Epigenetics Update - Bivalent chromatin instructs lineage specification during hematopoiesis bit.ly/3G4GmRv

Hanno Hock and Konrad Hochedlinger (Harvard) reporting in Cell

#Epigenetics #BivalentDomains #Hematopoiesis

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Gain deeper insights into gene regulation at epigenometech.com

Text reads: News - Repressed but ready to go: how intricate molecular interactions establish responsiveness to gene expression cues that shape development. Image shows two immunofluorescence images of embryonic stem cells cultured to differentiate into neurons. The bottom image show the effect of a gene deletion on the ability of the cells to differentiate into neurons, demonstrated by the loss of a neuron-specific protein identified by green immunofluorescence. Blue shows DNA.

RESEARCH NEWS: #epigenetics research from the Voigt lab uncovering "a key mechanism that has so far eluded experimental scrutiny."

Thursday reading for anyone interested in #BivalentDomains #Histones #GeneRegulation in development #ESCs 🧪

www.babraham.ac.uk/news/2025/02...

Epigenetics Update - Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A–menin to bivalent promoters bit.ly/4gbO0Wt

Ping Chi and Yu Chen reporting in Nature Genetics

#Epigenetics #BivalentDomains
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Discover the breakthrough at epigenome.us

Epigenetics Update - Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains bit.ly/4098aLL

Philipp Voigt from the Uni. of Edinburgh/Babraham Institute in Molecular Cell

#Epigenetics #ESCs #BivalentDomains
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Gain deep insight into gene regulation: epigenome.us