The Stoned Ape Hypothesis. Did psilocybin mushrooms help the human brain evolve? According to Terence McKenna, probably!

#TerenceMckenna #StonedApeTheory #HumanEvolution #Psilocybin #Psychedelics

youtu.be/v-5GyV3Spbc?...

Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants Tryptamine psychedelics from plants, fungi, and toads are produced in planta through cross-kingdom pathway reconstruction.

www.science.org/doi/10.1126/...
#agroinfiltration
#pharmaceutical-farming
#psychedelics
Psilocin & psilocybin (mushrooms), DMT (various plants), bufotenin & 5-methoxy-DMT (toads) manufactured in easy-to-cultivate plants (such as tobacco) by alteration of a handful of genes.

One of Priest’s fellow-Episcopalians, a man, reported, “I had a total deconstruction of patriarchal religion.” #fungi #religion #spirituality #psychedelics michaelpollan.com/articles-arc...

Engineered tobacco plant can produce five psychedelics, including psilocybin and DMT Compounds in psychedelic drugs like DMT, psilocybin, and psilocin are naturally produced in certain plants, fungi, and animals, and have a long history of use in spiritual and therapeutic contexts. Now, a considerable amount of research is going into determining how these compounds can be translated into a therapeutic context for several mental health conditions. But to do this, researchers need to find a more sustainable way to source these compounds, as current methods raise ecological and ethical concerns.

Researchers engineered tobacco plants to produce five psychedelic compounds including psilocybin and DMT, opening a more sustainable path for therapeutic production. phys.org/news/2026-04-tobacco-psy... #entheogens #psychedelics

Does New Research Support Terence McKenna's Spores-in-Space Theory? Does new research support Terence Mckenna's Spores-in-Space theory? It seems once again, Mckenna's wisdom was light years ahead of his time.

Does New Research Support Terence McKenna’s Spores-in-Space Theory?

www.wholecelium.com/blog/does-ne...

#terencemckenna #sporesinspacetheory #psychedelics #mushroom

Tobacco plants now produce psilocybin and DMT — on purpose from boingboing rss feed

Tobacco plants now produce psilocybin and DMT — on purpose
boingboing.net/2026/04/02/tobacco-plant...
#dmt #genetic_engineering #pharmaceutical_research #psilocybin #psychedelics #Science #tobacco #Weizmann_Institute #boingboing

What Makes a Competent Psychedelic Therapist Beyond Degrees

Meet Matthew Johnson, PhD, psychedelic researcher, experimental psychologist, senior investigator, and professor at Johns Hopkins University.

#Psychedelics #PsychedelicResearch #PatientCenteredCare

Part 41 of my series “Zen and the Art of Dissatisfaction” is now on my blog at the @helsinkizen.fi website. Read ”Psychedelics and Healing” at helsinkizen.fi/zen-and-the-...
#psychedelics #zenpeacemakers

Engineered tobacco plant produces 5 #Psychedelics simultaneously.

Anne and Alex Shulgin. Ann was a writer, artist, and Jungian lay therapist who was among the first to use MDMA and 2C-B with clients in psychedelic-assisted therapy. Alex was a chemist, pharmacologist, psychopharmacologist, and author. OC. #psychedelic #psychedelics #psychotherapy #therapy

Scientists Create Plant That Produces Ayahuasca, Shrooms, and Toad Psychedelics All At Once The proof-of-concept system produces psilocybin, DMT, and other compounds in leaves of the tobacco plant, potentially easing pressure on wild species and preserving Indigenous traditions.

Tobacco engineered to produce tryptamines... psychedelics.

"Scientists Create Plant That Produces #Ayahuasca, #Shrooms, and Toad #Psychedelics All At Once"

www.404media.co/scientists-c...

Press Release – Announcing Chacruna’s Psychedelic Culture Conference, April 17–19 2026 From April 17–19, 2026, the Chacruna Institute for Psychedelic Plant Medicines will host its signature conference, Psychedelic Culture, at the historic Brava Theater in San Francisco, CA. Bringing tog...

Only two weeks left until I head to Psychedelic Culture 2026.

See some of you there?

chacruna.net/press-releas...

#psychedelics #science #bayarea

Lived experience is not only about sharing stories.

It can reveal blind spots, improve quality and safety, and lead to better decisions in research and care.

The question is whether the field is willing to treat it as expertise, not just perspective.

#Psychedelics #LivedExperience #ClinicalTrials

The WILD history of LSD: Nazi truth serum, the MKUltra plot and feeding acid to your mom...

Norman Ohler, author of Blitzed and Tripped, comes back to the Smart Cookies pod for another fantastic convo 👇🏻

youtu.be/dbRhWEJuQt8

#weirdhistory #darkhistory #psychedelics

Book on shelf: Heads: A Biography of Psychedelic America

holy wow, just realized my book "heads: a biography of psychedelic america" came out 10 years ago this week. available from da capo press through fine independent purveyors of paper, electronic, & audio books! what a baffling time-dilated trip it's been? […]

[Original post on heads.social]

Are you sure you're not feeling it yet?

#psychedelics #trippy #psychonaut

Lived experience may be welcomed into the conversation, but rarely trusted with real authority.

