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Two bar plots from the paper:

Yearly numbers of publications in PubMed from 1965 to 2025 on mathematical modelling in endocrinology and diabetes with (left) and without (right) machine learning.

Search terms were “(“mathematical modelling” OR “computer simulation” OR “machine learning”) AND (endocrinology OR endocrine OR hormone OR hormonal OR diabetes)” for the left plot and “(“mathematical modelling” OR “computer simulation”) AND (endocrinology OR endocrine OR hormone OR hormonal OR diabetes)” for the right plot.

The left chart shows a dramatic increase, peaking sharply in the year 2025 at nearly 3000 publications. The right chart shows moderate growth with peaks around four hundred around the year 2025.

Two bar plots from the paper: Yearly numbers of publications in PubMed from 1965 to 2025 on mathematical modelling in endocrinology and diabetes with (left) and without (right) machine learning. Search terms were “(“mathematical modelling” OR “computer simulation” OR “machine learning”) AND (endocrinology OR endocrine OR hormone OR hormonal OR diabetes)” for the left plot and “(“mathematical modelling” OR “computer simulation”) AND (endocrinology OR endocrine OR hormone OR hormonal OR diabetes)” for the right plot. The left chart shows a dramatic increase, peaking sharply in the year 2025 at nearly 3000 publications. The right chart shows moderate growth with peaks around four hundred around the year 2025.

Mathematical modelling, computer #simulation, and machine learning upgrade #endocrinology. Applying principles of #biocybernetics and #biophysics, they enjoy growing interest and deliver novel methods for research, diagnosis, and therapy.

pubmed.ncbi.nlm.nih.gov/41852474/
doi.org/10.3389/fend...

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Figure from the book "Hypothyroidism: A Paradigm Shift" by Hoermann and Dietrich: Combination of peripheral and central mechanisms leading to the low-T3 syndrome. The activities of peripheral (GD1) and central (GD2) deiodinases diverge to cause the low-T3 phenotype. The graph shown has been produced by computer simulation with the free app SimThyr.

Figure from the book "Hypothyroidism: A Paradigm Shift" by Hoermann and Dietrich: Combination of peripheral and central mechanisms leading to the low-T3 syndrome. The activities of peripheral (GD1) and central (GD2) deiodinases diverge to cause the low-T3 phenotype. The graph shown has been produced by computer simulation with the free app SimThyr.

Computer simulations with #SimThyr enhance our understanding of the physiology of hypothalamic-pituitary-thyroid feedback control. This applies, for example, to the evolution of #TACITUS syndrome.

#thyroid #hypothyroidism #NTIS #biocybernetics

doi.org/10.1007/978-...

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A Primer on Cyber-Physical Systems in the Fourth Industrial Revolution

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Echos in the Past: The Crystal Palace, the World's Fairs, and the New Electricity

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#BioCybernetics #Cascadia #Climate #CrystalCity #CyberPhysical #Ecology #Eurasia #Indigenism #Intelligence #RussoAmerican #Sustainability #Symbiosis #Time #WorldsFair #AI

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#Symbiosis #Sentience #AGI #Ecosystems #Blockchain #AI #Ecology #Substrate #SelfOrganization #Energy #Emergence #Crypto #BioCybernetics #Consciousness #DARPA

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