Left: Experimental design featuring eight conditions with two distinct tones (A and B) and a 5% omission rate, presented in random order. Each condition comprised 1,000 stimulus items, varying the probability of Tones A and B to achieve different predictability levels. Top right: Example of a neuron that responds to tones but not to omissions. The raster plot shows spikes (black dots) with time (ms) on the x-axis and trials on the y-axis. The PSTH displays firing rate over time, with tone stimuli (blue shading) and omissions (gray shading). The black line represents the firing rate, the red line shows omission responses, and the green line indicates the omission baseline. Bottom right: Example of a neuron that selectively responds to the omission of specific tones. The same representation is used as in top right.
The sound of silence? @yaronamit.bsky.social &co show how #neurons encoding negative #PredictionErrors in the #AuditorySystem compute the omission of sounds in a predictable tone sequence (incl asymmetry between bottom-up receptive field & top-down predictive field @plosbiology.org 🧪 plos.io/4n61zeq