That gap matters.

Because inclusion is not the same as influence, and consultation is not the same as shared decision-making.

#Psychedelics #LivedExperienceExpertise #ClinicalTrials

The Molecules That Might Save Us 84.5 million Americans had a mental illness or substance use disorder in 2023, and the treatments we have are failing most of them. Psychedelic-assisted therapy produces clinical results that conventi...

The Molecules That Might Save Us spicanews.com/articles/psy...

#mushrooms
#psychedelics

AOC Slams Federal Drug Laws That Restrict Marijuana And Psychedelics Despite Their Medical Value - Marijuana Moment Rep. Alexandria Ocasio-Cortez (D-NY) tore into the current U.S. drug scheduling system on Thursday—making the case that placing substances like marijuana and LSD in the most restrictive category runs ...

"Rep. Alexandria Ocasio-Cortez (D-NY) tore into the current U.S. drug scheduling system on Thursday—making the case that placing substances like marijuana and LSD in the most restrictive category runs counter to evidence showing their medical potential"
#Medical #Marijuana #Cannabis #Psychedelics

Flier for an author event featuring Karuna Das at Stay Gold Books on Thursday, April 2 at 7 PM.

Re-release celebration for my award-winning novels! Thursday, April 2, 7 PM, Regent Square neighborhood of Pittsburgh!

#authorlife #writingcommunity #bookrelease #scifi #scifibooks #visionaryfiction #lgbtqfiction #newadultfiction #consciousness #evolutionarybiology #psychedelics #spiritualawakening

Psychedelics and the Fear of Losing Control - Dualistic Unity Psychedelics don’t expand reality — they widen the narrow window we perceive it through. This explores ego, control, and why openness can feel frightening.

Anxiety during a psychedelic experience often peaks when someone tries to resist what’s unfolding. What changes when resistance itself becomes visible?

dualisticunity.com/psychedelics...

#Psychedelics #InnerWork

Today's StockBox #podcast we discuss:

✅ @cadenceminerals.bsky.social #KDNC
✅ Critical Mineral Resources #CMR
✅ Beeks Group #BKS
✅ Red Light #TRIP

#lithium #ironore ##copper #silver #PoweredByBeeks #blockchain #psychedelics #mushroomkits #redlightholland #Investing

youtu.be/OYvO1i5-L8Q

Extended State Dimethyltryptamine (DMT): Psychedelic Renaissance Progresses to Psychedelic Enlightenment Extended state DMT research extends the typically brief psychedelic experience, enabling sustained, controlled exploration of consciousness. Rooted in longstanding South American shamanic traditions, ...

New @chacruna.bsky.social Chronicles article from Chacruna course graduate Heather Hannah - "Extended States: A Renaissance Progressing Toward Enlightenment”

chacruna.net/extended-sta...

#psychedelics #dmt #medsky

Novel Psychedelic Promising on Resistant Depression An investigative inhaled formulation of the psychedelic mebufotenin is linked to significant improvements in depression symptoms compared to placebo, a phase 2b trial shows.

The drug, GH001, is a synthetic inhaled formulation of mebufotenin(5-MeO-DMT), under development by GH Research. Mebufotenin is found in nature in seeds, bark, and leaves of a number of plants in the Amazonian rainforest and in the venom of some toad species.

#trauma #mentalhealth #psychedelics

First direct comparison of MDMA and MDA reveals distinct psychedelic differences A new clinical trial directly compares MDMA with its chemical relative MDA for the first time. The results reveal how slight molecular differences can dramatically alter the duration, visual intensity, and adverse effects of psychoactive drugs.

First direct comparison of MDMA and MDA reveals distinct psychedelic differences #Science #HealthandMedicine #MentalHealth #MDMA #Psychedelics

www.psypost.org/first-direct-comparison-...

Scientists are pairing psychedelics with virtual reality to support brain healing. #Psychedelics increase neuroplasticity, while #VR guides rewiring through controlled sensory input.

This may help retrain disrupted networks in real time. Learn more via the link in bio.

In 2023, the FDA issued draft guidance on clinical investigations for psychedelic drugs. The document says it is meant to give sponsors general considerations for developing psychedelic drugs for medical conditions, including trial conduct, data collection, and subject safety.

#Psychedelics #FDA

Could Psychedelic Ketamine Therapy Cure Alcohol Addiction? The drug might be able to "rewire the disappointment center" in your brain

Could Psychedelic Ketamine Therapy Cure Alcohol Addiction?

www.insidehook.com/wellness/ket...

#News #WorldNews #Science #Research #Health #Wellness #Medicine #Medical #Medsky #Ketamine #Psychedelics #Alcohol #Addiction #Alcoholism #Relapse #MentalHealth #Sober

A new study measures the temporal distortions caused by psychedelics A placebo-controlled experiment reveals how psilocybin changes human time perception. By testing volunteers on a visual timing task, researchers found the psychedelic compound causes people to underestimate durations and feel time passing much slower than normal.

A new study measures the temporal distortions caused by psychedelics #Science #Psychology #Other #Psychedelics #Neuroscience #TemporalDistortion

www.psypost.org/psilocybin-alters-time-p...