How LSD and classic psychedelics are re-entering modern psychiatry Definium's CMO talks about evaluating psychedelic medicine(s) in the modern era and developing novel treatments for mental health disorders.

The psychedelic renaissance is here. 🧠 Our latest feature explores how LSD is being rigorously researched for anxiety & depression. We spoke with Definium's Dr. Dan Karlin about the science, the stigma, and the future of mental health care. #MentalHealth #LSD #PsychedelicScience #DrugDevelopment

How LSD and classic psychedelics are re-entering modern psychiatry Definium's CMO talks about evaluating psychedelic medicine(s) in the modern era and developing novel treatments for mental health disorders.

The psychedelic renaissance is here. 🧠 Our latest feature explores how LSD is being rigorously researched for anxiety & depression. We spoke with Definium's Dr. Dan Karlin about the science, the stigma, and the future of mental health care. #MentalHealth #LSD #PsychedelicScience #DrugDevelopment

Bottom line: This is a promising signal but we need to be cautious about over interpretation of what are still pilot studies. Good pilot data but not proof psilocybin is superior to existing best treatments.

Big thanks to this team for continuing to provide important data.
#psychedelicscience

New African species confirms evolutionary origin of magic mushrooms A long-standing debate about the evolutionary origin of the world's most widely cultivated "magic mushroom"—Psilocybe cubensis—may now have been settled by scientists from southern Africa and the Unit...

They told Van Der Merwe the older mushrooms were better. So Van Der Merwe went looking….

phys.org/news/2026-03...

#OnlySouthAfricansWillGetThis #PsychedelicScience #DadJoke
🧪🍄

Psychedelic clinical trials measure important outcomes.

But the people who go through these experiences often see dimensions of healing and challenge that standard frameworks miss.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience

Scientists Are Trying to Talk to DMT Entities. The Price Tag Is $9,500. A new $9,500-a-session psychedelic facility on Bequia island aims to establish two-way contact with entities DMT users report encountering. Science or spectacle?

Scientists Are Trying to Talk to DMT Entities. The Price Tag Is $9,500.

#DMT #PsychedelicScience #Consciousness #Psychedelics #AusNews #MentalHealth

thedailyperspective.org/article/2026-03-04-scien...

Post-Psychedelic Integration Self-Assessment Assess your readiness for post-psychedelic integration and gain confidence in your practice. Download our free digital assessment now!

Integration bodywork is not a "whatever practitioner" situation. Dual training matters, even if the bodyworker is coming in before and after the administration session.

#psychedelicscience

Destigmatization, Legalization, and Why Clear Rules Protect Patients

Meet Janina Kowalski, MD, a psychiatrist who underwent ketamine, MDMA, LSD, and psilocybin in experiential therapist training.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #PsychedelicScience

Beyond Lip Service: Meaningful Inclusion of Lived Experience

Meet Simon Amar, MD, a psychiatrist and investigator for MDMA for PTSD and psilocybin for anxiety clinical trials

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience #Psychedelics

MDMA-Assisted Therapy Trial: Safety, Trust, and Returning to Work

Meet Sehrish Sayani, who participated in a Phase 3 MDMA-assisted therapy clinical trial for PTSD.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience #Psychedelics

William James helped lay the foundations of modern psychology.

And yet his insight still challenges us:

What we choose to attend to shapes what we call knowledge.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience #Psychedelics

The Importance of Sharing Nuanced and Difficult Psychedelic Experiences

Meet Will Barone, Psy.D, a clinical psychologist and qualitative researcher in studies with MDMA, psilocybin, & ketamine

#PsychedelicTherapy #PsychedelicResearch #LivedExperience #PsychedelicScience

Join us April 3–5, 2026 for Spirituality & Beyond 6

www.eventbrite.com/e/spirituali...

This moment is from Spirituality & Beyond 5, featuring @RCarhartHarris reflecting on the his entropic brain hypothesis. #psychedelic #psychedelicscience #science #consciousness #psilocybin

Redirecting

There were a lot of weaknesses in this small study, so we shouldn't get too excited from this one trial, but it adds to the body of research on psychedelics' impacts on positive motivational circuits. #psychedelicscience

Read more here: doi.org/10.1016/j.ja...

