Integrative GWAS and Mendelian Randomization Analysis Identifies IREB2 and CD27+ Memory B Cells as Core Drivers of COPD to Lung Cancer Progression This flowchart outlines our integrative pipeline. We linked COPD phenotypes and lung function with lung cancer in NHANES, then applied GWAS, Mendelian Randomization (MR), and colocalization to identi...

#Article in #MedComm
Integrative GWAS and Mendelian Randomization Analysis Identifies IREB2 and CD27+ Memory B Cells as Core Drivers of #COPD to Lung #Cancer Progression doi.org/10.1002/mco2...

#GWAS #IREB22 #LungCancer #MendelianRandomization #B_cell

Prof Tullia Bruno #B_Cell GURU @ #UPMC reviews #TLS & then dives into “DO NOT POST” differences in TLS btwn #melanoma & #LungCancer brain #metastases /soon 2 b submitted/ #Bridge2024 @sitcancer.bsky.social @robertferrismdphd.bsky.social #FinishCancer