedelicscience #treatmentresistantdepression

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Difficult-to-treat depression affects up to half of people with depression.

It drives disability, costs, and service pressures.

Yet effective add-on treatments are underused.

🧵 THREAD

#DifficultToTreatDepression #TreatmentResistantDepression #MentalHealthPolicy

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Lithium versus Quetiapine in Depression: the results of the LQD study
Lithium versus Quetiapine in Depression: the results of the LQD study Difficult-to-treat depression (sometimes called treatment-resistant depression) affects a large proportion of people living with depression. Many patients don’t respond fully to antidepressants, and…

Calling all mental health prescribers!

20–50% of patients with depression meet criteria for treatment-resistant depression.

Evidence-based options exist, but are underused.

The LQD study tested lithium vs quetiapine as augmentation.

🧵 THREAD #TreatmentResistantDepression

buff.ly/Zvza0o1

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Lithium versus Quetiapine in Depression: the results of the LQD study
Lithium versus Quetiapine in Depression: the results of the LQD study Difficult-to-treat depression (sometimes called treatment-resistant depression) affects a large proportion of people living with depression. Many patients don’t respond fully to antidepressants, and…

If you live with depression, you’ll know treatment doesn’t always work.

About half of people still have symptoms, even after more than one medication.

🧵 THREAD

#DifficultToTreatDepression #TreatmentResistantDepression

buff.ly/BtJ3ydR

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About half of people with depression still have symptoms even after trying more than one medication.

This is called difficult-to-treat depression.

It affects daily life, relationships, and long-term recovery.

🧵 THREAD #DifficultToTreatDepression #TreatmentResistantDepression

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In related news, I wrote this (see screenshot) on 𝕏 this past January (01.02.2025), before I initiated the process of transferring all of my stuff from there over to thee ✨️Promised Land✨️ (this here app of the clear Blue Sky...🦋):

#TRD #treatmentresistantdepression #longtermdepression #depression

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The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in treatment-resistant depression.

A new study of nearly 300,000 people suggests some genetic traits may make depression harder to treat.

🧵 THREAD

#TreatmentResistantDepression #Genetics #BiologicalPsychiatry

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2025 FBI Research Scholars -- James Murrough and Yael Jacob
2025 FBI Research Scholars -- James Murrough and Yael Jacob YouTube video by Icahn School of Medicine

✨Congratulations to Stuti Bansal, Yael Jacob, Laurel Morris & James Murrough for receiving the 2025 Richard and Susan Friedman Research Scholar Award for their project on #TreatmentResistantDepression (TRD). Here, Drs. James Murrough & Yael Jacob discuss their work 👉 www.youtube.com/watch?v=hE7I...

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💡 New hope for difficult-to-treat depression

Many people don’t respond to first-line treatment. What else works?

This webinar shares the latest evidence on meds, psychotherapies, neuromodulation, psychedelics, diet and exercise.

🧵 THREAD

#DifficultToTreatDepression #TreatmentResistantDepression

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Research Finds An Effective Free Tool For Hard-To-Treat Depression And it's cost-effective, too.

"... And as the study authors note, those improvements were comparable to treatment with with antidepressants—at a fraction of the cost."

#mindfulness #depression #depressiontreatment #depressionrelief #treatmentresistantdepression

www.mindbodygreen.com/articles/thi...

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My article describing alternative treatments for treatment resistant depression is on the @NAMIGlendale website. namiglendale.org/alternative-...
#depression #mentalhealth #mentalillness #TMS #esketamine #ECT #psychiatrist #psychologist #treatmentresistantdepression

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