Admire the iridescent sheen of Pseudomonas aeruginosa!
#BacterioMed
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🔬🎨 Microbiologie ou art abstrait ?
Le 10 mars à 16h, je parlerai du #microbiote vaginal à l’Université de Bretagne Occidentale, dans le cadre du Festival RESSAC.
La conférence sera croquée en direct en BD par Margaux Lhuissier.
📍 10 mars, 16h
📍 UFR Médecine, amphi IV
🎟️ Entrée libre #BacterioMed
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#BacterioMed 🧫 “Pseudomonas-petroleum”
Decoding the image: the characteristic metallic sheen of the pyocyanic bacillus, Pseudomonas aeruginosa.
This strain is mucoid, a hallmark of chronic colonization in the respiratory tract of a patient with bronchiectasis.
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[Case Report] 🧬🩸Culture-negative endocarditis diagnosed in our lab using microbial cfDNA blood metagenomics (Disqver® test, Noscendo). A non-invasive approach that proved decisive in a pregnant patient.
#mNGS #metagenomics #InfectiveEndocarditis #BacterioMed @asm.org journals.asm.org/eprint/2JMM5...
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#BacterioMed Still mixing up resistance vs phenotypic tolerance vs persistence? This figure from Helaine lab’s review lays the three survival modes out beautifully.
doi:10.1016/j.chom.2024.04.019
@cellpress.bsky.social @cp-cellhostmicrobe.bsky.social
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#BacterioMed Colors of the day.
Pseudomonas aeruginosa, an absolutely fascinating species.
I never get tired of its palette 🎨.
A reminder that even the most formidable pathogens can be strikingly beautiful. Science never stops amazing. 🧫
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#BacterioMed This Serratia marcescens strain was isolated from the sputum of a patient with chronic lung disease. 🫁
The emergence of a mucoid phenotype is never trivial in clinical microbiology, and synonymous of chronic infection, biofilm, persistence, particularly within the respiratory tract. 🧫
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Huge thanks to our lab’s Santa 🎅🎁 This mug is pure magic! 🌈
#BacterioMed
Merry Christmas to all microbiologists! 🎄🧫✨
@sfmicrobiologie.bsky.social @jm-sfm.bsky.social
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🧫 #BacterioMed Staphylococcus aureus in all its forms.
The most observant 👀 will spot 3 distinct morphotypes, including a small-colony variant.
Sputum from a #cysticfibrosis patient still requiring antibiotics despite triple therapy. A reminder that the infectious challenge remains very real in CF.
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#BacterioMed Recurrent Clostridioides difficile infections
affect 14%-16% of patients with CDI. Up to 50% of rCDI is caused by ingestion of spores from a new toxin-producing strain. FMT: after 2 or more CDI recurrences and first-line antibiotic treatment.
jamanetwork.com/journals/jam...
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#BacterioMed This new WHO report presents a global analysis of antibiotic resistance prevalence/trends, drawing on ~23 million bacteriologically confirmed cases of bloodstream infections, urinary tract infections, gastrointestinal infections, and urogenital gonorrhoea. www.who.int/publications...
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🧫 The scars of war also appear in the antibiogram. #BacterioMed
A Ukrainian war-injured patient, with a Citrobacter freundii osteitis producing a carbapenemase. The first-line antibiogram offered almost no therapeutic options.
#AntimicrobialResistance #WarAndHealth #GlobalHealth
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✨ Just for the sheer beauty of bacteria: the metallic, iridescent sheen of #Pseudomonas aeruginosa.
🧫 A pathogen… but also an artist of light and color when grown in culture. #BacterioMed #ScienceArt @sfmicrobiologie.bsky.social @jm-sfm.bsky.social @ricaifrance.bsky.social
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#BacterioMed Uncommon antibiotype for Citrobacter farmeri, showing a hyper OXY-like profile.
C. farmeri belongs to the Citrobacter amalonaticus group.
⚠️ Beware: immunochromatographic tests may misidentify it as CTX-M. This resistance in C. farmeri is chromosomally encoded.
doi.org/10.1016/j.di...
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#GramArt Nothing bacterial here. Just the quiet beauty of a blood smear, where staining artifacts sketch out something close to art. #BacterioMed
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#BacterioMed Bacteremia caused by Lactobacillus plantarum (Lactiplantibacillus plantarum) in a patient who underwent digestive surgery.
So glad to have had early identification right from the Gram stain: crucial for guiding probabilistic antibiotic therapy, given this species’ resistance profile.
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#BacterioMed The mucoidy of P. aeruginosa can be seen right from the Gram for expert eyes. Note the thick gangue surrounding Gram-negative bacilli: it corresponds to the exopolysaccharides produced by the bacteria. It's easy to see why antibiotics are not very effective at this stage of 🫁infection.
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#BacterioMed The consequences of the war in 🇺🇦 can also be seen in health terms, with the accelerated spread of antibiotic resistance. Strain of K. pneumoniae producing carbapenemase (KPC) isolated from a severely wounded and infected Ukrainian soldier (bone infection from war wounds). #CPE
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#BacterioMed It's spring in the Petri dishes too! 🧫🌼
A magnificent group B streptococcus producing its carotenoid pigment 🥕(grenadaene) aerobically and on chocolate agar.
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#BacterioMed Lovely metallic iridescent sheen of #Pseudomonas aeruginosa. First described in 1964! Back then, it didn’t take much to get published in Nature ;)
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#BacterioMed #CysticFibrosis Investigation of #Mycobacterium_abscessus transmission. WGS revealed dominant circulating clones in 🫁 and🚰 isolates. Epidemiological links supported the role of drinking water as a reservoir for Mabs.
www-atsjournals-org.proxy.insermbiblio.inist.fr/doi/10.1164/...
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#BacterioMed Looks like the normobiosis is finally going to be characterised.
Data from 45,424 human gut #microbiome allowed to define a health-associated core keystone (HACK) index. www.cell.com/cell-reports...
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#BacterioMed The most beautiful #Pseudomonas aeruginosa … of the day.
Small patches = metabolic autolysis or prophage lysis?
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#BacterioMed This is a case of #Pseudomonas aeruginosa bacteremia.
Observe the rectilinear motility of this mono-flagellated bacterium in a fresh state (x40 magnification under the 🔬). The bacilli moving fast and straight between the red blood cells can be clearly distinguished.
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🌸 Happy New Year to all my dear microbiology fellows 🌸 !
@sfmicrobiologie.bsky.social @jm-sfm.bsky.social
#AgarArt 🧫 #BacterioMed
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