Inside Group Ketamine-Assisted Therapy: A Firsthand Experience

Meet Jana Sladkova, PhD, who participated in a group ketamine-assisted therapy program for depression.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience #Psychedelics

Our case report was rejected. Looking at feedback, I know what I need now. Which is fine. I'm fine.

Any suggestions on where to submit? We need reviewers who know neuroplastigens and fascia as a vehicle for emotional memory in patterning and molecular terms?

#psychedelicscience #myofascial

Read the paper here: doi.org/10.1556/2054... #psychedelicscience

🧵 First clinical trial ever conducted in a state-regulated psychedelic program just published. Oregon's psilocybin program has served 20,000+ people but the majority are wealthy out-of-state travelers. This study targeted low-income participants to test feasibility. #psychedelicscience

When the six-month follow-up interview comes around and they ask about symptom changes...

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience

Psychedelics are FDA "breakthrough therapies" - but breakthrough for whom? New analysis reveals 85% of US psychedelic trial participants are non-Hispanic White, raising urgent questions about who actually benefits from this "revolution" in mental health. 🧵 #psychedelicscience

Fear Processing in MDMA-Assisted Therapy: A Patient Perspective

Meet Frank Sers from Switzerland who received MDMA and LSD-assisted therapies for depression via compassionate use.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience

The science of psychedelic medicine - Nature Medicine This Review outlines the science behind psychedelic medicine and integrates mechanistic knowledge with clinical evidence across neuropsychiatric indications, highlighting challenges, controversies and...

My take: This is the strongest review of neuroscience findings to date. Lots more in the article.

Read it if you want to stay up to date: doi.org/10.1038/s415...

#psychedelicscience

Meaning Making Intervention in Psychedelic Prep Sessions

Meet Julia King Olivier, MD — psychiatrist, psychedelic therapist, and founder of the Compassionate Care Center in Geneva, Switzerland.

#PsychedelicTherapy #PsychedelicResearch #PatientCenteredCare #LivedExperience #PsychedelicScience

Curious about psychedelics research? Many people explore how low doses of psilocybin are being studied for mood, focus, and creativity.

#MentalHealth #WellnessResearch #PsychedelicScience #Neuroscience #Mushrooms #Psychedelics

The | PICTS | Default Mode Network

- Excerpt from “The Song That Calls You Home”, published under Fair Dealing/Use for reporting, review and critique.

#DefaultModeNetwork
#MentalHealth
#McKenna
#science
#psychedelicscience
#healing
#spiritualgrowth
#Glasgow
#Scotland
#PICTScotland

#psychedelicscience original paper here: doi.org/10.1016/j.ec...

Psychedelic Culture 2026 The Psychedelic Culture Conference brings together leading voices from around the world to explore the intersections of psychedelics with culture, community, and social change.

Honored to be presenting at the Psychedelic Culture 2026 conference in April.

Details in the coming months, as the conference schedule takes shape!

#psychedelics #psychedelicculture #psychedelicscience #consciousness #somatics #cognition #psychology #spirituality

chacruna.net/psychedelic-...

When you see "significant cognitive improvement" in a small, uncontrolled psilocybin study - ask:

Did it exceed practice effects?
Did it persist after controlling for mental health changes/mood improvement?

Here, the answers were mostly no.
#psychedelicscience

New psilocybin cognition study shows "significant improvements" in processing speed & executive function after treatment.

But dig into the data and the picture gets complicated.

A thread on why statistical significance does not equal clinical meaningfulness 🧵

#psychedelicscience

The | PICTS | Recipes

- Excerpt from “Dirty Pictures”, published under Fair Dealing/Use for reporting, review and critique.

#medication
#antidepressants
#placebo
#sideeffects
#spirituality
#psychedelicscience
#psychedelicresearch
#Glasgow
#Scotland
#PICTScotland